Earlier quoted context omitted.
Difference is, the discovery of quantum mechanics did not require billion-dollar investment in equipment and manpower (not until work began on nuclear weapon, anyway). Besides, current research in high-energy physics, while being expensive, only brings scientific value and not much at all in the way of practical application (except, perhaps, as a side-effect of building more and more sophisticated equipment - but tha…
How can you be sure that the new science won't have any practical applications?
Nobody is sure about anything. Nobody denies that high-energy physics might one day bring great things. The problem is cost. Other areas of science are much more likely to bring great things with far less money. If tens of billions are to be spent on a bigger microscope, let it be one that will give us better solar panels, or a direct treatment for viruses. Polishing the details of the standard model can wait.