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Cannabis use disorder and subsequent risk of depression and bipolar disorder

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Re: Cannabis use disorder and subsequent risk of depression and bipolar disorder

#81

Post by klyrs »

daft_pink wrote: post #6
tptacek wrote: post #2

"Cannabis Use Disorder", not "Cannabis use". The appropriate title is "Cannabis Use Disorder and Subsequent Risk of Psychotic and Nonpsychotic Unipolar Depression and Bipolar Disorder".

Have you ever met someone with schizophrenia? I would never engage in any activity that increases the likelihood of a permanent life ruining mental illness!

> I would never engage in any activity that increases the likelihood of a permanent life ruining mental illness!

You wouldn't even try Being Wrong on the Internet even once? I have. It's highly addictive.

Re: Cannabis use disorder and subsequent risk of depression and bipolar disorder

#82

Post by glouwbug »

shawnz wrote: post #24
daft_pink wrote: post #6

Earlier quoted context omitted.

Have you ever met someone with schizophrenia? I would never engage in any activity that increases the likelihood of a permanent life ruining mental illness!

That statement is obviously not true in an absolute sense, for example, do you avoid driving cars due to the chance of acquiring PTSD after a severe accident?

I mean, I do. But I’m also slightly anxious

Re: Cannabis use disorder and subsequent risk of depression and bipolar disorder

#83

Post by ajfdsaaj4e4ea »

I'm terrified of seeking help for mental illness because certain diagnosis can have legal impacts. It is a sad truth, no one has a real response for it except "get over it", and it is very, very difficult to get support for political reforms to protect the mentally ill.

I am also terrified the medications we force on some mental health patients, especially injected long-term ones, are purely for the benefit of the care taker and not the individual.

I think cannabis had fell into a niche of "self-medication", for people who the system doesn't seem to work for. Cannabis nor alcohol are the ideal medications, they are simply the only ones most easily available.

Re: Cannabis use disorder and subsequent risk of depression and bipolar disorder

#84

Post by avodonosov »

pseudocomposer wrote: post #66
avodonosov wrote: post #55

Earlier quoted context omitted.

Isn't it possible to distinguish casuality between A and B from correlation by simply considering set sizes? !A & B A & !B A & B !A & !B A B !A !B

Could you explain which distributions you think are correlation and which are causation?

I hoped someone who knows statistics will just tell us, instead of me stretching my brain.

The famous phrase "correlation does not mean casuation" is not equal to "correlation is indistingushable from casuation", but that's how people seem to often treat it.

Ideally, the paper abstract should be clear about what can or can not be concluded. In the title they say "subsequent" as if suggesting casuality, but in the abstract they say "associated". Confusing for a layman such as me.

My intuition of how to distinguish correlation from casuation:

If cannabis and depression were symmetrically connected, then incease of chances for cannabis use between depressed was equal to the increase of chances for depression between cannabis users.

If cannabis increases chances for depression more that depression increases chances for cannabis, than we conclude cannabis tends to cause depression.

Formula: percentage of depressed between canabis users / percentage of depressed in general population > persentage of cannabis users between depressed / persentage of cannabis users in general population.

Something like that.

Re: Cannabis use disorder and subsequent risk of depression and bipolar disorder

#85

Post by PheonixPharts »

avodonosov wrote: post #55
sandofsky wrote: post #26

I can't see the full study methodology without an account. That said… The challenge with running studies ethically is that you can't split your test groups into two groups and somehow induce cannabis use disorder and see if major depression, bipolar, etc results from it. Rather, you can see if the people who naturally develop the disorder also have those problems. The flaw in this reasoning is that people who develop…

Isn't it possible to distinguish casuality between A and B from correlation by simply considering set sizes? !A & B A & !B A & B !A & !B A B !A !B

No because you can never know for sure that there isn't a latent factor C which is the real causal factor and A is merely correlating with it (if we presume causality to exist at all, which is a pretty standard assumption).

We can compose DAGs that control for the factors we do know about, but it's impossible to exhaust or even know all possible latent processes that are impacting the outcome.

Re: Cannabis use disorder and subsequent risk of depression and bipolar disorder

#86

Post by fallat »

kromem wrote: post #54
kikokikokiko wrote: post #27

Does it really surprises anyone that a psychoactive drug have psychoactive effects on it's users? This whole "cannabis is an inofensive natural plant" is so dumb, of course a drug that alters your mind and is used regularly will produce side effects on it's users. The other thing that I always try to warn my pot head friends is about the pulmonary risks involved in cannabis use. I know guys that smoke all day pretty…

As it naturally occurs it probably was fairly innocuous in longer term psychoactive effects. Heirloom strains had CBD alongside THC. CBD on its own has been as effective in research as antipsychotics in treating schizophrenia, and very much mitigates the OP effects in research. But the vast majority of product today has selectively bred out the CBD. It's time we stop talking about cannabis use and start regarding it…

The THC levels in Canadian cannabis is f'd. Of all the things, I wish the gov. had put mandates that there must be a minimum level of CBD and maximum level of THC. It's bonkers.

Re: Cannabis use disorder and subsequent risk of depression and bipolar disorder

#87

Post by thsksbd »

eep_social wrote: post #65
l33t7332273 wrote: post #33

Earlier quoted context omitted.

What is the health justification for banning caffeine?

I was going over the top because gp is insinuating a moral argument rather than a health argument based on their interpretation of a bad headline. Cannabis Use Disorder is not the same as occasionally puffing a doobie with Alice on the weekend. > Caffeine starts off as a physical addiction unlike marijuana. Caffeine also does not require a lot of use from the substance in order to become physically addicted, unlike m…

And aside from the jitters, what harm does caffeine cause?

Does it cause break downs in families and car fatalities like alcohol?

Does it trigger latent schizophrenia in susceptible individuals like canabis?

Does it create zombies like whatever it is they're consuming in San Fran?

Re: Cannabis use disorder and subsequent risk of depression and bipolar disorder

#88

Post by ForestCritter »

teen wrote: post #31
daft_pink wrote: post #12

Earlier quoted context omitted.

I don't think people should be put in jail for cannabis. However, we shouldn't be devoting our tier 1 retail space or having startups with massive advertising budgets pushing it. It should be sold as a generic drug by pharmacies that make most of their business from other drugs not dispensary entrepreneurs creating massive retail brands like alcohol.

it's def not as bad as alcohol... considering alcohol causes drunk driving, liver issues, obesity, stomach cancer, domestic violence

Regular Marijuana use has a high domestic violence rate.
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