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Ozempic shows anti-aging effects in trial

trial.medpath.com

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Re: Ozempic shows anti-aging effects in trial

#741

Post by cthalupa »

b112 wrote: post #546
glp1guide wrote: post #506

Earlier quoted context omitted.

Interesting -- would love to hear anything more you have to share! The research numbers would suggest that Reta was top, results wise. Any other significant differences you felt/noticed? Also, do you find Tirz to be an imiprovement over Sema?

The problem with online is, were all those Reddit posts you saw just astroturfers? And the whole point, to drum up funding for Reta? Or buzz? One person can easily turf as 1000 too, posting from a few accounts every day over the course of a year.

The studies for Reta are showing gangbusters results. And it's being developed by Eli Lilly, so they hardly need funding.

I swapped to Reta from Tirz and have found it to be a significantly better option myself.

Re: Ozempic shows anti-aging effects in trial

#742

Post by cthalupa »

radiofreeeuropa wrote: post #50
Someone1234 wrote: post #39

Earlier quoted context omitted.

Generic Semaglutide is already produced on a massive scale throughout the world. However, it is unlawful to import and sell and will remain so until 2032 in the USA. In other markets, where it is under patent, it is significantly cheaper than the $500/month or more in the US currently. For example in the UK it is roughly $150/month USD privately (i.e. not through the NHS). In China it will be out of patent within two…

There's a whole little online subculture of people in the US importing the precursors and making it themselves at home for dirt-cheap. I gather it's extremely easy and basically fool-proof, as far as producing the desired drug and not producing some other, undesired drug. Much easier than, say, home-brewing beer. The risk is all in contamination, which presents a vector for infection. [EDIT] I don't mean to downplay…

It's not the precursors, it's the freeze dried powder form of the drug plus an excipient, generally mannitol.

You just reconstitute it with BAC water and inject it.

Re: Ozempic shows anti-aging effects in trial

#743

Post by vidarh »

backscratches wrote: post #484
op00to wrote: post #204

Earlier quoted context omitted.

You’re a fool. “Pull out” does not protect against pregnancy or STDs. Pre-ejaculate can have viable sperm in it.

pre ejaculate contains zero sperm if you havent fully ejaculated previously. there is no mechanism for sperm to be released during preejaculation.

[dead]

Re: Ozempic shows anti-aging effects in trial

#744

Post by ifyoubuildit »

sumeno wrote: post #717
ifyoubuildit wrote: post #683

Earlier quoted context omitted.

As I understand it, species that are really good at healing from injuries are more likely to develop cancer. So evolution has to optimize for survival via healing vs survival via not getting cancer. Some people probably do come at it from the moral angle. But there are good reasons to assume that this time isn't different, that there is indeed no free lunch. Thankfully, everyone is free to make that risk assessment t…

It seems like you really missed the point. Of course there are reasons we still get cancer, just like there are reasons people get fat. Evolutionarily people are way more likely to die of being under nourished than over, so the body packs on fat when it can. Evolution did not optimize for 2025 > Some people probably do come at it from the moral angle. But there are good reasons to assume that this time isn't differen…

> It seems like you really missed the point

Yeah, I guess I don't really know what your point was if it wasn't to ask why we get cancer. Maybe that's my fault?

> A medication may have side effects

... beyond the initially understood ones. Tylenol has been around for a long time. When it first came out, people were probably popping it like candy until they realized the limits, and now it's pretty well understood.

And who cares if people are "clutching their pearls"? What harm does that do?

> Is someone trying to force you to take Ozempic?

Not yet, but I won't be surprised if people start pushing for it. Think about things like soda laws and seatbelt laws. If my being obese is costing you tax or insurance dollars and we have this magic pill, it's only a matter of time before the machine does its thing.

Re: Ozempic shows anti-aging effects in trial

#745

Post by astura »

fortran77 wrote: post #274
glp1guide wrote: post #269

Earlier quoted context omitted.

We think obesity is basically going to be gone in This is going to accelerate when every one and their mother (with industrial capacity) starts making generic Ozempic/Wegovy (Semaglutide) next year due to Canada's patent protection lapse[0]. https://glp1.guide/content/novo-nordisk-patent-protections-l...

I think that, just like with stomach reduction surgery, people are going to find a way to overeat and gain weight while taking Ozempic too.

Ozempic alters the rewards system, so if it's working you don't want to overeat, not just that you physically can't.

