741–750 of 1001 posts
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If the consequence of not taking it is death, I think people would run to the front of the queue, though.
But that's just it, there's less than a 2% chance of dying even if you get COVID.
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Who is the market for this? The assumption is that you give it ASAP and people want to take it. If people aren’t interested in vaccinations they may not want it either, and the vaccines are already very effective at preventing these issues.
Unfortunately, it's the opposite. Anti-Vaxx people seem to absolutely love non-vax treatments. I don't know if the rationalization is sound, but I'm not sure it's really that. The anti-vaxx stigma pre-COVID I think has had it's toll. The notion of 'government pushing you to take something' as well. Whereas, 'you get sick, you take a pill' is an easy concept. My fear is that a lot of people won't bother with a vax if…
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The mRNA vaccines do not, and never have, reduce the spread of the virus from one infected person to someone else. The only thing they do is reduce symptoms. That has been known from clinical trials. Everything else is a talking point not based on a peer reviewed scientific study. Or if you think you have a study that refutes this, please post.
> The mRNA vaccines do not, and never have, reduce the spread of the virus from one infected person to someone else That's simply not correct.
"fully vaccinated individuals with breakthrough infections have peak viral load similar to unvaccinated cases and can efficiently transmit infection in household settings, including to fully vaccinated contacts." [1]
[1] https://www.thelancet.com/journals/laninf/article/PIIS1473-3...
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Unfortunately, it's the opposite. Anti-Vaxx people seem to absolutely love non-vax treatments. I don't know if the rationalization is sound, but I'm not sure it's really that. The anti-vaxx stigma pre-COVID I think has had it's toll. The notion of 'government pushing you to take something' as well. Whereas, 'you get sick, you take a pill' is an easy concept. My fear is that a lot of people won't bother with a vax if…
I think the main difference is one has to necessarily take on vaccine risk without catching covid, so you balance chance of vax complications vs chance of getting covid multiplied by chance of getting bad case of covid. So 1 * P(bad vax) vs P(getting covid) * P(bad covid case). While most of other proposed treatments are after you already got it. So P(bad side effects) vs 1 * P(bad covid case). Depending on your prio…
Thankfully that risk is tiny.
> Also, if the new pill ends up as effective as they say it is, there is no reason to push for 100% vax uptake anymore -- it would turn covid into a slightly more dangerous cold.
No, vaccination remains far cheaper. Mass vaccination also reduces the risk of mutation, and of infection others.
If everybody gets vaccinated AND this anti viral is widely available for those infected, COVID will be well and truly deranged.
> Pfizer’s phase 2/3 trial randomized non-hospitalized adult COVID-19 patients who were at high risk of progressing to severe illness to receive placebo or Paxlovid, a combination of the protease inhibitors PF-07321332 and ritonavir. The efficacy analysis is based on 1,219 patients. One noteworthy feature is the newness of this drug: > PF-07321332 was developed from scratch during the current pandemic. It’s a reversi…
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By now you should have noticed that you're not "getting back on with your lives" no matter how good a boy you are and how many freedoms you give up. You should have resisted this from the start, this is your choice.
Frankly given the work I've done demonstrating the anti science direction policy has taken and the work I've done to call out the bad "science" since the start you should be thankful for the work I've done. As for further "resistance" as soon as the 5G anti-vax nutters started i started looking out for me by putting money in the bank. My response from idiots insulting me over the last 2 years is too stop carrying abo…
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That it's unethical to continue giving half the participants a placebo makes sense. I am curious though: do they ever continue with the trial, with the patients on the actual drug? Might that be useful for monitoring rare-ish side effects, even if the drug is highly effective?
I believe they've only halted recruiting for the trial, not the trial itself. The Pfizer CEO this morning also said they're continuing with plans for two other trials starting soon, which is in people with non-co-morbidities, and to household contacts of confirmed cases.
> Pfizer’s phase 2/3 trial randomized non-hospitalized adult COVID-19 patients who were at high risk of progressing to severe illness to receive placebo or Paxlovid, a combination of the protease inhibitors PF-07321332 and ritonavir. The efficacy analysis is based on 1,219 patients. One noteworthy feature is the newness of this drug: > PF-07321332 was developed from scratch during the current pandemic. It’s a reversi…
> Less than two years from lab to clinic is highly unusual. If approved, I believe this would be the fastest lab-to-approval for a small molecule drug in the history of the FDA. It's sad that we all know people are going to use this fact to reject taking this medication while still chugging horse paste.
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Why are you linking to such a page? This isn't a trustworthy source.
Oh? It only links to dozens of peer-reviewed journals and studies. Totally suspect. Can't win all the jab religion followers, it seems ¯\_(ツ)_/¯
Then they could actually use a methodology that makes sense.
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Frankly given the work I've done demonstrating the anti science direction policy has taken and the work I've done to call out the bad "science" since the start you should be thankful for the work I've done. As for further "resistance" as soon as the 5G anti-vax nutters started i started looking out for me by putting money in the bank. My response from idiots insulting me over the last 2 years is too stop carrying abo…
>5G anti-vax nutters I have yet to meet anyone who's unvaxxed because they think of some 5g conspiracy. I smell corporate media type elitism in your comment.
I'm not going to ban you right now, but please review the site guidelines and stop breaking them.