81–90 of 112 posts
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dang really needs to get YC to develop an AI that can automatically add /s to ironic comment.
Or people could work on their ability to identify normal human modes of speech.
Strange way to word the two patient types: vegans as opposed to omnivores. Vegans are still omnivores, they just stopped eating animal products because of beliefs. I also smelled once a vegan cake. It's a medical miracle they can survive on such a diet.
> Vegans are still omnivores, No they aren't. From New Oxford English Dictionary: > omnivorous > adjective (of an animal or person) feeding on a variety of food of both plant and animal origin.
A human may choose to walk on all fours because they're insane, but they will still be a biped.
Not a surprise. Collagen is important for healing skin wounds, and vegans get none from their diet. (Collagen is just a protein, so it can be generated by the body, but it's easier for the body to simply take collagen from dietary sources.)
Do you have a source for this? As far as I know, there is no way for the body to uptake and employ collagen directly. It needs to be broken down into smaller peptides, absorbed, and rebuilt, just like any other protein.
We know that the body can use collagen without digesting it first because collagen masks are used to heal burn victims. See, for example: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565829/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081477/
Collagen is a protein. It is made up of several "peptides" referred to as "collagen peptides." When it is first digested, collagen is broken down into collagen peptides in the gut. The type of collagen determines the ratios of these peptides. Most, but not all of these collagen peptides get further broken down into amino acids in the gut. (Contrast to whey, which gets entirely broken down into amino acids.) However, a significant portion of collagen peptides can survive digestion, or leave the gut before they are digested. (Up to 10%, depending on the original source of the collagen.) The body can utilize these peptides directly to repair skin, because skin is mostly made of...collagen. The presence of collagen peptides simply lets the body go straight to creating collagen without having to wait while peptides are created from amino acids. (The body will still do that, but it's like starting a construction project with supplies on hand vs having to wait for supplies to arrive or be built.)
Not a surprise. Collagen is important for healing skin wounds, and vegans get none from their diet. (Collagen is just a protein, so it can be generated by the body, but it's easier for the body to simply take collagen from dietary sources.)
>it's easier for the body to simply take collagen from dietary sources. Digestion doesn't work like that. Any ingested collagen is broken down to amino acids like all other proteins. Then the amino acids are re-polymerized into collagen.
Most, but not all collagen is broken down into collagen peptides in the gut. Most of those collagen peptides are then broken down into amino acids. But not all collagen peptides are broken down, and the peptides that remain can enter the bloodstream where they can be utilized as needed.
(The collagen that doesn't get broken down in the gut tends to come out the other side of the digestive tract intact, because unlike collagen peptides, collagen is too large to enter into the bloodstream and there are no organs after the intestines that can make direct use of collagen.)
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> Given that and the already-existing ability to create collagen/gelatin in a lab that's suitable for vegans, I've always wondered why nobody has managed to get it to market as a food. Outside of some pastry applications (eg. mirror cake glazing), it's pretty much only used for Jell-O and aspic, neither of which are particularly trendy at the moment. There's gelatin and collagen in soups as part of making broth, but…
Huge demand for collagen powder as a beverage additive lately though. Could definitely be a real opportunity.
https://www.fooddive.com/news/nestle-to-acquire-majority-sta...
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Do you have a source for this? As far as I know, there is no way for the body to uptake and employ collagen directly. It needs to be broken down into smaller peptides, absorbed, and rebuilt, just like any other protein.
Yes, I should have been more specific that collagen gets broken down into collagen peptides. I didn't think I needed to be that specific since it's like the difference between Calorie and calorie (i.e., the distinction is not relevant to the discussion on hand). We know that the body can use collagen without digesting it first because collagen masks are used to heal burn victims. See, for example: https://www.ncbi.nl…
There is not good evidence that peptides larger than 2-3 amino acids can be absorbed into circulation via the gut in more than trace quantities (1). Digested collagen will be rich in certain amino acids (glycine and proline in particular), but calling something as small as a di or tripeptide a "collagen peptide" seems like an oddly arbitrary choice. I am a medical student with significant background in biochemistry, so please don't feel the need to dumb it down for me when you explain.
1. https://www.cambridge.org/core/journals/nutrition-research-r...
When I was younger and training very heavily in some sports, I experimented a bit with different diets. Bottom-line the more meat heavy my diet, the faster I would heal from injuries -- radically so. For a while I went on a low-carb diet and ate a very heavy animal protein diet. I shed pounds, had absolutely unstoppable stamina, had far fewer injuries, stretching improved, basically never bruised, and healed from spo…
I lift heavy about 4x week. A lower-carb calorie-restricted diet makes me more alert and focused. On the other hand, I sleep like shit, my anxiety levels skyrocket, and I also feel moodier, particularly in the mornings. I also lose strength fairly quickly. Eating at a surplus with carbs makes me more lethargic, lazy and less focused, but I sleep far better, and I’m in a happier, more social, mood. And of course I can…
When I was younger and training very heavily in some sports, I experimented a bit with different diets. Bottom-line the more meat heavy my diet, the faster I would heal from injuries -- radically so. For a while I went on a low-carb diet and ate a very heavy animal protein diet. I shed pounds, had absolutely unstoppable stamina, had far fewer injuries, stretching improved, basically never bruised, and healed from spo…
Did you ensure that you maintained protein level when you went vegan/vegetarian? It's easy to eat much less protein if you aren't careful.
Earlier quoted context omitted.
Do you have a source for this? As far as I know, there is no way for the body to uptake and employ collagen directly. It needs to be broken down into smaller peptides, absorbed, and rebuilt, just like any other protein.
Yes, I should have been more specific that collagen gets broken down into collagen peptides. I didn't think I needed to be that specific since it's like the difference between Calorie and calorie (i.e., the distinction is not relevant to the discussion on hand). We know that the body can use collagen without digesting it first because collagen masks are used to heal burn victims. See, for example: https://www.ncbi.nl…
Do you have a source where I can read more about this?
What's the point of having a better looking scar if you're more likely to get colon cancer? Also, given that study itself measured Iron and B12, supplementing Iron and B12 may help scar healing w/o the (red) meat eating downside.