71–80 of 131 posts
I wonder if using something like Retinol, which is proven to improve skin and make it look tighter, younger, and get rid of blemishes, marks, and sun damage, could be paired with Ozempic to keep skin more healthy along with a good skin routine?
I'm sometimes reminded of a parable of an old lady who swallowed a fly...
Right, because 15 years ago nobody else lost any weight. GLP-1s and roux-en-Y are literally the only two treatments shown in clinical studies that cause people to lose weight and keep it off indefinitely.
Maybe the skin is saggy because there’s nothing under it, maybe not? But at least they won’t have a stroke, heart attack, cancer or type 2.
Chemo is going to make you look much worse.
The new category of patient is “person who successfully lost weight and kept it off without gastric bypass.”
[edit] if you think I’m exaggerating there’s a great study from 2023 that tracked how many people lost more than 5% body weight in a given year.
Answer: 1 in 10, skewing mostly to people who had more to lose.
If you were morbidly obese your probability of achieving a healthy weight is 1 in 1667 in a year.
And if you manage to thread that needle your average weight regain over 5 years is 80%.
https://jamanetwork.com/journals/jamanetworkopen/fullarticle...
A quick explanation about what Ozempic is would be helpful in this case. Not every country uses the same name for their drugs and the brand names are often very different
That's an interesting remark, considering this is most famous drug on the face of the Earth, and only has one brand name worldwide (in a different dosage it's called Wegovy, and when it's released as a pill it will be called Rybelsus). Its generic name is Semaglutide.
And if that's true, what is the conclusion? Stay obese to have a beautiful skin (and deal with the associated health effects)?
A quick explanation about what Ozempic is would be helpful in this case. Not every country uses the same name for their drugs and the brand names are often very different
It's strange how there is almost never a shortcut to anything. Like a universal law. So now you might get free weight loss without making any effort at all, but you'll also look older in the process? I have to say, my father has been taking it, and I noticed that he does look older all of a sudden...and his weight loss also plateaued. I thought it was just my imagination, but maybe not.
IMO GLP-1 agonists are obviously not free, from first principles. They might be for diabetics who carefully manage their diet, but many (most?) people using them for weight loss usually already have shitty diets with poor macronutrient balance and micronutrient deficiencies. Eating less of the crappy food they were eating before just makes the true situation worse. This is just the latest [1][2] evidence for the obvi…
In my experience, it turned down the reward feedback for calorie dense food, and I would usually now prefer something like a lentil daal over a Dominos.
Nothing worse than losing weight but most of the weight loss was muscle mass.
Earlier quoted context omitted.
That's an interesting remark, considering this is most famous drug on the face of the Earth, and only has one brand name worldwide (in a different dosage it's called Wegovy, and when it's released as a pill it will be called Rybelsus). Its generic name is Semaglutide.
Wouldn’t the most famous drug be: aspirin, heroin, cocaine, paracetamol, or maybe viagra? I don’t know from your comment what it is, and it was unhelpful. Not really in the HN spirit. For future readers, it seems to be an anti-diabetic drug or artificial hormone originating in the 70s. More educated comments than mine are very welcome.
Earlier quoted context omitted.
The problem is she swallowed everything else too. The obesity is a massive problem that needs to be remedied and yes there may be side effects along the way but literally nothing else works for obesity except roux-en-Y gastric bypass. Palid skin is nothing compared to losing your foot to diabetes.
I know someone who lost an eye to diabetes, so your comment is certainly not hyperbole.