Live data from Hacker News

Tripping on Xenon Gas (2023)

tripsitter.substack.com

71–80 of 202 posts

Re: Tripping on Xenon Gas (2023)

#72
These days we have some theory about this. See Stuart Hameroff MD, a Professor of Anesthesiology and Psychology, and Director of the Center for Consciousness Studies at the University of Arizona.

To sum it up from my limited understanding: This disturbs the quantum coherance in the microtubelies in all cells (But mostly nurons) which is needed for consciousness to "limit" itself to a identity.

Re: Tripping on Xenon Gas (2023)

#74

These days we have some theory about this. See Stuart Hameroff MD, a Professor of Anesthesiology and Psychology, and Director of the Center for Consciousness Studies at the University of Arizona. To sum it up from my limited understanding: This disturbs the quantum coherance in the microtubelies in all cells (But mostly nurons) which is needed for consciousness to "limit" itself to a identity.

Ummmm what?

Re: Tripping on Xenon Gas (2023)

#76

It's fascinating to me that a pure element would have such immediate and significant effects on the human mind. I would think that this would generally require a more complex molecular shape that can fit with various receptors in the body and trigger the release of dopamine and other neurotransmitters. Apparently, Xenon does this by acting as an antagonist of the N-methyl-D-aspartate (NMDA) receptor, a subtype of glu…

My understanding of mechanisms from a chemistry perspective is that the anesthetics mess with the phospholipid bilayer making up the cell membrane in a way that closes off receptors. So it makes intuitive sense that dissolving giant xenon molecules in a layer could mess with it from a pure physical perspective. What's weird, to my mind, is that other noble gases don't have any effect - you'd expect a gradient.

Re: Tripping on Xenon Gas (2023)

#77

These days we have some theory about this. See Stuart Hameroff MD, a Professor of Anesthesiology and Psychology, and Director of the Center for Consciousness Studies at the University of Arizona. To sum it up from my limited understanding: This disturbs the quantum coherance in the microtubelies in all cells (But mostly nurons) which is needed for consciousness to "limit" itself to a identity.

Ummmm what?

There are so many talks, I just picked a shorter one: https://www.youtube.com/watch?v=DZ484WZS-lo

Re: Tripping on Xenon Gas (2023)

#78
post #41

Earlier quoted context omitted.

I wouldn’t call nitrous oxide “psychedelic” although it is certainly psychoactive.

It depends on your definition of psychedelic then, as I find different sources supporting either argument, but NO2 produces powerful hallucinations, euphoria, dissociation, and sometimes creativity much like typical psychedelics, but on a compressed timescale.

Hallucinations on N2O? How long do you have to breath it for that?

Re: Tripping on Xenon Gas (2023)

#79

> Argon [...] cost about $2 per liter each. Uh, what?? No it doesn't. I'm a hobbyist welder. When TIG welding you typically use 100% argon gas. I have a 60 cu ft cylinder hooked up to my welder right now; it costs $89 to refill at my local Airgas store. That's approximately 5.2 cents per liter. Here's a 40 cu ft tank of argon for sale on Amazon for $205: https://www.amazon.com/100-Argon-Welding-Tank-CGA/dp/B00I4Z6...…

I guess "medical-grade" xenon (for anesthesia) would be extremely more expensive (with warranties on purity from contaminants such as pump grease).

Re: Tripping on Xenon Gas (2023)

#80

In college I used a lot of nitrous. I got small cartridges and a “cracker” with a balloon. It was pretty euphoric. I stopped after recording myself taking it. I was unconscious a lot longer than I remembered being, and even though I was probably never at risk of suffocating there were long periods where I didn’t see myself breathing. That was enough. I regret the effects it may have had on my brain. It’s impossible t…

Unconscious from the hypoxia?

Why don’t recreational nitrous users mix in some oxygen like medical users do?

Post reply on HN