BioNTech CEO applies Covid-19 vaccine's mRNA tech to multiple sclerosis • Hacker News Board

Re: BioNTech CEO applies Covid-19 vaccine's mRNA tech to multiple sclerosis

#71

Post by jfim » Wed, Jan 13, 2021, 6:46 AM UTC

Zhenya wrote: post #69

djbebs wrote: post #35

Earlier quoted context omitted.

Doubtful. Insurances dont run at a loss, every penny that goes into them they take a cut as profits. If the treatment is expensive, great! More demand for their product, and even if their cut is the same, their profit and revenue will be greater.

This doesn't make sense to me. Insurance in a collective risk pooling scheme. How do they take a cut when they are the ones paying out?

There's an 80/20 rule in the ACA [0] where at least 80 percent of the premiums paid must be spent on healthcare costs, otherwise the difference between 80 percent and the actual amount paid must be returned.

Sounds great, until the insurance companies figured out that the best way to make more profit with this profit cap is to pay out more and increase the premiums accordingly. [1] Obviously, the hospitals don't mind that either.

[0] https://www.healthcare.gov/health-care-law-protections/rate-...

[1] https://www.aeaweb.org/research/regulating-health-insurers-a...

Re: BioNTech CEO applies Covid-19 vaccine's mRNA tech to multiple sclerosis

#72

Post by shadowprofile77 » Wed, Jan 13, 2021, 8:24 AM UTC

alfl wrote: post #68

shadowprofile77 wrote: post #57

Earlier quoted context omitted.

>I believe that it's considerably worse than 1918. The COVID IFR is known to be lower than that of the 1918 influenza pandemic, which killed between 50 and 100 million people in less than a year, and pulled that off at a time when the Earth's population was a quarter of what it is today and much less mobile. I have no idea whatsoever where you get the idea that COVID is worse than 1918. It most emphatically (at least…

OP was talking about the “quality of death” being subjectively worse IMO.

If it was describing that as "worse", didn't leave it very clear, and in any case, that's an awfully ambiguous comparison. Death from influenza was slowly asphyxiating, and sometimes even hemorrhagic, neither of which sound especially peaceful.

Re: BioNTech CEO applies Covid-19 vaccine's mRNA tech to multiple sclerosis

#73

Post by yread » Wed, Jan 13, 2021, 8:31 AM UTC

usehackernews wrote: post #70

syntaxing wrote: post #36

I really hope this mRNA train keeps going and companies succeed executing on it. Does anyone know the status for CRISPR medical technology? I remembering hearing about all these great applications using CaaS-9 and 13 but I haven’t really heard any new medical breakthroughs recently (though the hemophilia “cure” was awesome!).

CRISPR is a great example of a technology that has not yet made a meaningful economic contribution. Although the technique for editing DNA was discovered in 2012—and a Nobel Prize was awarded to its two discoverers this year—no treatment using CRISPR has been approved outside of clinical trials. So far, its impact has been limited to making researchers more productive—not a bad thing, to be sure, but not close to CRI…

CRISPR most definitely made a huge economic contribution. It's used massively https://pubmed.ncbi.nlm.nih.gov/?term=crispr and it allows to do things that would have been very difficult (and expensive, thus providing value) to do otherwise, allowing researchers to do new therapies and diagnostic tools that WERE applied in clinic.

That's a bit like saying containers haven't provided meaningful economic contribution because consumers don't use them very often.

Re: BioNTech CEO applies Covid-19 vaccine's mRNA tech to multiple sclerosis

#74

Post by VEEG889 » Wed, Jan 13, 2021, 2:45 PM UTC

I was diagnosed with multiple sclerosis 1 month after I turned fifty. My grandma is ninety-six and had it since she was in her 20s. I have been on WORLDHERBSCLINIC MS HERBAL FORMULA, the first TWO MONTHS was daily and now I am on 3 times a week. It has made a tremendous difference for me. The fatigue never gets to me again. When I do too much, I don’t feel weak anymore..

Re: BioNTech CEO applies Covid-19 vaccine's mRNA tech to multiple sclerosis

#75

Post by usehackernews » Wed, Jan 13, 2021, 4:05 PM UTC

yread wrote: post #73

usehackernews wrote: post #70

Earlier quoted context omitted.

CRISPR is a great example of a technology that has not yet made a meaningful economic contribution. Although the technique for editing DNA was discovered in 2012—and a Nobel Prize was awarded to its two discoverers this year—no treatment using CRISPR has been approved outside of clinical trials. So far, its impact has been limited to making researchers more productive—not a bad thing, to be sure, but not close to CRI…

CRISPR most definitely made a huge economic contribution. It's used massively https://pubmed.ncbi.nlm.nih.gov/?term=crispr and it allows to do things that would have been very difficult (and expensive, thus providing value) to do otherwise, allowing researchers to do new therapies and diagnostic tools that WERE applied in clinic. That's a bit like saying containers haven't provided meaningful economic contribution be…

I state that CRISPR benefits researchers. However, that is still a niche benefit relative to the long term societal benefits we anticipate from CRISPR.