Live data from Hacker News

Blood sugar level follows perceived time rather than actual time in diabetics

pnas.org

71–80 of 90 posts

Re: Blood sugar level follows perceived time rather than actual time in diabetics

#71
post #8

Paper is from 2016. Huberman Labs has a great roundup (Nov '21) of the research on time perception - and several other related series on dopamine. The title of OP was not surprising after listening. https://hubermanlab.com/time-perception-and-entrainment-by-d...

I thought of this when reading the heading. I remember hearing ages ago that artificial sweeteners can kick someone out of ketosis sometimes and this podcast gave a good explanation of it.

Re: Blood sugar level follows perceived time rather than actual time in diabetics

#72
post #44

Earlier quoted context omitted.

I looked it up and can’t find anything that claims what you do that a pepper can blind you. I did find one article that said it can not after one exposure but possibly long term exposure could it just wasn’t tested. Do you have any sources on that claim? Thank you. I ask because we used to prank with peppers when I was young never worried about blinding someone though it was good if they rubbed their eyes or took a p…

Pepper spray also uses capsaicin, and in much higher concentrations than even the hottest peppers. If that's considered safe enough to be used by police and the general public then I'm pretty sure peppers are fine.

>If that's considered safe enough to be used by police

I mean, there has been some discussion over the last few years that police don't actually have as good a safety record as one might hope when doing things that could involve pepper spraying, or hitting, or tazing, or otherwise subduing people.

Re: Blood sugar level follows perceived time rather than actual time in diabetics

#73
I think people like to think of the brain/mind as a black hole/sink of the bodily processes and organs, but it has profound influence over them. Most obviously, there is fight or flight. But it's more subtle than that. The brain can influence inflammation in other parts of the body, which I can't back up right now, since it's just something I read in a science magazine a few years ago. Although here's something related about how the vagus nerve interacts with inflammation and metabolism:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082307/

Emotionally relevent hormones, the most obvious of which is cortisol, influence all kinds of bodily processes like hunger, metabolism, energy, etc. And one interesting one I can think of in my own life is bladder activity - ever notice how, if you're on a long trip, you can hold in your pee without even thinking about it, but as soon as you get home and head towards the bathroom, it's like your bladder is about to explode? Or how you can still get up and pee even if it doesn't feel like you need to?

And I think many of us have probably had the experience where we got so wrapped up in an interesting and challenging task that we forgot to become hungry, and maybe even missed our opportunity to be hungry until the next day.

Re: Blood sugar level follows perceived time rather than actual time in diabetics

#74
post #9

Suggestion works on taste buds too. In the nineties I had a thing for salsa and ate it most days at the office over things I steamed in the microwave. But I ate the mild salsas and couldn't tolerate the hot stuff. Still can't. So my boss decides to spice it up a bit, and mixes in some hot salsa. I didn't notice. Each day he gradually added more until it was all the hot stuff. I didn't notice. He went out and bought h…

that sounds like a really messed up thing for you boss to do to you

Re: Blood sugar level follows perceived time rather than actual time in diabetics

#75
post #68
post #30

Earlier quoted context omitted.

Good question, one that I don't know the answer to. But I know an experiment that can help us find out! Spicy-hot is a complex phenomenon, but it is my understanding that a large part of it is that the capsaicinoids react with the heat receptors in your mouth to adjust their baseline temperature; making them react to normal temperatures inside your mouth as if they were physically burning hot. If tolerance is a purel…

I eat very spicy food and I've noticed for a while now I've lost the ability to detect when I'm being burned in my mouth (at all, it's actually a bit of an issue sometimes). The rest of my body is the same as it always was - save for my fingers, which I can use to flip things in hot oil (probably a result of exposure to hot oil). Perhaps you are on to something :)

Chef hands come from calluses and the nerves in your fingers dying a little, I think! It's pretty useful tbh

Re: Blood sugar level follows perceived time rather than actual time in diabetics

#76

Earlier quoted context omitted.

Pepper spray also uses capsaicin, and in much higher concentrations than even the hottest peppers. If that's considered safe enough to be used by police and the general public then I'm pretty sure peppers are fine.

>If that's considered safe enough to be used by police I mean, there has been some discussion over the last few years that police don't actually have as good a safety record as one might hope when doing things that could involve pepper spraying, or hitting, or tazing, or otherwise subduing people.

It's not only used by police, but also by members of the public.

Re: Blood sugar level follows perceived time rather than actual time in diabetics

#77
post #49
post #31

Earlier quoted context omitted.

Yup! There’s a neurotransmitter for registering the compounds that trigger that hot sensation, and that neurotransmitter gets depleted over time, based on exposure. I don’t know the exact timeframes, but it’s on the order of days/weeks. https://en.m.wikipedia.org/wiki/Substance_P

Is it something similar for temperature? In my country some people go swimming all year around - even when the lake is covered in ice (they cut a hole). They say if you go everyday from summer to winter, you don't notice the temperature change and it's not such a big deal.

I’m not aware of anything like Substance P for temperature sensation. If I had to guess, it sounds more physiological— circulatory system adaption to handle colds exposures (e.g. blood vessel diameter). Maybe someone else here knows more and we can both learn!

Re: Blood sugar level follows perceived time rather than actual time in diabetics

#78
post #11

Earlier quoted context omitted.

Your story "proves" all the studies with sommeliers where they duped them into rating white wines (with red food coloring) as fancy red wines. All the sommeliers failed the blind tests. In fact all those studies showed was that the taste of wine stemmed primarily from the perception of the bottle rather than the actual taste.

Why should red and white wines taste so distinguishably different anyway? Because one is red colored and one is white? So what? Seems like your contempt here falls prey to the same biases as the sommeliers. Of course, you're not supposed to be an expert. But still, seems like a hypocritical thing to make fun of someone else for.

>Because one is red colored and one is white? So what?

So what depends on why things are different colors. For instance, red velvet cake is just vanilla cake dyed red with food coloring. In that case, there wouldn’t be a difference in taste. On the other end, vanilla bean ice cream has black specks distributed throughout from the contents of the vanilla bean itself. If you substituted black pepper, it might look the same but it would not taste the same. As Niksko explained, red and white wine are different due to differences in ingredients and different processes which impart different flavor and color.

Re: Blood sugar level follows perceived time rather than actual time in diabetics

#79
post #69

It gets much crazier. Here's a study in Nature showing "Glucose metabolism responds to perceived sugar intake more than actual sugar intake": https://www.nature.com/articles/s41598-020-72501-w?mc_cid=2b...

The idea is a bit too revolutionary to be fully understood by current generation. It breaks hadware/software model of living organisms. The implications might be so huge, no one today can imagine them.

We really need to teach those things in school now, so that our children do not reject them reflexively as voodoo and unscientific.

Re: Blood sugar level follows perceived time rather than actual time in diabetics

#80
post #9

Suggestion works on taste buds too. In the nineties I had a thing for salsa and ate it most days at the office over things I steamed in the microwave. But I ate the mild salsas and couldn't tolerate the hot stuff. Still can't. So my boss decides to spice it up a bit, and mixes in some hot salsa. I didn't notice. Each day he gradually added more until it was all the hot stuff. I didn't notice. He went out and bought h…

A farmer carried a baby bull calf across his field every day. As each day passed, the calf grew a little more and became slightly heavier. Just a little bit more weight each day.

By the time the calf had become a bull, the farmer was so strong he could carry a bull the length of his field while talking on his cell phone.

Or so they say...

Post reply on HN