Too much to read dude, should I get stoned now or not?
Cannabinoids Block Cellular Entry of SARS-CoV-2 and the Emerging Variants
71–80 of 139 posts
Re: Cannabinoids Block Cellular Entry of SARS-CoV-2 and the Emerging Variants
#72Totally anecdotal but my girlfriend and I recently went to wedding and even with pre testing and everyone vaccinated, a lot of people got Covid. I was super high that night (as most nights) and walked away unscathed. Obviously this could be due to a lot of things but that hasn’t stopped me from rubbing it in all my friends faces. It’s been of the few times in my life where my weed habit looks smart, and I’m loving ev…
I've noticed a correlation between heavy herb smokers and not getting the virus or having mild symptoms. People that primarily do hash haven't had the same benefit, which is kind of weird. This is all anecdotal.
It makes sense that it would reduce symptoms since cannabis is a systemic immunosuppressant, whereas COVID generates runaway inflammation.
https://onlinelibrary.wiley.com/doi/full/10.1002/eji.2010406...
Re: Cannabinoids Block Cellular Entry of SARS-CoV-2 and the Emerging Variants
#73Earlier quoted context omitted.
That was the answer. People vocally cynical about the vaccines have always been using a strawman argument, in case you need a refresher a strawman argument requires two things: 1) creating a standard that was never used by the proponents 2) criticizing the made up standard to discredit the proponents on a medical level, it is clear this wasn't to stop the spread, it was to slow the spread as vaccinated infected have…
> That was the answer. People vocally cynical about the vaccines have always been using a strawman argument. No, we were repeatedly told that vaccines prevent both transmission and infection, and anyone trying to cynically rewrite history now is using a strawman argument. The whole point of the OSHA vaccine mandate was to prevent spread . If it was just a matter of how severe the disease is to you, then there is no r…
> the widespread use of those vaccines is the best way to keep COVID-19 from spreading within workplaces
[at a greater viral load than without the vaccines because all documents from Pzifer, Moderna, J&J, AstraZenaca, SinoPharm, and the people analyzing those documents made the same conclusion]
Re: Cannabinoids Block Cellular Entry of SARS-CoV-2 and the Emerging Variants
#74Good idea. Right-wing lunatics, QAnaon believers, anti-vax crusaders should get high and fcking relax already.
Re: Cannabinoids Block Cellular Entry of SARS-CoV-2 and the Emerging Variants
#75Too many "promising" studies like cannabis, vitamin D, chloroquine, ivermectin, etc have been later fact-checked by the CDC as bad science, to rely on anything but the CDC's word (or Fauci). Until the CDC says so I won't believe it. Right now it seems like mass vaccination is our only way out of this pandemic and back to normal.
Since the vaccinations are stopping the spread?
The intramuscular vaccinations currently available were never going to stop the spread and anyone familiar with animal studies of similar approaches to CoV vaccination knew that. Stating bold claims unsupported by balance of evidence and knowledge of mechanisms was a deliberate choice of messaging in hope of increasing campaign uptake.
They're helpful for preventing severe disease and death, for now -- this effect seems to be significantly offset by reduction in risk avoidance behaviours and government support for said behaviours.
The first gen vaccines do appear help somewhat with reducing infectivity period somewhat.. but once again this benefit is diluted when people are told to burn their source control (masks) and get back to the office.
We need better vaccines deliverable to mucosal membranes for infectious aerosol entry point protection and released under open source licensing. We also need better early treatments with sound scientific basis, and better post-acute-'recovery' sequelae treatments developed with the basis of a growing understanding of endothelial and immune pathology downstream of SARS2 infection.
Second from last but not least, we need efficacious airborne transmission interrupting non-pharmaceutical interventions that don't rely solely on individual behaviour. Finally, it would be nice to have fewer grifters and influencers blocking sound action while spreading nonsense.
Re: Cannabinoids Block Cellular Entry of SARS-CoV-2 and the Emerging Variants
#76Earlier quoted context omitted.
