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Brain waves appear to wash out waste during sleep in mice

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Re: Brain waves appear to wash out waste during sleep in mice

#71

Post by JPLeRouzic »

achow wrote: post #3

More details at Washington Univ' site: https://medicine.wustl.edu/news/neurons-help-flush-waste-out... Could not find any free access to the paper, even though the Univ' says "This work was supported by the National Institutes of Health (NIH); the BJC Investigators Program at Washington University; and the Neuroscience Innovation Foundation." These kind of grant funded research should be accessible at the least from…

More discussion about this paper on ALZ forum:

https://www.alzforum.org/news/research-news/do-sleep-rhythms...

Re: Brain waves appear to wash out waste during sleep in mice

#72

Post by ineedaj0b »

smolder wrote: post #69
bloqs wrote: post #46

Earlier quoted context omitted.

Modafinil does exactly this.

Huh? It cleans the brain? Care to elaborate or provide a source?

It certainly keeps you alert. Removes the ‘sleepy/tired’ feeling. But it might not clean the brain.

It might change the comfort level of ‘clean’ you brain finds acceptable before commanding the janitor out of his closet.

Re: Brain waves appear to wash out waste during sleep in mice

#73

Post by DonHopkins »

zadler wrote: post #52
_y5hn wrote: post #35

Earlier quoted context omitted.

That's been in use for thousands of years already: yoga, pranayama and meditation. There are courses one can take where one learns this, like Art of Living and any other that follows the same traditions. Yes, there's research on that, and new studies should absolutely gain from this study. Not entirely sure you'll observe the same effect, that depends on meditator, but you can fall asleep during practice. I have over…

Which exercises would you say trigger movement of cerebrospinal dluid in the brain?

https://www.youtube.com/watch?v=PM5_dgKDsrc

Re: Brain waves appear to wash out waste during sleep in mice

#74

Post by rpozarickij »

russellbeattie wrote: post #9

So, if we could induce those brain waves we wouldn't need sleep? Maybe in the future our AirPods will have a "rejuvenate" feature which plays tones that cause sleep like brain waves to go through and clean out our neurons. Probably not... I think our brains are like LLMs. We train them on sensory input we perceive over time, building up a data model that is unique to us. The models may generate similar results, but e…

I'd think that the brain isn't the only part of the human body that needs sleep/rest. Becoming immobile for such a long amount of time must have a much larger systemic purpose given that this is how our bodies evolved.

Re: Brain waves appear to wash out waste during sleep in mice

#75

Post by jimberlage »

baubino wrote: post #47
gapan wrote: post #37

Earlier quoted context omitted.

I think the point was that every member of the public should have access to publicly funded research at least through the university's website, rather than at least everyone currently in universities should have access.

I agree but I also know (as a university employee) that the reason they don’t do this is because then they would have to pay for and manage the hosting of hundreds of thousands of articles. From the university’s perspective, managing and hosting articles is exactly what publishers do, so universities cede that work to publishers. What is needed is a public database of all publicly-funded research.

At first I was like, “oh, that’s a reasonable perspective,” and then I thought about it more and it kinda isn’t?

When I buy a keyboard, the manufacturer doesn’t run a shipping company, so they use $x from the purchase price to subcontract shipping. (They tell me it’s separate at billing, but they don’t make me ring up DSL myself either.)

When I hire an electrician, they buy materials from Home Depot, so they use $x from the purchase price for materials. (They sometimes break down the bill into materials and labor, but they don’t make me drive to Home Depot myself and buy every part.)

When the public hires academics to do research, they have administrative overhead and have to hire a publisher, so they use $x from the grant for administrative overhead and…

Abdicate responsibility for the $y needed for publishing and pretend the public didn’t intend for part of the grant money to go to that??

Re: Brain waves appear to wash out waste during sleep in mice

#76

Post by cj »

bayindirh wrote: post #63
SturgeonsLaw wrote: post #42

Earlier quoted context omitted.

If you email the authors they might be happy to send you a copy - scientists tend to be in favour of the free exchange of information, there's no restriction on them sharing their paper if they choose to, and they don't get royalties from journal subscriptions so they have no vested interest in paywalling their research

Not all of them. I sent a couple of such mails, to only get back the freely available summary PDFs back. Even with the same checksum with the ones on the web.

Yep. My dog was part of a study at UC Davis. All I was able to get was an abstract.

Re: Brain waves appear to wash out waste during sleep in mice

#78

Post by drowsspa »

ineedaj0b wrote: post #21

We need to figure out what activity or thought creates waves most similar to the cleaning function. Maybe it’s dreaming? Dreaming by my experience is tedious and not restful… I have 4-6 dreams every night and never feel like I’m truly asleep. Shouldn’t be hard to figure out with an EKG and a decent graph to see what your aiming for.

I almost never remember my dreams. When I do, it means I had a really bad night's sleep and I don't feel rested.

4 to 6 dreams every night sounds exhausting. You should probably check it out with a doctor, it seems you're subconsciously waking up too often during the night.

Re: Brain waves appear to wash out waste during sleep in mice

#80

Post by dotnet00 »

ArthurAardvark wrote: post #55
_y5hn wrote: post #35

Earlier quoted context omitted.

That's been in use for thousands of years already: yoga, pranayama and meditation. There are courses one can take where one learns this, like Art of Living and any other that follows the same traditions. Yes, there's research on that, and new studies should absolutely gain from this study. Not entirely sure you'll observe the same effect, that depends on meditator, but you can fall asleep during practice. I have over…

It's hilarious to me that these practices are laughed off, trivialized through memes and hyper-objectivity (science can't evaluate their value in a practical manner -> "Lulz hippie-dippie nonsense for ditzy/ungrounded women!!!!" -- Western dolt). Its insane considering their benefits...that are of course tragically perfect for those who would never participate Of course that's a huge generality, I'd say it may be 1 o…

I've seen actual psychiatrists suggesting meditation or yoga as additional ways to help with certain issues (eg anxiety) along with medicine, and the benefits of say, just conscious, controlled breathing as is involved in both are obvious to anyone who has a temper.

I wouldn't be surprised if the idea that it's completely useless because it can't be scientifically observed in a traditional sense is highly correlated with people who think that mental health issues aren't real in general.

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