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HPV vaccine study finds zero cases of cervical cancer among women vaccinated <14

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Re: HPV vaccine study finds zero cases of cervical cancer among women vaccinated <14

#81

Post by pazimzadeh »

londons_explore wrote: post #45
pazimzadeh wrote: post #39

Earlier quoted context omitted.

I don't understand why they recommend against it. I guess the monetary costs don't outweigh the benefits, but that's only if you care more about saving money than potentially preventing cancer. It's not like the vaccine going to hurt you. But the HPV vaccine is not particularly cheap, so it sounds like the insurance companies have lobbied against it or something. In my opinion men should also be vaccinated for it sin…

Since nearly everyone is infected with HPV, if you've had sex with a few people you're almost certainly already infected and therefore the vaccine will be of no benefit. I guess if you were 50 and still a virgin, and planning to change that, it might be worth it.

How can you be sure there would be no benefit? When my mom was diagnosed with stage four HPV-positive cancer, they still gave her the vaccine on the off chance that it would induce an immune response.

Re: HPV vaccine study finds zero cases of cervical cancer among women vaccinated <14

#82

Post by Gibbon1 »

Moldoteck wrote: post #24

Does it make sense to get a vaccine for older ppl, like 30y, does this still apply for men?

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580486/

Seems to say that for a subset of people HPV infection is latent. But current vaccines aren't useful against latent infections. Quick skimming says therapeutic vaccines are an area of research. "Numerous DNA-based vaccines have been developed to target persistent HPV infection and are currently in various stages of clinical study"

My thought is watch this space.

Re: HPV vaccine study finds zero cases of cervical cancer among women vaccinated <14

#83

Post by Benanov »

ksenzee wrote: post #68
Traubenfuchs wrote: post #12

The continuing focus on cervical cancer and women’s sexual health in the context of HPV (vaccination) is my biggest pet peeve ever. HPV causes penile, anal, mouth-throat and cervical cancer. I‘d argue that all of those cancers are much, much worse than cervical cancer. After all, they can cause permanent disfigurement, chronic pain, inability to ever speak again and loss of the penis. Infertility? Woe is me! Anyone w…

Cervical cancer kills. I don’t think you mean “it’s worse for a man to lose his penis than for a woman to die” but that’s how it’s coming across. And that’s unfortunate because your point is entirely valid: men are not nearly terrified enough of HPV.

I saw it as more along the lines of "this is why men should get it" - the context is already established that HPV should scare men and here's why...

Re: HPV vaccine study finds zero cases of cervical cancer among women vaccinated <14

#84

Post by volkl48 »

londons_explore wrote: post #45
pazimzadeh wrote: post #39

Earlier quoted context omitted.

I don't understand why they recommend against it. I guess the monetary costs don't outweigh the benefits, but that's only if you care more about saving money than potentially preventing cancer. It's not like the vaccine going to hurt you. But the HPV vaccine is not particularly cheap, so it sounds like the insurance companies have lobbied against it or something. In my opinion men should also be vaccinated for it sin…

Since nearly everyone is infected with HPV, if you've had sex with a few people you're almost certainly already infected and therefore the vaccine will be of no benefit. I guess if you were 50 and still a virgin, and planning to change that, it might be worth it.

Yes, but being infected with one strain isn't the same as being infected with all of them in terms of the risks. You are unlikely to have all the strains known to cause problems already.

-------

Additionally (something I only became aware of from knowing a person dealing with it) - there's a modest body of clinical research suggesting that vaccinating for HPV in someone who already has it and is symptomatic (warts) can significantly lessen or eliminate their symptoms.

It was recommended for the person I know on that basis by their doctor as a thing to try, and they've noticed significant improvement. Anectdata, but mentioning anyway.

These are very small studies and I won't claim that this is definitive (nor that I've put that much effort into a review of all literature), but to provide some support for my claims that this is a thing being suggested/investigated in research:

- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541142/

- https://pubmed.ncbi.nlm.nih.gov/38068369/

---------

I believe that it's too early in the research for that to be factoring into the analysis going into current CDC recommendations, but it's an additional possible upside of vaccination (reducing symptoms/likelihood of symptoms, even if already infected) if the research continues to pan out.

