By tolerating the loss of two disks, do you mean raidz2 or do you mean 3-way mirror? Raidz2 is not fast. In fact, it is slow. Also, it is less reliable than a two way mirror in most configurations, because recovering from a disk loss requires reading the entirety of every other disk, whereas recovering from loss in a mirror requires reading the entirety of one disk. The multiplication of the probabilities don't work…
Why not Raid 60 with Btrfs? It'll tolerate two disk loss with pro-active parity protection via btrfs and be faster and provide you with more disk space.
When I do a Google search, I want to see confirmed cases of fs lockups / data loss from fs bugs to be multiple years in the past. btrfs isn't there yet.
I like btrfs's ability to e.g. switch raid levels without offlining the array. I think it's promising. But I wouldn't trust my data to it tomorrow.