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MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)

sciencedaily.com

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Re: MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)

#71

Post by throwforfeds »

throwaway12pol wrote: post #2

Unfortunately, I will probably never be able to try that for my GAD even if they confirm the positive effects due to stigma surrounding psychoactive drugs! Yay!

Do you mean it won't be legalized because of stigma, or you personally wouldn't try them because of stigma?

People that think psychedelics are evil are just closed minded people that probably need psychedelics in their life. You probably don't want to pay attention to what they think. If you're genuinely looking for healing there are plenty of people that practice psychedelic assisted therapy around the world that could help you take those first steps. It's underground, but not terribly hard to find with some online searching.

Re: MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)

#73

Post by motoxpro »

tim-projects wrote: post #21

I'd argue that the results might not be from the drugs but from the fact that they were heavily monitored by other humans. It's not the drugs that people with high anxiety need, it's people giving them attention and caring for them. These experiments need a control where they just take the drug and they don't have medical staff around.

This is exactly what the placebo is for. Same attention and care, no drug.

Re: MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)

#74

Post by dessimus »

throwforfeds wrote: post #43
goodmythical wrote: post #32

Earlier quoted context omitted.

Call me a luddite, but I'd personally honestly preferring knowing my chemist so that I can be relatively certain there's no 2-ci or whatever bs the kids are cutting with or straight up substituting these days. My understanding is that, today in the US (and other markets so far as I know), it is far easier to know a pharmacist than a genuine LSD chemist, though I am several years out of that particular market. Would b…

While I agree that I'd love to have a guarantee on purity, the way to do that is just to make LSD legal, rather than have some private equity backed pharma company tie up the supply. LSD should be a case like insulin or the polio vaccine, as it offers an immense amount of potential for the planet. Sure, if they want to make money by offering retreats in clinical settings for people too afraid to spend an afternoon wi…

Except just legalization is no guarantee of safety or purity. Look at the Vitamin Industry as an example. The general public thinks that manufacturers of those bottles in the vitamin aisle are required to follow the same standards set by the FDA as those in OTC pain relief in the next aisle over.

Re: MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)

#75

Post by cluckindan »

cassepipe wrote: post #57
throwaway12pol wrote: post #24

Earlier quoted context omitted.

Isn't that basically the same as them using a placebo? If just care has the same effect, then surely heavily monitoring them while providing a placebo drug should work.

The problem is you can very obviously tell that you have a placebo because nothing is happening. Some studies mitigate that issue by giving a microdose but then maybe only the microsose is necessary? It seems like a hard problem

Such studies typically use an active placebo, such as methylphenidate.

Re: MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)

#76

Post by ksaj »

tokai wrote: post #37
lelanthran wrote: post #19

Earlier quoted context omitted.

> The "surprising way" is by using a derivate of LSD. What's the difference between a derivate and a derivative? (I'm not being facetious, I'd really rather like to know)

MM120 is just a patented LSD. So its just a brandname LSD.

Exactly. The medical cannabis industry has been doing this right from the start. Thankfully they do tell you what strains they got their cultivar from, though.

Re: MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)

#77

Post by abrookewood »

tim-projects wrote: post #21

I'd argue that the results might not be from the drugs but from the fact that they were heavily monitored by other humans. It's not the drugs that people with high anxiety need, it's people giving them attention and caring for them. These experiments need a control where they just take the drug and they don't have medical staff around.

That's why we have placebos ... and double-blind studies ...

Re: MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)

#78

Post by cluckindan »

jijijijij wrote: post #46
goodmythical wrote: post #32

Earlier quoted context omitted.

Call me a luddite, but I'd personally honestly preferring knowing my chemist so that I can be relatively certain there's no 2-ci or whatever bs the kids are cutting with or straight up substituting these days. My understanding is that, today in the US (and other markets so far as I know), it is far easier to know a pharmacist than a genuine LSD chemist, though I am several years out of that particular market. Would b…

Yeah, of course that's all legit concerns and demands. However, I dislike the notion this "dangerous street drug" was graciously made to somethings "useful" and safe by the pharma industry. It's the same its always been. Especially around the time of its prohibition. I am calling out a pattern. It's a bit similar to pharma going into the jungle, taking some natural compound (possibly known to an indigenous tribe), mo…

Sandoz was the first to manufacture LSD under the product name Delysid.

Re: MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)

#79

Post by cluckindan »

catigula wrote: post #34

These psychedelic treatments always have substantial limitations, and this is no different; 1. Low volume cohort i.e. 40 participants per dose group 2. Industry sponsored study i.e. MindMed. 3. Think about it; how do you blind psychedelics? It's pretty obvious you're on one when you take it.

Let me guess: Those limitations are ”unscientific” in this context, but when the article is about the dangers of cannabis, they are suddenly okay?

Re: MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)

#80

Post by leoh »

butlike wrote: post #69
OutOfHere wrote: post #11

Earlier quoted context omitted.

No. That is a gross and deliberate mischaracterization in bad faith. Here is the full quote: > Side effects were generally mild or moderate and included hallucinations, visual distortions, nausea, and headache. It's important to note, these were more prevalent using the highest dosage -- which we will not be using since it was found to be no more effective.

More prevalent, not absent. As I understand it, anything that affects the 5HT2A receptor will induce a psychedelic state. Magnitude being dose-dependent.

>more prevalent using the highest dosage
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