71–80 of 217 posts
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Naproxen sodium is also a lot better, and is slightly safer than ibuprofen to take for extended periods. I had severe sciatica for the better part of a year, and the only thing that kept me somewhat functional was ~1000mg/day of naproxen, which isn’t great for you but would’ve been a lot worse if it had been ibuprofen (never mind opiates or something).
Earlier quoted context omitted.
> ibuprofen is better in every way. Taking ibuprofen (or other NSAIDs) long-term can wear away the stomach lining, causing ulcers. Acetaminophen is generally better tolerated to manage mild long-term pain than NSAIDs, as long as you don't overdose / take with alcohol.
Yes, you need to take it with food, but it won't cause liver failure.
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Naproxen sodium is also a lot better, and is slightly safer than ibuprofen to take for extended periods. I had severe sciatica for the better part of a year, and the only thing that kept me somewhat functional was ~1000mg/day of naproxen, which isn’t great for you but would’ve been a lot worse if it had been ibuprofen (never mind opiates or something).
Earlier quoted context omitted.
As with all things, the poison is in the dose. A tonne of incredibly useful medicine can kill you if dosed incorrectly.
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I suspect it will: There's statistical evidence from how Britain migrated its cooking gas systems away from carbon-monoxide-heavy mixes [0] indicating overall suicide-rates are sensitive to convenience and involve short-term periods of vulnerability. As contrasted to "if they really want to they'll find a way no matter what." [1]
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[0] https://www.npr.org/2008/07/08/92319314/in-suicide-preventio...
[1] That said, I wouldn't be surprised if there's a bimodal distribution lurking in there, between "depressed but otherwise healthy" versus "terminal diagnosis and chronic pain." The latter-group might not be deterred by inconvenience.
I've always had an (unreasonable?) dislike of Paracetamol/Tylenol ever since I found out it was the #1 cause of acute liver failure in the US. Liver failure is scary. https://en.wikipedia.org/wiki/Paracetamol_poisoning
Total culture shock for me, as in Europe the default for children is rectal ingestion (which is probably a culture shock as well for Americans). Any how, with pills it is much easier to avoid overdose.
Earlier quoted context omitted.
Same goes for icebaths, they reduce inflammation, which is the whole point of working out.
What about ginger? Because that apparently only downregulates COX-2 without affection COX-1 (most inflammation-reducing drugs affect both)
It's probably worth mentioning that this drug is called Acetaminophen in the US, and is the active ingredient in Tylenol and other over the counter medicines.
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The episode shows how even small overdoses of acetaminophen can cause fatal liver damage, while decades of FDA delays and confusing drug labeling left millions of Americans at risk.
I'm sure an untreated infection might be more upsetting.