Well it is a single scientific study. To believe it as fact would be a fundamental misunderstanding of how science works. I agree with the spirit of your comment in that I would hold out for more scientific replication of these results to increase my confidence beyond the level of simple curiosity.
Has there been any such replication of the "natural immunity protection is equal or greater to vaccine protection" study(s) yet?
As a lay-person and not an epidemiologist, what logic is there for the idea that mRNA treatments that synthesize a single protein could be better than an actual infection which produces hundreds of those proteins per replication along with dozens or more proteins that may be used by the immune system to identify the virus?
Traditional vaccines at least dump most of the target viral proteins into the body.
Focusing on a single protein that may mutate in the target virus has always seemed myopic to me, let alone the assumption that this approach could possibly be more effective than an immune response to the actual virus. I’m not saying that this approach couldn’t work, just that it would, by definition, trigger a subset of the immune response of a whole virus vaccine.
Edit to add: by better, I mean better at triggering an immune response. I’m not arguing against the idea that a targeted, single protein approach is or is not better at reducing illness or death and therefore shouldn’t be pursued, just about the idea that recovered individuals would be less protected than a vaccinated individual on average.
Re: Cannabinoids Block Cellular Entry of SARS-CoV-2 and the Emerging Variants
#77Earlier quoted context omitted.
> That was the answer. People vocally cynical about the vaccines have always been using a strawman argument. No, we were repeatedly told that vaccines prevent both transmission and infection, and anyone trying to cynically rewrite history now is using a strawman argument. The whole point of the OSHA vaccine mandate was to prevent spread . If it was just a matter of how severe the disease is to you, then there is no r…
> the widespread use of those vaccines is the best way to keep COVID-19 from spreading within workplaces [at a greater viral load than without the vaccines because all documents from Pzifer, Moderna, J&J, AstraZenaca, SinoPharm, and the people analyzing those documents made the same conclusion]
Except they didn't make that point at all, because it's not relevant to a mandate. Please don't try to rewrite the quotes I am citing to make them support your point as that is literally trying to rewrite history. We have a word for that, and it's "gaslighting".
Re: Cannabinoids Block Cellular Entry of SARS-CoV-2 and the Emerging Variants
#78Earlier quoted context omitted.
> the widespread use of those vaccines is the best way to keep COVID-19 from spreading within workplaces [at a greater viral load than without the vaccines because all documents from Pzifer, Moderna, J&J, AstraZenaca, SinoPharm, and the people analyzing those documents made the same conclusion]
Except they didn't make that point at all, because it's not relevant to a mandate. Please don't try to rewrite the quotes I am citing to make them support your point as that is literally trying to rewrite history. We have a word for that, and it's "gaslighting".
the reason we are talking past each other is because you chose the wrong influencers, sorry thats been your experience. you should be dismayed at public facing communication for the broad audience, since the one time we needed them they messed that up.
> on a medical level, it is clear this wasn't to stop the spread, it was to slow the spread as vaccinated infected have smaller viral load for shorter time period compared to unvaccinated infected, as well as reduce severity and deaths of those that contained a viral load.
this was my goal post, it has not moved.
Re: Cannabinoids Block Cellular Entry of SARS-CoV-2 and the Emerging Variants
#79Totally anecdotal but my girlfriend and I recently went to wedding and even with pre testing and everyone vaccinated, a lot of people got Covid. I was super high that night (as most nights) and walked away unscathed. Obviously this could be due to a lot of things but that hasn’t stopped me from rubbing it in all my friends faces. It’s been of the few times in my life where my weed habit looks smart, and I’m loving ev…
Ditto. I'm a heavy(ish) user and I've never tested positive, despite being exposed more than once. Though admittedly I'm very cautious (always wear an N95, et al) and vaccinated.
Re: Cannabinoids Block Cellular Entry of SARS-CoV-2 and the Emerging Variants
#80Surprisingly high number of happily married stoners in here.