Hacker News Board Hacker News, browsed like a classic message board
Live data from Hacker News

US agencies call for pause in Johnson & Johnson vaccine

bbc.co.uk

Post reply on HN
Print view View original

751–760 of 1001 posts

Re: US agencies call for pause in Johnson & Johnson vaccine

#751

Post by thehappypm »

UncleOxidant wrote: post #309

John Campbell suggested on his video the other day that perhaps this is happening because some injectors are not aspirating. What that means is that when an intramuscular injection is given you want to ensure that it goes into the muscle and not into a vein. So the proper way to do this is for the person doing the injection to first pull out the syringe (after it's been stuck into the arm) a bit to make sure there's…

Any theory on why this is occurring needs to have a solid explanation for why women under 55 are suffering this effect more than anyone else. Does John Campbell have one?

Re: US agencies call for pause in Johnson & Johnson vaccine

#752

Post by hnburnsy »

From the CDC, updated today...

"Over 189 million doses of COVID-19 vaccines were administered in the United States from December 14, 2020, through April 12, 2021. During this time, VAERS received 3,005 reports of death (0.00158%) among people who received a COVID-19 vaccine."

https://www.cdc.gov/coronavirus/2019-ncov/vaccines/safety/ad...

Re: US agencies call for pause in Johnson & Johnson vaccine

#753

Post by thehappypm »

jjk166 wrote: post #331

6 cases in 7 million doses over 3 months is exactly the rate that CVST would normally be expected at. While that doesn't mean we shouldn't investigate, it does mean there is no reason to be alarmed at this time. > Cerebral venous sinus thrombosis is rare, with an estimated 3-4 cases per million annual incidence in adults. While it may occur in all age groups, it is most common in the third decade. 75% are female. [0]…

People need to accept that this is a real effect. Denying it isn't helping anyone. It's happening, it's rare, but it's happening.

Re: US agencies call for pause in Johnson & Johnson vaccine

#754

Post by Pyramus »

chemeng wrote: post #693
robbiep wrote: post #374

Earlier quoted context omitted.

If you’re doing the calf exercises to ward off a DVT, (and not to just stretch your strained calf!) you may be barking up the wrong tree. The preliminary theories (backed by the thrombocytopaenia) are that, if there’s a vaccine induced thrombosis with thrombocytopenia, it is probably immune-mediated (similar to HITT - heparin induced thrombocytopenia and thrombosis). And then there’s some weird thing that makes them…

Agreed, I don't think anyone knows clearly what is happening. Some additional points that are related. Thrombocytopenia has been a known complication of adenovirus vectors that researchers have worked to overcome in recent decades. These incidents mirror HITT (women are at higher risk for HITT) and seem to be happening in the timeperiod where IgG titers spike post vaccination. To me this indicates it's not unlikely s…

Just want to add that this is not a new theory and has been circulating in medical circles for roughly a month [1]. There is also the hope that when it happens it can be diagnosed and treated.

[1] https://twitter.com/LJohnsdorf/status/1371721321336475651 (in German)

Re: US agencies call for pause in Johnson & Johnson vaccine

#755

Post by savanu »

dheera wrote: post #746
e9 wrote: post #745

Earlier quoted context omitted.

This is not full story. 65% efficacy against symptomatic COVID-19 but 100% efficacy against death and hospitalization due to COVID-19. So there is real benefit to it.

Yes, but 65% efficacy still means that 1/3 of the vaccinated people will continue to be spreaders, which doesn't sound great, especially if that allows the virus to spread and evolve into a harsher variety.

The different efficacy rates of the vaccines do not directly imply anything about spreading covid.

A vaccinated person can have no symptoms of covid and still be spreading (This may or may not be true).

Folks are still studying how effective the vaccines are at preventing spread.

Re: US agencies call for pause in Johnson & Johnson vaccine

#756

Post by vmladenov »

ironmagma wrote: post #666
thelean12 wrote: post #645

Earlier quoted context omitted.

