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Australia starts peanut allergy treatment for babies

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Re: Australia starts peanut allergy treatment for babies

#81
post #34

When I worked at a wilderness summer camp I had a kid in my group that was deathly allergic to peanuts, so weeks before we had to rid the camp of them. He was about 13, and said when he was little they did that scratch allergy test on his arm and he was in a coma for six months. He carried and Epipen around but told me not to stress. If someone ate a snickers then touched a door knob, and he touched it days later he…

Slight tangent: How do people with an allergy that severe find out they have an allergy? For example people who know even someone's breath after eating peanuts would threaten their lives. Accidental exposures are likely much worse than that, so how do you end up learning about this severity without dying in the first place? Just running a full allergy test after an unexplained exposure to traces of "something", or...…

For my son, it was another child kissing him on the head when my child was about 6 months old, the child had eaten peanut butter for breakfast. His face started to swell, and my wife ran him to a local GP - and with wiping down and plenty of breast milk he was OK. A month or two later he was at a toddler party and rolled in a little hummus - and the same thing happened. We were already on the list for an allergy appointment, but they wouldn't see him until he was 18 months old - so we found a private hospital who would see him.

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In terms of 'cause' - we don't know, one or two other children of my sons generation in our family have food allergies, and an older brother thought he was allergic to fish though never tested.

We noticed the reaction after he had a round of antibiotics after he had infected eczema, quickly followed by my wife needing antibiotics which we are sure got to him through her milk, as he'd groan after breast feeding - before that we had plenty of nuts, sesame, milk and eggs in the house, without noticing an issue for him. But that is just a pet theory.

Re: Australia starts peanut allergy treatment for babies

#82

Earlier quoted context omitted.

So, at the end of a long thread full of information that discards genetics, your explanation for it is... genetics.

I took it as a warning about potential misinterpretation of causes and effects, and in particular the difficulty to assign a single cause to the near absence of allergy in a population. Allergies are a subject I need to know a lot more about, so sadly at this point I don't have an explanation for anything.

Yet you are the one insisting on a single cause.

Re: Australia starts peanut allergy treatment for babies

#83

Earlier quoted context omitted.

I took it as a warning about potential misinterpretation of causes and effects, and in particular the difficulty to assign a single cause to the near absence of allergy in a population. Allergies are a subject I need to know a lot more about, so sadly at this point I don't have an explanation for anything.

Yet you are the one insisting on a single cause.

Having some babies get hit at early age by allergies doesn't exclude any other mechanism running in parallel, including other babies adapting their immune system, or even families moving out of the country for health reason.

I don't see how any of what I said is either insistant or limiting to a single cause.

Re: Australia starts peanut allergy treatment for babies

#84

Immunotherapy works. I run a company (YC w21) that wants to eliminate allergies forever. It's ancient medicine to manage symptoms with antihistamines when we can remove the root cause completely. Right now, we fix cat, dog, pet, pollen, and dust allergies. In a few years, we'll be doing nuts. Our launch HN: https://news.ycombinator.com/item?id=26227807 company: https://www.wyndly.com/ book a visit with a doc: https:/…

Can you show us any peer reviewed paper ?

Re: Australia starts peanut allergy treatment for babies

#85

In The Netherlands it is recommended to introduce peanut and egg to babies between 4 and 6 months, to reduce the chances of food allergy. More information (in Dutch): https://www.voedingscentrum.nl/nl/service/vraag-en-antwoord/...

Where does the peanut and egg allergy come from? My understanding is that peanut oil and egg albumin are ingredients in many common medicines given early to infants.. is there any chance that could be contributing?

Re: Australia starts peanut allergy treatment for babies

#86

In The Netherlands it is recommended to introduce peanut and egg to babies between 4 and 6 months, to reduce the chances of food allergy. More information (in Dutch): https://www.voedingscentrum.nl/nl/service/vraag-en-antwoord/...

That's the current guidance in the US as well. https://mana.md/peanut-allergies-may-affect-your-child/

How have outcomes improved since the guidance?

Re: Australia starts peanut allergy treatment for babies

#88

I always think about the low incidence of peanut allergies in developing countries and wonder if the mother's diet during pregnancy has an effect on allergies in children? Has this been researched? Because instead of introducing peanuts and eggs to babies, introducing it to mothers is almost a no brainer.

It most likely has to do with how bored our immune systems are. We evolved to be constantly dirty, and we live in an extremely clean society. When your immune system has a lot to fight, it doesn't worry to much about dumb shit like pollen and peanuts.

The immune system doesn't know how to rest. It must always fight something.

So if it runs out of intruders to fight, it will attack the body itself.

Re: Australia starts peanut allergy treatment for babies

#89

Immunotherapy works. I run a company (YC w21) that wants to eliminate allergies forever. It's ancient medicine to manage symptoms with antihistamines when we can remove the root cause completely. Right now, we fix cat, dog, pet, pollen, and dust allergies. In a few years, we'll be doing nuts. Our launch HN: https://news.ycombinator.com/item?id=26227807 company: https://www.wyndly.com/ book a visit with a doc: https:/…

This is a brilliant idea. The product and system also look extremely well put together.

Re: Australia starts peanut allergy treatment for babies

#90
post #33

Earlier quoted context omitted.

Sorry for being nosy, but did you do oral immunotherapy with or without professional support?

I AM NOT A DOCTOR OR OTHER HEALTHCARE PROFESSIONAL I looked into oral immunotherapy for tree nut allergies. There's a paper from 2022: https://onlinelibrary.wiley.com/doi/10.1111/all.15212 They did it in a few stages: 1. First three days: test the child with increasing amounts of cashew protein, until the child has a reaction. Use the amount ingested for that reaction, to determine the single highest tolerated dose (…

For curiosity sake, curious if the tree nut allergy here was typical reactions (hives, nose, etc.)?

I have a tree nut "allergy" but doctors always call it more of a "hypersensitivity" because my reactions are usually involving terrible stomach cramps and pain accompanied occasionally by swollen throat (more so for almonds than cashews).

I've wondered if it's worth trying to do this myself.

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