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Brain imaging before and after Covid-19 in UK Biobank

medrxiv.org

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Re: Brain imaging before and after Covid-19 in UK Biobank

#71

Post by dukeofdoom »

b0sk wrote: post #68
dukeofdoom wrote: post #52

Earlier quoted context omitted.

As someone not getting the vaccine. I'll explain my reasoning. At this point, the odds of getting COVID are small. And much better treatments are around the corner. Thus a 1% mortality rate for the elderly, with multiple co-morbidities, will be even lower for someone my age should I get it at some point. Vaccines introduce a foreign substance 100% of the time into your body, sometimes have side effects. I won't even…

> At this point, the odds of getting COVID are small. That's because the herd around you has been vaccinated. So you are OK with others getting vaccinated for your benefit but wouldn't do your part to benefit the herd. Awesome! Maybe your post is parody. Can't really tell.

I never asked the herd to do anything, thus I am not in any way obliged to them morally. They did it for their own protection. I was willing to accept the 1% of dying, even if no one was vaccinated.

Re: Brain imaging before and after Covid-19 in UK Biobank

#72

Post by Majromax »

ekianjo wrote: post #43
JohnJamesRambo wrote: post #4

I wish I could get people that are avoiding the COVID vaccine “because we don’t know what the long term effects are” to realize that we have real data showing that there are long term effects from getting full blown COVID. You don’t want a tiny piece of mRNA but you want the whole organism reproducing in your body? The whole genome and all the proteins made?

> You don’t want a tiny piece of mRNA but you want the whole organism reproducing in your body? Rather than injecting yourself with mRNA which will create long-term antibodies in your organism which will be reactivated any time something like COVID19 appears again in the nature, it's probably safer to rely on COVID19 treatments are are short lived (as in, metabolized) and reduce the viral load swiftly.

> Rather than injecting yourself with mRNA which will create long-term antibodies in your organism which will be reactivated any time something like COVID19 appears again in the nature,

That's... supposed to be bad?

Re: Brain imaging before and after Covid-19 in UK Biobank

#73

Post by megous »

anthomtb wrote: post #15
hallway_monitor wrote: post #6

Earlier quoted context omitted.

Agree completely. That said, ideally I don't want either. Since a lot of people wanted to get vaccinated immediately, I can avoid that and the virus with very high probability. If needed, I'll take v3 or so of the mRNA vaccine.

Most of the arguments against accepting an mRNA shot read as “too new, do not want” to me. What are the specific long-term side effects that one should be aware of when accepting an mRNA shot?

This + side-effects not going away as advertised. Finding some longer term side effect studies is not that easy in general search engine, due to slew of regurgitated basic information about side effects.

Would be nice to have some data, instead of a ton of articles that say the same old "most symptoms go away within a few days". How does one decide whether to vaccinate or not based on such information? What is most? What is few days?

Some side effects are extremely common, like shoulder pain. Acceptable if it goes away in a week, let's say. But if there's a risk I'll have it for 3 months or forever, I'd like to know how common is that to make a calculated risk assessment. 2-3% probably not.

And this will only be more apparent with time and more studies. The study I managed to find tracked people only for 8 days, had a nice graph of symptoms fading away with time. Mind calming exponential decay. :) Good, but 5% still had some symptoms at day 8. How many do have them at day 60?

I don't understand why such information has to be so hard to find for normal people, who don't spend days searching around on google scholar.

Re: Brain imaging before and after Covid-19 in UK Biobank

#74

Post by MAGZine »

dukeofdoom wrote: post #64
dntrkv wrote: post #59

Earlier quoted context omitted.

> Vaccines introduce a foreign substance 100% of the time into your body So does the virus. And all of our data shows the virus is much, much worse.

yes, but by taking the vaccine 100% chance of doing that. Virus, only if I get it.

You're weighing a real possibility against an unfounded one.

P(Complications|Covid) has a calculatable probability.

P(Complications|Vaccine) is not, because we don't even know if they exist. And further, we strongly suspect they don't.

In other words, I think you're trading one hand for (at best) one in the bush.

Re: Brain imaging before and after Covid-19 in UK Biobank

#75

Post by pepperberg »

TaupeRanger wrote: post #54
ganzuul wrote: post #41

Earlier quoted context omitted.

Call me stupid for waiting to get vaccinated... But I'm not stupid enough to base that decision on a Twitter thread. The problem I have is that inclusive discussion is being suppressed, and I can't make a decision based on clearly biased information. ref. https://www.youtube.com/watch?v=-_NNTVJzqtY

The video you linked is removed.for violating guidelines, which I'm guessing means it had a conspiratorial slant. Discussion does not have to include unsupported or crackpot claims to be "inclusive".

