I prefer having time for myself rather than killing myself at work hoping that it will pay out. If it does, great for you! But if it doesn't, all those years you've worked your ass off and didn't have time for yourself and people close to you will never be given back. I have my good salary at BigCo and I know that the moment I leave the office, I don't have to think about it.
I think this work / life separation is really important (to me at least). I don't personally think that what you do at work represents who you really are, and having activities outside of work defines you way more than that thing you do from 9 to 5 to earn a salary. In the end, a job is only there to provide you enough money to pay for your lifestyle.
If your personnal goal is to be crazy rich, then go and work your ass off like crazy for years. But when your job pays enough that you can keep your current lifestyle and you like what you're doing like this, I don't see anything that would make me leave BigCo for a startup filled with dreams of being rich.