Since this thread will likely turn into people asking about Cloudfront performance, does anyone have any real-world experience with CloudFront vs. Rackspace with Akamai CDN? On paper the Rackspace one looks like a great performance/price alternative.
I don't know about Cloudfront vs Rackspace+Akamai, however, based on some quick tests I did a year ago, I seem to recall that Rackspace+Akamai didn't deliver the same performance as professional Akamai services. In my experiments, Rackspace+Akamai used different servers, often located farther away, than big Akamai sites. (If anybody has background information about this, I would be very interested to hear.)
"Rackspace uses 213 of Akamai's edge locations, selected especially for our customers' typical usage patterns, and designed to cover all major areas of the globe." http://www.rackspace.com/cloud/files/
Akamai has approximately 5 gazillion edge locations, so yes, it is a cut down version. It is still a lot more POPs than just about every other CDN, though this doesn't necessarily translate into performance.