The sticking point for me is the way tools like uv and poetry build everything around the idea of a "project". I don't want a separate environment for every project, and I don't want to start by creating a project. I want to start with an environment that has stuff in it, and I start fiddling around, and gradually something comes together that eventually will be pulled out into a separate project. From what I can see…
What you describe I think is what most other people hate the most about python. The fact that everything pollutes the global environment, which then becomes a mess of things depending on various versions, which also ends up breaking tools included in the OS and suddenly your whole system is effed.
Treating python as a project level dependency rather than a system level dependency is just an excellent design choice.