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Cheap antidepressant shows promise treating early Covid-19

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Re: Cheap antidepressant shows promise treating early Covid-19

#81

Post by sdhfjg »

nuerow wrote: post #74
sdhfjg wrote: post #67

Earlier quoted context omitted.

>"Alternative medicine" like ivermectine or hydroxychloroquine have no scientific, properly studied basis for being used. When a medical doctor prescribes a drug for a purpose that is currently being studied scientifically, that is not "alternative medicine". Ivermectin is still being studied. Hydroxychloroquine was emergency authorized by the FDA.

> When a medical doctor prescribes a drug for a purpose that is currently being studied scientifically, that is not "alternative medicine". It really is, as there is absolutely no evidence it has any effect whatsoever and at best it only serves as a placebo. In short, it's snake oil. Worse: politically-motivated snake oil.

Are the people participating in the scientific studies of the drug participating in alternative medicine?

Re: Cheap antidepressant shows promise treating early Covid-19

#82

Post by mdp2021 »

Axios brief:

https://www.axios.com/covid-study-fluvoxamine-antidepressant...

it also refer as the original article in the Lancet as

https://www.thelancet.com/journals/langlo/article/PIIS2214-1...

--

Note: do not overlook

> only one patient in the fluvoxamine died, compared to 12 in the control group

Re: Cheap antidepressant shows promise treating early Covid-19

#83

Post by 6nf »

robertbarbe wrote: post #68
6nf wrote: post #65

Earlier quoted context omitted.

Ivermectin is approved for covid use in the UK and many other countries with good results and a large Oxford study is close to completion to add to the dozens of positive studies

No. Ivermectin is not officially approved in the UK for the treatment of COVID-19. Source from the government : https://www.gov.uk/government/publications/freedom-of-inform...

I was under the impression that it was approved in July and your source predates this but I could be wrong

What do you say to the multitude of positive studies though? https://c19ivermectin.com/ Are all of them wrong?

Re: Cheap antidepressant shows promise treating early Covid-19

#85

Post by [deleted] »

twofornone wrote: post #56
onion2k wrote: post #47

Earlier quoted context omitted.

I hope this isn't attacked, because this isn't an "alternative" drug. Things move from "alternative medicine" to being "medicine" when people do good, peer-reviewed science to actually study the effects and find them to be effective. "Alternative medicine" like ivermectine or hydroxychloroquine have no scientific, properly studied basis for being used.

>"Alternative medicine" like ivermectine or hydroxychloroquine have no scientific, properly studied basis for being used. There are more than 60 peer reviewed studies showing positive effect for ivermectin. Similarly the single trial that the media touted as "proof" that HCQ did not work administered what amounted to an overdose to terminally ill patients, in contrast to the recommended early/prophylactic regimen. Th…

[deleted]

Re: Cheap antidepressant shows promise treating early Covid-19

#86

Post by raffraffraff »

foota wrote: post #70
sdhfjg wrote: post #67

Earlier quoted context omitted.

>"Alternative medicine" like ivermectine or hydroxychloroquine have no scientific, properly studied basis for being used. When a medical doctor prescribes a drug for a purpose that is currently being studied scientifically, that is not "alternative medicine". Ivermectin is still being studied. Hydroxychloroquine was emergency authorized by the FDA.

Hydroxychloroquine seems like a weird example to bring up now, since it's been completely debunked. https://www.fda.gov/drugs/drug-safety-and-availability/fda-c...

I actually think it might be a good example because it highlights the distinction between "medicine" and "alternative medicine": approval for use. Many drugs have been approved for a use in the past, only to be superseded by better drugs or found to be dangerous or ineffective.

Take for example acetaminophen (aka paracetamol/tylenol): it is borderline ineffective, has been superseded by ibuprofen for almost all use cases, and the required dosage for its tiny effect is also very close to dangerous levels. Yet it is still the go-to drug of parents, GPs and hospitals for a range of ailments from the common cold to post-operative pain. "Good old paracetamol" is in every medicine cabinet in the Western world. I've told my folks a hundred times that it simply doesn't work, but they use it for pretty much any condition. Mum even gave it to her old dog. It's trusted like oxo cubes, Campbell's soup or a nice cup of tea. And that's why it's the foremost cause of acute liver failure in the Western world. While it hasn't had it's approval removed yet, I wouldn't be surprised if it did some day, and I doubt it would be approved today if it were being introduced.

Even so: is it still very much "medicine", not "alternative medicine".

Re: Cheap antidepressant shows promise treating early Covid-19

#87

Post by SkittyDog »

jimbojet wrote: post #77
SkittyDog wrote: post #71

Earlier quoted context omitted.

All studies have some level of risk for bias... But that doesn't mean all studies have the same level of risk. The essay you linked is very good, but it's actually illustrating my point... The mouse study ran into bias problems because they had to go and directly measure something in nature, and then turn that into a number. That introduces several opportunities for error. But this SSRI/COVID study isn't doing that.…

You sound like you just took a stats 101 class and now are bragging to a bunch of adults about how much you learned in stats 101. Sincerely, someone working in the field for last 7 years.

Sounds like I don't know nearly as as you... I minored in stats 20+ years ago, but since then I do a lot more arguing about stats than actually using them for work.

You're kinda right about one thing, though... I am definitely talking down to OP, and a couple of other folks.

I'm frustrated. There are real problems in how science uses statistics, and it sounds like OP & co have heard about those problems. But the way they talk about this study, they're just throwing crap against the wall to have something to say. They don't really seem to understand the problems they're talking about, or how those problems apply to the study we're currently talking about.

I should change my attitude, and stop taking out my frustrations on these folks. If they're wrong, I'm probably not going to change their minds by insulting them.

Re: Cheap antidepressant shows promise treating early Covid-19

#88

Post by bsaul »

_huayra_ wrote: post #45
woodruffw wrote: post #10

Earlier quoted context omitted.

SSRIs are pretty serious, which is why you should probably just get vaccinated instead.

It's so strange how people are looking to truly foreign substances / drugs (from ivermectin to bleach to SSRIs now) compared to a vaccine, which is basically just a bunch of mRNA and a few preservatives. That is, a bunch of stuff that is basically already floating around in our bodies / cells.

i guess it's just natural distrust of anything that's new (mrna vaccines are most certainly a first time here). And tbh i find this suspicion quite reasonable.

Re: Cheap antidepressant shows promise treating early Covid-19

#89

Post by trevorishere »

wnkrshm wrote: post #60
woodruffw wrote: post #10

Earlier quoted context omitted.

SSRIs are pretty serious, which is why you should probably just get vaccinated instead.

Are they really? As someone who takes SSRIs after trying out more 'serious' alternatives for ADHD-related depression (e.g. slow release stims which are bona-fide narcotics), SSRIs are treated like candy and the first treatment option it seems to me.

SSRIs can induce undiagnosed Bipolar or SSRI-induced Bipolar disorder; in certain cases with rapid cycle.

It’s not fun.

Re: Cheap antidepressant shows promise treating early Covid-19

#90

Post by prox »

lettergram wrote: post #46

Glad to see this being spoken about! I’ve been assisting with data analysis for an eclectic group of people (who funded this study). Been really disheartening to watch the politics around alternative treatments. Personally, I expect this to be attacked as well, but am hopeful! The stuff really does seem effective, particularly when combined with other drugs...

If it’s a good study, you probably want it to be scrutinized. If it holds up in other studies that it works, congrats, we just did science! If it doesn’t, it’s just a belief that it works.
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