I'm on 12 years of self hosting email and counting. Once every so often, I do end up being blocked, usually by Outlook and once by Yahoo. I'm in their 'sender program' and they still don't actually bother to contact postmaster@, but a few emails is usually enough to unblock the block within 24h. Agree with a sibling comment that many major providers fail to operate the SPF/DKIM/DMARC tools they insist you do. Each to…
To host anything beyond those protocols and/or on more powerful hardware is often counter productive.
The problem is getting the ports opened, you need to fight for that right even if it makes spam worse in the short term.
Fight for external IP, ports and static IP in that order.