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Fentanyl vaccine tested in rats

uh.edu

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Re: Fentanyl vaccine tested in rats

#71

Earlier quoted context omitted.

The link you posted says that the original rat park researcher's own graduate student was unable to replicate the original experiment when he tried reducing the confounds. That seems like the most favorable possible situation for a replication to me. It also says that one confound was that morphine consumption wasn't measured in the same way between conditions in the original experiment. That seems pretty bad to me.…

Just saying, since neither humans nor rodents typically live in cages, maybe rodent experiments would be more predictive of human behavior if they weren't forced into living in small cages.

looks around his cubicle

I must be in the control group. ;)

Re: Fentanyl vaccine tested in rats

#73
post #40

Earlier quoted context omitted.

Would this be solved by legalizing and regulating opiates?

You would think. But FDA is going opposite direction making legal opiates even harder to get by putting pressure on doctors.

Yeah. The way I understand it is that most users would prefer natural opiates but they're getting more and more expensive while synthetics are cheaper than ever. And, because the market is unregulated, even if you try to buy heroin you'll end up getting fentanyl mixed in anyway.

Re: Fentanyl vaccine tested in rats

#74
post #53

Oh boy, the pharmaceutical companies can sell a new product to help solve the mess that one of their previous products created. An opioid that's more potent, more addictive, and more deadly than heroin should never have gone to market in the first place. It speaks of enormous corruption and a complete lack of ethics when regulators didn't see an issue with fentanyl and let it move forward. The "but people are in pain…

its not only that, the vaccine will create issues for people when they want to have a surgery so it CREATES NEW ISSUES

Re: Fentanyl vaccine tested in rats

#75
Does this prevent death or just the perceived effects of the drug? This could be very dangerous for users who relapse. There is a known pattern of users who get off opioids then relapse and die because their bodies can no longer tolerate the doses that they were used to taking before they quit. This could have a similar effect where users take the drug, don't feel it, and then increase their dose to lethal levels hoping that they can get high again or believing that the drugs they purchased are diluted or ineffective.

Re: Fentanyl vaccine tested in rats

#76
This is kind of strange. Is it really fentanyl-specific, or does it effect all opioids? Problems either way; if just fentanyl, then, duh, that's not the only way to get high. If all opioids... So it makes opioids no longer available for pain relief... forever? ("vaccine"?). (Major surgery and recovery without opioids is no walk in the park, it's PTSD-inducing excruciating pain).

It claims to block the ability to get high -- does it also block overdose potential? Or is this just going to lead to lots of people OD'ing as they try to take enough to get high?

One way or another, it seems likely to lead to even greater harm as addicted people look for something else that does work.

Honestly seems like a bad idea overall, based on wrong and unuseful ideas about the nature of addiction.

Re: Fentanyl vaccine tested in rats

#80
post #67
post #53

Oh boy, the pharmaceutical companies can sell a new product to help solve the mess that one of their previous products created. An opioid that's more potent, more addictive, and more deadly than heroin should never have gone to market in the first place. It speaks of enormous corruption and a complete lack of ethics when regulators didn't see an issue with fentanyl and let it move forward. The "but people are in pain…

>sell a new product to help solve the mess that one of their previous products created That's gotta describe like 75% of US healthcare budget, right? Red Dye #40, BPA, preservatives, emulsifiers, PFAS -> ADHD, Anxiety, Depression -> Adderall, Xanax, Prozac Sugar, seed oils, preservatives, endocrine-disrupting chemicals in food, water & air -> Obesity, hypertension, diabetes -> Lipitor, Insulin Alcohol, smoked/grilled…

I don’t think there’s a reputable link between red dye #40, BPA, preservatives, emulsifiers(?!) and ADHD, anxiety, and depression.

Further, are you claiming meat, tobacco, and alcohol are products of the US pharmaceutical industry?

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