Instead of looking up the original video (e.g. by using the watch id), you immediately write it off as "crackpot claims" because some unknown authority at YouTube removed it, citing broad community guidelines.

Maybe we should stick to your words from 4 days ago:

"Science reporting is terrible and the general education system doesn't teach rational skepticism, it teaches unconditional trust of intellectual authority."

Is this really a skeptical, discussion-friendly behaviour or an unconditional trust in some kind of authority?

Re: Brain imaging before and after Covid-19 in UK Biobank

#76

Post by gspr »

dukeofdoom wrote: post #52
JohnJamesRambo wrote: post #4

I wish I could get people that are avoiding the COVID vaccine “because we don’t know what the long term effects are” to realize that we have real data showing that there are long term effects from getting full blown COVID. You don’t want a tiny piece of mRNA but you want the whole organism reproducing in your body? The whole genome and all the proteins made?

As someone not getting the vaccine. I'll explain my reasoning. At this point, the odds of getting COVID are small. And much better treatments are around the corner. Thus a 1% mortality rate for the elderly, with multiple co-morbidities, will be even lower for someone my age should I get it at some point. Vaccines introduce a foreign substance 100% of the time into your body, sometimes have side effects. I won't even…

Kindly go to hell (or go live alone in the woods somewhere), you egoistical bastard.

Re: Brain imaging before and after Covid-19 in UK Biobank

#77

Post by MAGZine »

ganzuul wrote: post #41
elboulangero wrote: post #18

FWIW this thread was a good read: https://mobile.twitter.com/skepticalzebra/status/14058997241... Apparently there are previous studies (pre-covid Era) that found similar changes in the brain associated with loss of smell. Quoting: > What if I told you there was also an illness in which: > "grey matter reduction was observed in the gyrus rectus, orbitofrontal cortex, thalamus, and the insula" > This is taken from a s…

Call me stupid for waiting to get vaccinated... But I'm not stupid enough to base that decision on a Twitter thread. The problem I have is that inclusive discussion is being suppressed, and I can't make a decision based on clearly biased information. ref. https://www.youtube.com/watch?v=-_NNTVJzqtY

You should not make your decisions based on social media AT ALL.

if you have questions, talk to a physician.

Re: Brain imaging before and after Covid-19 in UK Biobank

#78

Post by torben-friis »

causality0 wrote: post #28
JohnJamesRambo wrote: post #4

I wish I could get people that are avoiding the COVID vaccine “because we don’t know what the long term effects are” to realize that we have real data showing that there are long term effects from getting full blown COVID. You don’t want a tiny piece of mRNA but you want the whole organism reproducing in your body? The whole genome and all the proteins made?

Yeah. I had complete loss of smell and taste, which came back about 90% over the next six weeks. It was fine for a month and then it went wonky. Probably 30% of my "scent spectrum" has now been replaced with the same burnt meat smell/taste. Everything from chocolate to feces to hamburgers now has the same core odor. It really, really sucks.

Don't lose hope. I got in October, similar effects, and I've been recovering a lot of my smell and taste, veery slowly and in "bursts".

Nowadays I'm almost fully ok, the only smells I haven't recovered are body odor (which I can smell, it's just really different) and feces and trash, which for some reason smell in a very particular sweet way, kinda like rotten meat.

That last one, for some reason, seems to be really common, since several friends that also lost smell have had the same exact change.

Re: Brain imaging before and after Covid-19 in UK Biobank

#79

Post by codezero »

vajrabum wrote: post #55
ekianjo wrote: post #43

Earlier quoted context omitted.

> You don’t want a tiny piece of mRNA but you want the whole organism reproducing in your body? Rather than injecting yourself with mRNA which will create long-term antibodies in your organism which will be reactivated any time something like COVID19 appears again in the nature, it's probably safer to rely on COVID19 treatments are are short lived (as in, metabolized) and reduce the viral load swiftly.

What other viral diseases are easily treatable by medication as opposed to vaccination? Are there any?

I’m sure most people would prefer vaccines, but herpes is a commonly medicated virus lacking in vaccination availability.

Re: Brain imaging before and after Covid-19 in UK Biobank

#80

Post by dangom »

plank_time wrote: post #12
JohnJamesRambo wrote: post #4

I wish I could get people that are avoiding the COVID vaccine “because we don’t know what the long term effects are” to realize that we have real data showing that there are long term effects from getting full blown COVID. You don’t want a tiny piece of mRNA but you want the whole organism reproducing in your body? The whole genome and all the proteins made?

What is the percentage of people who suffered any long term brain effects? And did they do the same study against people who got the flu and other diseases?

They looked at longitudinal data from people before and after COVID. Most of these people had the flu before, none had COVID because it didn't exist in humans then. There is no way to run the exact same study (UK biobank) on people who got the flu.
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