Furthermore Node has its own maintenance/risk issues in production systems (think permissions), and Deno reduces those with custom built runtimes.
I cannot see it replacing Node though. Node has created a vast ecosystem that includes modules (npmjs), client side bundlers (eg webpack), serverside frameworks (eg express), etc. But because Deno is solving some of the issues for those who run sensitive code in production (eg Lambda functions) it'll most likely gonna become another VM on the public cloud providers' list.
All in all Javascript interpreter is becoming something like a JVM. Everyone wants to use it but without writing vanilla Javascript.