Re: Ozempic shows anti-aging effects in trial

#746

Post by eggsboenk »

spauldo wrote: post #387
eggsboenk wrote: post #207

Earlier quoted context omitted.

I don't understand why comments about pharmaceutical companies and their incentives are accepted here, but if you mention the same in the context of vaccines, you're labeled a conspiracy nut.

There is a diverse set of opinions on this site. We don't all think the same. Also, there's a distinction you're overlooking. Not trusting big pharma isn't the same thing as not trusting medicine. Big pharma will happily sell us drugs that work - it's the most profitable thing they do. You just can't trust them blindly, which is why regulation is important. In the case of vaccines, they've proven effective over a ver…

Healthy suspicion for the mRNA vaccines was not really accepted, was it?

Re: Ozempic shows anti-aging effects in trial

#747

Post by glp1guide »

b112 wrote: post #546
glp1guide wrote: post #506

Earlier quoted context omitted.

Interesting -- would love to hear anything more you have to share! The research numbers would suggest that Reta was top, results wise. Any other significant differences you felt/noticed? Also, do you find Tirz to be an imiprovement over Sema?

The problem with online is, were all those Reddit posts you saw just astroturfers? And the whole point, to drum up funding for Reta? Or buzz? One person can easily turf as 1000 too, posting from a few accounts every day over the course of a year.

This is a valid concern but the subreddits I'm thinking about are not quite that -- no one is selling or trying to push you to some distributor, it's a lot of the bodybuilding/peptide crowd. More like walking into a classic forum thread than modern reddit. You can tell by the comments.

Re: Ozempic shows anti-aging effects in trial

#748

Post by nurettin »

Fargren wrote: post #493
anal_reactor wrote: post #407

Earlier quoted context omitted.

I think Ozempic is just a symbol of what modern life looks like. Obesity is a problem that 100% could be solved with a cultural shift (see Japan), but instead we decide to use medicine. It's like, humanity at large grew such big brains because there was evolutionary pressure to be intelligent, but now we're using intelligence to remove that pressure. Which would make sense if we redirected that intelligence to someth…

The way Japan "solves" obesity is quite cruel on those it does not work for. Overweight natives are not treated kindly. I think creating a medicine to make this easier is a moral good, and a sign of kindness and intelligence. Hopefully the aliens also agree.

Who does it not work for? (it being light eating and exercise, not some draconian torture)

Re: Ozempic shows anti-aging effects in trial

#749

Post by ponector »

wongarsu wrote: post #563
kashunstva wrote: post #519

Earlier quoted context omitted.

> The body is a marvelous machine, but it is far from a perfect or intelligent design. And I think that we can only expect the process of evolution through natural selection to operate on traits that cause differential survival of individuals before reproduction. All sorts of new traits acquired through random mutation and recombination that only affect individuals after typical reproductive years will exist even whi…

Yet women have a longer lifespan despite shorter reproductive years. If in a hunter-gatherer society most people stop reproducing after 40 (not entirely realistic, but bear with me), me being alive and fit at 45 can still improve the survival of my genepool. I can hunt meat and gather plants to make sure my children and grand-children are well-fed and able to produce plenty of offspring, carrying my genes on. I can b…

To increase chances of survival of the population you need just an extra 10y after the end of reproduction to grow last child, no more.

Re: Ozempic shows anti-aging effects in trial

#750

Post by Majromax »

wongarsu wrote: post #563
kashunstva wrote: post #519

Earlier quoted context omitted.

> The body is a marvelous machine, but it is far from a perfect or intelligent design. And I think that we can only expect the process of evolution through natural selection to operate on traits that cause differential survival of individuals before reproduction. All sorts of new traits acquired through random mutation and recombination that only affect individuals after typical reproductive years will exist even whi…

Yet women have a longer lifespan despite shorter reproductive years. If in a hunter-gatherer society most people stop reproducing after 40 (not entirely realistic, but bear with me), me being alive and fit at 45 can still improve the survival of my genepool. I can hunt meat and gather plants to make sure my children and grand-children are well-fed and able to produce plenty of offspring, carrying my genes on. I can b…

> Yet women have a longer lifespan despite shorter reproductive years.

After industrialized nations have reduced both maternal mortality and violent death (warfare) to small fractions of their pre-modern levels. The life tables of 1500, 500, or 5000 BC would look very different than their modern versions.

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