The Galactic Adventures DLC had an "adventure creator" where you could create simple scenarios with your other creations. I didn't realize it at the time, but this was my first exposure to programming. It really lit my imagination on fire and got me interested in game development, and is ultimately how I ended up as a programmer.
Such was my love for this game, I ended up getting involved in the Spore forum ("The Sporum", ha). Strangely enough, one of the official boards was "Creationism vs. Evolution", or CvE as it was known by the forum's denizens. I grew up in a deeply rural and fundamentalist area, so CvE was my first real exposure to the beliefs of the other side, rather than the strawmen the church presented. I argued sincerely on the side of Creationism and got handily defeated by facts and logic many times. It didn't fully change my mind at the time, but it planted the seeds of deprogramming.
So in a way, this game that was so disappointing for many has a lot of personal significance to me. It had a big influence on my personal beliefs and my career. Thanks I guess, Will Wright.