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Taking low-dose aspirin is associated with 20% reduction in cancer deaths

cardiff.ac.uk

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Re: Taking low-dose aspirin is associated with 20% reduction in cancer deaths

#73
post #69

This is a meta analysis of observational studies. There's random controlled trial which showed all cause mortality was 14% higher for "healthy older adults who received daily aspirin than among those who received placebo" https://www.nejm.org/doi/full/10.1056/nejmoa1803955

The meta analysis is studying asprin as a cancer treatment, so the subjects were patients who already had cancer, not healthy adults taking it as a preventative. Daily asprin could both be bad for healthy adults and good for cancer patients.

Re: Taking low-dose aspirin is associated with 20% reduction in cancer deaths

#74
post #41

This has to be balanced against this news: "Daily low dose aspirin increases brain bleeding risk by 38% in older adults." See: https://www.medicalnewstoday.com/articles/low-dose-aspirin-r...

Which is worse?

Note that the patients in the meta-analysis already had cancer.

Re: Taking low-dose aspirin is associated with 20% reduction in cancer deaths

#76

This has to be balanced against this news: "Daily low dose aspirin increases brain bleeding risk by 38% in older adults." See: https://www.medicalnewstoday.com/articles/low-dose-aspirin-r...

Brain bleeding is very rare. That 38% number is a *relative risk ratio*. I'm always wary of studies that use such ratios to make an effect seem large. The following excerpts from the article you cited state: For the study, the researchers analyzed data from 19,114 adults with an average age of 74 years old. Altogether, 1.1% of those taking aspirin (108 individuals) experienced intracranial bleeding, while the same wa…

It always amazes me how you can take numbers and twist them they way they fit you and be technically correct. I bet many (if not most) people will only remember the headline.

Re: Taking low-dose aspirin is associated with 20% reduction in cancer deaths

#78

Earlier quoted context omitted.

Brain bleeding is very rare. That 38% number is a *relative risk ratio*. I'm always wary of studies that use such ratios to make an effect seem large. The following excerpts from the article you cited state: For the study, the researchers analyzed data from 19,114 adults with an average age of 74 years old. Altogether, 1.1% of those taking aspirin (108 individuals) experienced intracranial bleeding, while the same wa…

It always amazes me how you can take numbers and twist them they way they fit you and be technically correct. I bet many (if not most) people will only remember the headline.

Check out the famous book "How to Lie with Statistics"

Re: Taking low-dose aspirin is associated with 20% reduction in cancer deaths

#79

People who are diligent to keep taking an aspirin pill day in and day out even though they are not sick are likely sufficiently worried about their health to also subject themselves to timely cancer screening.

This is a study of cancer patients, not the general population.

Re: Taking low-dose aspirin is associated with 20% reduction in cancer deaths

#80
post #65

Earlier quoted context omitted.

what if I do all the other things that go along with drinking for health, like speak Italian or French while I drink?

First search hit: They report preventable deaths caused by alcohol is higher in France than anywhere else in Europe. Speaking French doesn't appear to help you. Maybe Italian is better.

Sounds like bs if you look at Russian numbers.
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