Re: HPV vaccine study finds zero cases of cervical cancer among women vaccinated <14

#85

Post by kstrauser »

alfor wrote: post #74
tick_tock_tick wrote: post #2

It's so crazy/impressive to me that some vaccines are actually "prefect".

[flagged]

> We assume the cost is zero but it's not.

Please share. What's the health cost of getting this vaccine?

Re: HPV vaccine study finds zero cases of cervical cancer among women vaccinated <14

#86

Post by tasty_freeze »

Traubenfuchs wrote: post #12

The continuing focus on cervical cancer and women’s sexual health in the context of HPV (vaccination) is my biggest pet peeve ever. HPV causes penile, anal, mouth-throat and cervical cancer. I‘d argue that all of those cancers are much, much worse than cervical cancer. After all, they can cause permanent disfigurement, chronic pain, inability to ever speak again and loss of the penis. Infertility? Woe is me! Anyone w…

> Woe is me!

Do you think infertility is the only consequence of cervical cancer? Do you mock children with with leukemia saying, "Oh, you feel a little tired? Get over yourself?"

For many people treatment goes smoothly and the can get on with their lives. For some they get treatment, it comes back, they get more treatment, it comes back, and they die, and there is a range of options in between. Maybe they don't die but they can no longer have intercourse. Maybe the financial strain of many rounds of treatment puts them in life-changing debt.

Don't be so glib with the misfortune of other people.

Re: HPV vaccine study finds zero cases of cervical cancer among women vaccinated <14

#87

Post by kstrauser »

NotGMan wrote: post #22
jeffbee wrote: post #10

This is one of the many reasons that "parental rights" people are dead wrong. People as young as 12 should have the absolute right to seek and get, in confidence, this vaccine and other health care. Nobody should give any weight to whether their parents want them to not have this vaccine.

[flagged]

I always love the presumption that "big pharma" is the same worldwide, and therefore non-US countries' health organizations are in on the "big lie".

Re: HPV vaccine study finds zero cases of cervical cancer among women vaccinated <14

#88

Post by iraqmtpizza »

ceejayoz wrote: post #80
iraqmtpizza wrote: post #77

Earlier quoted context omitted.

[flagged]

Child rape is a situation where it shouldn't matter how many people approve. If your twelve year old wants to have sex, and you with your "parents' rights" endorse that choice, you should go to jail . Because your right as a parent to make decisions is in conflict with the right of the child not to be subject to statutory rape. The poster upthread asserts a similar conflict between the rights of the parent to make de…

Actually you make a good point. Nobody should be penetrating children, regardless of what the parents think — kids can get irreversible medical procedures when they turn 18.

Re: HPV vaccine study finds zero cases of cervical cancer among women vaccinated <14

#89

Post by kstrauser »

alfor wrote: post #76
jmyeet wrote: post #58

Earlier quoted context omitted.

Children have rights. Parents have responsibilities. Vaccines are a medical miracle. Never except that being an anti-vaxxer (or a "vaccine skeptic", which is the sanitized name for the same thing) as being on equal footing. Vaccines are evidence-based. Anti-vaxxers are vibes-based.

[flagged]

You keep bringing this up. Go ahead, share the peer reviewed articles that support your claim. I'd love to see them!

Re: HPV vaccine study finds zero cases of cervical cancer among women vaccinated <14

#90

Post by dyslexit »

lancebeet wrote: post #13

It seems a little strange to me that the people interviewed in this article find this is so remarkable. Only 40,000 people belonged to the group that got the vaccine before 14. If the incidence rate were the same as for the unvaccinated (8.4 per 100k) you would have expected roughly 4 in the group to have gotten cancer. If the incidence rate were the same as for those vaccinated after 14 (3.2 per 100k), you would hav…

The incidence rate is per year and the study was over an average of 32 years per patient. At that rate you'd expect around 105 incidents instead of 4, although there are other considerations like age to take into account.
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