I saw a Second City improve last winter, and one of the better sketches exploited Facebook similarly, albeit in a more lighthearted and humorous way.
Prior to the performance they would find an audience member's Facebook page using their credit card or mailing address (presumably), and write a sketch based on the details extracted from his or her page.
They incorporated the lucky patron's inevitable reaction into the sketch under the pretense of reprimanding him for disrupting the show. After letting him squirm a bit under the spotlight, the punchline was projecting his Facebook page on the screen across the stage.