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How Much Vitamin D Is Too Much? A Case Report and Review of the Literature
71–80 of 149 posts
Re: How Much Vitamin D Is Too Much? A Case Report and Review of the Literature
#72Earlier quoted context omitted.
"megadosing" doesn't sound like its required for any reason unless you're malnourished, in which case your doctor would tell you how much to take. Adjusting your diet to not require "megadosing" due to malnourishment sounds like a better plan for long term health.
In addition, studies suggest that high levels of B6 and B12 in the blood are correlated with higher risk of certain cancers, such as prostate and lung cancer. In my opinion, having mild nutrient deficiency is not cause for alarm if you're a fully grown adult, and in fact, studies suggest that malnutrition might confer a longer lifespan.
I do not think those are good suggestions for the average person. I've read meta analyses about low caloric intake but not about malnutrition, which in general is a bad idea.
That being said most people who aren't severely restricting the types of food they eat, and eating healthy food, are unlikely to have significant malnutrition.
The lung cancer thing I remember was specifically smokers, so its not straightforward.
Re: How Much Vitamin D Is Too Much? A Case Report and Review of the Literature
#73The title doesn’t match the abstract. This isn’t a study of the tolerable upper limit of Vitamin D intake. It’s a case report of a single individual who was taking astronomical doses of Vitamin D with disastrous consequences. It’s certainly possible to take too much vitamin D without coming anywhere near the silly doses this person was consuming. Anyone taking aggressive vitamin D doses should invest in a vitamin D t…
> pop-science articles with unbridled enthusiasm for megadosing vitamins
That's an instant red flag for bullshit.
Re: How Much Vitamin D Is Too Much? A Case Report and Review of the Literature
#74"The patient had been assuming very high dose of cholecalciferol since 20 months (cumulative 78,000,000UI, mean daily 130,000UI), as indicated by a non-conventional protocol for multiple sclerosis." "This case confirms that vitamin D intoxication is possible albeit with a really high dose." This is a truly insane dosage but all this case says is that however created this protocol is dangerously incompetent.
> protocol
I wonder if that's an euphemism for "stuff they learned on youtube".
Re: How Much Vitamin D Is Too Much? A Case Report and Review of the Literature
#75Taking 130,000UI per day for 20 months is insane. Most of the over the counter doses are ~ 5000UI. I'm curious, as to what was the patients diet like? Vit D is a fat soluble vitamin and its my understanding that one needs to eat healthy fats for it to be absorbed by the body.
> Most of the over the counter doses are ~ 5000UI.
In what universe?
In this one, doses I've seen are around 1k UI.
Re: How Much Vitamin D Is Too Much? A Case Report and Review of the Literature
#76"The patient had been assuming very high dose of cholecalciferol since 20 months (cumulative 78,000,000UI, mean daily 130,000UI), as indicated by a non-conventional protocol for multiple sclerosis." "This case confirms that vitamin D intoxication is possible albeit with a really high dose." This is a truly insane dosage but all this case says is that however created this protocol is dangerously incompetent.
I guarantee if you get MS you’ll do some pretty crazy shit too, probably crazier than this.
What are you talking about? I have several family members with MS and they don’t do stupid shit they learned off YouTube.
Re: How Much Vitamin D Is Too Much? A Case Report and Review of the Literature
#77Another concern with Vit D supplementation is magnesium. As calcium and magnesium compete for absorption, Vit D’s effect of increasing calcium absorption can reduce magnesium absorption and lead to symptoms related to magnesium deficiency. I gather the toxic effects described in the article are partly due to extreme magnesium deficiency along with other effects - though magnesium or other effects aren’t mentioned in…
I happen to be taking magnesium for headaches and vitamin D because I'm deficient. Thanks for the info!
Re: How Much Vitamin D Is Too Much? A Case Report and Review of the Literature
#78The title doesn’t match the abstract. This isn’t a study of the tolerable upper limit of Vitamin D intake. It’s a case report of a single individual who was taking astronomical doses of Vitamin D with disastrous consequences. It’s certainly possible to take too much vitamin D without coming anywhere near the silly doses this person was consuming. Anyone taking aggressive vitamin D doses should invest in a vitamin D t…
Megadosing B12 (if your diet isn't already sufficient in it, which is common amongst certain vegan diets) is still a good idea, no? I recognize this might be the only exception.
I do that. I drink at least one 5-hour energy drink per day. I feel less depressed when I do that, but don’t try this at home without consulting doctor. I experiment with myself a lot and know my limits.
Re: How Much Vitamin D Is Too Much? A Case Report and Review of the Literature
#79Earlier quoted context omitted.
The trouble with Vitamin D is afaik, as with some other vitamins, that it is fat-soluble rather than water-soluble. So the excess of the Vitamin won't be flushed out through the urine - but rather accumulates in the fat. At some point this accumulation may lead to toxicity ("Hypervitaminosis D" [1]). Personally, I dose 4000-5000 IU D3+K2 in the darker seasons and that has been working well for me. Vitamin B12 is wate…
Do you dose the D3/K2 combo on a daily basis? I've got https://amzn.com/B075R56QCQ which i do ~3 times a week.
I did that every day and started to have muscle pains and weakness after a while. After doing some research and experimentations, turns out you also need to take magnesium if that happens.
Re: How Much Vitamin D Is Too Much? A Case Report and Review of the Literature
#80Earlier quoted context omitted.
Yeah, 130K IU / day is ~20x what's typically regarded as safe.
taking 20x the recommended dose of water (3-4 liters daily - 60-80 liters to compare) will kill you too.
...and people have died from it: https://en.wikipedia.org/wiki/Water_intoxication