I'm not insisting that a claim is true just because an authority says it is. You can't just bring up "appeal to authority" and call it a day. I'm insisting that the average unqualified individual should not think they have a better chance of being correct over the authorities in question. There's no other rational option for unqualified individuals than to listen to medical authorities unless you have a medical degre…

There are actually a lot of reasons to be skeptical of experts — the same as why you should be skeptical of anyone. Appeal to authority has a contrapositive: the disappeal to lack of authority. The arbitrary person can be right just as much as the expert can. The whole point of logic and reason is that it’s about facts, not the people. Critically the problem with your reasoning is the last sentence. No, you do not ne…

Isn’t that inverse, not contrapositive? Here’s how I’m understanding it:

> appeal to authority

authority -> trust

> disappeal to lack of authority

not authority -> not trust

The contrapositive of the first proposition would be

not trust -> not authority

which is a rather different claim.

Re: US agencies call for pause in Johnson & Johnson vaccine

#757

Post by kazinator »

savanu wrote: post #755
dheera wrote: post #746

Earlier quoted context omitted.

Yes, but 65% efficacy still means that 1/3 of the vaccinated people will continue to be spreaders, which doesn't sound great, especially if that allows the virus to spread and evolve into a harsher variety.

The different efficacy rates of the vaccines do not directly imply anything about spreading covid. A vaccinated person can have no symptoms of covid and still be spreading (This may or may not be true). Folks are still studying how effective the vaccines are at preventing spread.

Keep in mind that a door handle is completely immune to Covid and can be spreading it.

Re: US agencies call for pause in Johnson & Johnson vaccine

#758

Post by dheera »

savanu wrote: post #755
dheera wrote: post #746

Earlier quoted context omitted.

Yes, but 65% efficacy still means that 1/3 of the vaccinated people will continue to be spreaders, which doesn't sound great, especially if that allows the virus to spread and evolve into a harsher variety.

The different efficacy rates of the vaccines do not directly imply anything about spreading covid. A vaccinated person can have no symptoms of covid and still be spreading (This may or may not be true). Folks are still studying how effective the vaccines are at preventing spread.

Okay, but until they're done studying, maybe let's just make more of the 94% vaccine using J&J's facilities?

Re: US agencies call for pause in Johnson & Johnson vaccine

#759

Post by InitialLastName »

captainredbeard wrote: post #224
hn8788 wrote: post #91

So this past year the government has been willing to let unemployment, suicides and drug overdoses jump due to isolation and loneliness caused by lockdowns, child abuse to skyrocket and mental health to plumment due to schools being kept closed, all because we needed to stop covid at any cost. Now one person dies out of almost 7 million who received the vaccine, and we need to stop administering the J&J vaccine "out…

Government over-reactions to COVID19 have been disastrous. There would have been an economic hit for sure but things would have returned to near normal by August 2020 if they had respected freedom (or if people had disobeyed in mass).

How many dead people would that "normal" have been worth to you?

If, instead, people had behaved responsibly in mass and we had used the time we got from that to establish coherent contact tracing and testing, things would have returned to normal by August as well, only without many the deaths your way would cause.

Re: US agencies call for pause in Johnson & Johnson vaccine

#760

Post by thelean12 »

dheera wrote: post #746
e9 wrote: post #745

Earlier quoted context omitted.

This is not full story. 65% efficacy against symptomatic COVID-19 but 100% efficacy against death and hospitalization due to COVID-19. So there is real benefit to it.

Yes, but 65% efficacy still means that 1/3 of the vaccinated people will continue to be spreaders, which doesn't sound great, especially if that allows the virus to spread and evolve into a harsher variety.

At this stage, getting as many people to near 100% death avoidance and with some immunity is the goal.

We're not at a stage yet when we can play favorites. It'll be a long time before we have the supply to prefer one over the other (except maybe in the US where there will be enough mRNA vaccines to go around).

Post reply on HN