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Aspartame aggravates atherosclerosis through insulin-triggered inflammation

sciencedirect.com

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Re: Aspartame aggravates atherosclerosis through insulin-triggered inflammation

#71

Post by HumanOstrich »

sleepyguy wrote: post #16

Peter Attia has covered this at some length. https://peterattiamd.com/what-are-the-side-effects-of-aspart... >While an excess of alcohol sugars can cause gastrointestinal distress (e.g., if you overdo it on these you can get diarrhea), in most people they do not cause secretion of insulin from the pancreas due to their distinct chemical structure (see figure of their structures, above). The same is true for the first…

False, read TFA. It says the opposite -- there are effects on insulin secretion and resistance for aspartame, saccharin, and sucralose. Only studies funded by the food industry say there is no effect.

Re: Aspartame aggravates atherosclerosis through insulin-triggered inflammation

#72

Post by HumanOstrich »

torben-friis wrote: post #14
teslabox wrote: post #2

Aspartame (1965) was approved by the US FDA in 1974/1981. This is commonly paired with acesulfame-K (1967) to provide sweetness in low-calorie drinks and sodas. Saccharin (1879) was the first artificial sweetener, followed by cylcamate (1937). Low calorie sodas (Tab, etc) using these sweeteners were introduced in the 1950’s and 1960’s. In the 1980’s diet sodas sweetened with the combination of aspartame and acesulfam…

Aspartame does not increase insulin, unless I'm not updated on the current scientific consensus. Also your idea is very american centric, diet sodas are mainstream around the world and most of those countries did not follow the us into the obesity epidemic.

You are definitely not updated on current scientific research. TFA discusses this.

Re: Aspartame aggravates atherosclerosis through insulin-triggered inflammation

#73

Post by loeg »

atombender wrote: post #69
loeg wrote: post #64

Earlier quoted context omitted.

"Ultra-processed" is just a retcon'd term circularly defined as any calorie dense, low satiety food you already have reason to believe is unhealthy.

Not really: https://en.wikipedia.org/wiki/Nova_classification .

Yes, really. Nova's definition is exactly what I'm describing earlier. Here is their own definition, from the wiki you linked:

> There is no simple definition of UPF, but they are generally understood to be an industrial creation derived from natural food or synthesized from other organic compounds. The resulting products are designed to be highly profitable, convenient, and hyperpalatable, often through food additives such as preservatives, colourings, and flavourings.

https://en.wikipedia.org/wiki/Ultra-processed_food

Re: Aspartame aggravates atherosclerosis through insulin-triggered inflammation

#74

Post by loeg »

Guzba wrote: post #66
loeg wrote: post #60

Earlier quoted context omitted.

Potato, potato. CICO is just physics, but "optimized flavor and marketing strategies" has had impact on the "CI" side of the equation.

It seems very different and critically important. Would we have a current obesity epidemic without "optimized flavor and marketing strategies"? Because if we would not, then that is the true cause and of fundamental public health importance. If we would have an obesity epidemic even without "optimized flavor and marketing strategies", then it is totally irrelevant.

Yes and no. I think there are two levers on the CI side of the equation and only one of them is hyper-palatability (optimized flavor); the other is simply cost. Food costs have fallen sharply, and that contributes to over-feeding. Hyper-palatability also contributes. It's not irrelevant, but not the only factor.

Re: Aspartame aggravates atherosclerosis through insulin-triggered inflammation

#76

Post by snapplebobapple »

techwiz137 wrote: post #48
butterlettuce wrote: post #40

Earlier quoted context omitted.

I was hooked on diet coke until one day I decided to take a break, and my tongue felt... weird. It felt slightly fizzy as if my brain was signaling that it was time to drink diet coke. On top of that, I felt lazy for a couple days. I'm glad I was that self aware because I stopped drinking it everyday. Maybe 1 or two a month.

I attempted this just recently, I went 12+hrs without caffeine intake and I had the worst, headache that wouldn't go away with regular pills. Basically very intense caffeine withdrawal.

That lasts for up to a week and then you are through. You should find a quiet week and suffer through once just to prove to yourself you can and to decide whether to consume agaib clean

Re: Aspartame aggravates atherosclerosis through insulin-triggered inflammation

#77

Post by profsummergig »

redwall_hp wrote: post #56
profsummergig wrote: post #23

Earlier quoted context omitted.

Why does capitalism not make people fat in Japan, France, Italy and Spain?

Japan's easy: only about 1-in-3 households in Tokyo (and presumably the other large cities, where the majority of people live, are similar) own a car. People walk and take trains to work or to go shopping or eat out. A half hour of walking can burn upwards of 100 calories. The typical diet is also relatively lower in bread (processed carbohydrates...with unnecessary added sugar in the US) and higher in protein. That…

> diet is also relatively lower in bread

I've wondered about about carb substitution. The rice, and the wheat noodles, why are they healthier? (I can understand rice somewhat: it's less processed, by certain definitions.)

Re: Aspartame aggravates atherosclerosis through insulin-triggered inflammation

#78

Post by [deleted] »

gruez wrote: post #65
roboror wrote: post #58

Earlier quoted context omitted.

The "zero sugar" version has sucralose

No? https://www.coca-cola.com/us/en/brands/coca-cola/products/ze... >CARBONATED WATER, CARAMEL COLOR, PHOSPHORIC ACID, ASPARTAME, POTASSIUM BENZOATE (TO PROTECT TASTE), NATURAL FLAVORS, POTASSIUM CITRATE, ACESULFAME POTASSIUM, CAFFEINE, STEVIA EXTRACT. Not sure how stevia got on there. The zero caffeine version (also on that list) doesn't have it. Nor does Amazon's listing https://www.amazon.com/Coca-Cola-Zero-Sugar-…

[deleted]

Re: Aspartame aggravates atherosclerosis through insulin-triggered inflammation

#79

Post by hedora »

pupppet wrote: post #13

How is there not a slam dunk answer to whether this 50+ year old incredibly popular ingredient is ok for us or not?

There’s strong evidence that all artificial (including “organic non-caloric”) sweeteners disrupt metabolic responses, leading to lethargy and more weight gain than a comparably sweet amount of sugar.

In addition to making you fat, most others have some other bonus side effects like causing cancer, migraines, screwing up gut microbes, etc.

Re: Aspartame aggravates atherosclerosis through insulin-triggered inflammation

#80

Post by ein0p »

profsummergig wrote: post #77
redwall_hp wrote: post #56

Earlier quoted context omitted.

Japan's easy: only about 1-in-3 households in Tokyo (and presumably the other large cities, where the majority of people live, are similar) own a car. People walk and take trains to work or to go shopping or eat out. A half hour of walking can burn upwards of 100 calories. The typical diet is also relatively lower in bread (processed carbohydrates...with unnecessary added sugar in the US) and higher in protein. That…

> diet is also relatively lower in bread I've wondered about about carb substitution. The rice, and the wheat noodles, why are they healthier? (I can understand rice somewhat: it's less processed, by certain definitions.)

Probably slower absorption. Bread really peaks blood glucose, and therefore insulin.
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