I'm a life-long Portlander, and absolutely love the place. I'm glad that you and your wife have been having a good time thus far- it can indeed be a great place to live and work. It sounds like you guys have been getting to experience a lot of my favorite things about the region, which is great to hear- many newcomers don't get out as much as you guys are. That said, however, Pakourama raises some valid points, and I think it's incorrect to dismiss them out of hand.
Portland does indeed have an extremely high homeless population, and there are real structural issue with how the city deals with that problem. Depending on where and how you live, it's possible to ignore that problem, or to not fully appreciate how bad it is, but believe me: it's real. It's also gotten a lot worse in recent years due to the economy as well as the wars in Iraq and Afghanistan. Our local VAs have brought on extra social workers to try and deal specifically with homeless vets, and the various homeless services agencies have been expanding, as well.
We also have inflated unemployment, mostly because the city's such a nice place to live that lots of people move here without a job, or, when they lose their job, don't leave. If you've got technical skills, it's a great time and place to find a job- but if you don't, there are way fewer options than it might seem, and it is can be an extremely competitive job scene. It's like that everywhere, I know, but for whatever reason it's especially bad in Portland. I am (honestly, no sarcasm) thrilled for your wife that she had such an easy time finding a job; not knowing anything about her, I can say that if she's not a techie than hers is the first such story I've heard from a new arrival in Portland over the last few years. Far, far, far more common is the "well, I picked up a few hours here, and a few hours there, but I can't find anything full-time, and I've been looking for six months, etc. etc."
Regarding the weather- winters in Portland affect everybody differently. SAD is indeed endemic; my GP blames it on wide-spread vitamin D deficiency, but who knows. At least in the 1990s, Portland did have an above-normal level of teen suicide. I don't think the rain here is any worse than Seattle, and from what I've heard the SAD issue is about the same up there as it is down here. But it's a real thing... you'll know what I'm talking about when we get a freak-occurrence sunny day in Feburary (typically, it will have been raining or at least completely overcast for three or four months by that point) and suddenly everybody around you seems ten times happier.
Anyway, welcome to Portland, and like I said, I'm glad you're enjoying it. I love it, myself, and feel like the positives vastly outweigh the negatives. But it's important to have a complete and balanced view of one's city, and Portland definitely has room for improvement.