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Ah, I was wondering the evolutionary reason why those genes would have gone dormant. Cancer is a sensible answer.
Dinosaur Predation damage? If you life fast, get eaten young, repairs are a waste.
It's just hidden by a feature flag. (Probably for a good reason)
Evolution is so smart.
Like the way slime molds solve mazes: explore every possible path in parallel, and push growth in all areas with greater nutrient gradients. Not by sensing any gestalt clues, like symmetries in the maze design.
Astoundingly stupidly smart.
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How do you know?
Because I'm a grownup who knows the difference between reality and make-believe.
Signed, 50 years an atheist.
Retina is a good example of this. Zebrafish can regrow damaged retina, but while mammals have the same stem cells (Muller glia), they dont repair the retina, but form scar tissue. There is a lot of research and I think they have managed to modify rat genome, so that their retina has showns some repair abilities. The problem is that it often causes tumors. I have other retina permanently damaged, and suffer from doubl…
This short video talks about telomere-snipping transcription factors that make seemingly-dead cells revert to normal or even to stem cells, but the factors only act when under artificially-maintained conditions: