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Bosch develops rapid test for Covid-19

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Re: Bosch develops rapid test for Covid-19

#71
post #63

Is not ROCHE systems more performants https://www.roche.com/media/releases/med-cor-2020-03-13.htm ?

From your link:

”The widely available Roche’s cobas 6800/8800 Systems, which are used to perform the cobas SARS-CoV-2 Test, provide test results in three and half hours and offer improved operating efficiency, flexibility, and fastest time-to-results with the highest throughput providing up to 96 results in about three hours and a total of 384 results for the cobas 6800 System and 960 results for the cobas 8800 System in 8 hours. The test can be run simultaneously with other assays provided by Roche for use on the cobas 6800/8800 Systems.”

Re: Bosch develops rapid test for Covid-19

#72
post #61

How is this better than Open qPCR which is 3-times less expensive and can give a test result in 1 hour instead of 2.5 hours?

This is just another test cardridge available for the existing on-site lab machine. The idea is that health-practitioners with access to the device can now test on premise, instead of sending samples to the lab. I can't image a lot local doctors have access to qPCR, where this device is useful for all kinds of other test.

Re: Bosch develops rapid test for Covid-19

#73
This is fine, but it is yet another molecular test. What we need now are serology tests. They are faster, cheaper, easier to execute (blood-based), can detect cured patients, and can scale to the population of a country.

Serology tests are already used in several countries in Asia, I have little doubt they will arrive in Europe and the US soon-ish.

Re: Bosch develops rapid test for Covid-19

#74
post #6

> Up to 1,000 tests per day on just 100 devices So.. 10 tests per day per device? That doesn't sound THAT impressive.

yeah that's bad marketing but who needs marketing these days.

their advantage seems to be that they don't need extra personell to run , so anyone with sufficient safety precautions could use them in a hospital

Re: Bosch develops rapid test for Covid-19

#75
post #3

It all sounds impressive to me: >In various laboratory tests with SARS-CoV-2, the Bosch test delivered results with an accuracy of over 95 percent. I've read a lot of report on the current tests for SARS-CoV-2 having accuracy issues, does anyone know how 95% accuracy compares to the current methods?

Practicing hospital physician here. We never use the term "accuracy" to describe diagnostic tests, and whenever I see that term used, I'm very suspicious of the claim being made. In other words, this Bosch announcement can probably be ignored. We use the terms "sensitivity" and "specificity" to describe diagnostic test performance, and never to my knowledge talk about a test's "accuracy." Usually accuracy refers to t…

These terms don't translate very well on an International market. Bosch probably chose its terminology to suit its plans to market these devices outside the Anglo-sphere, as well...

Re: Bosch develops rapid test for Covid-19

#77

Sounds really impressive, but writing "1,000 tests per day with just 100 devivces" is really marketing BS I think. They should've just written "10 tests per day per device".

"Up to" is a synonym for "not more than but probably fewer".

So it doesn't really say how many tests it can process in a real-world setting.

Re: Bosch develops rapid test for Covid-19

#78
post #73

This is fine, but it is yet another molecular test. What we need now are serology tests. They are faster, cheaper, easier to execute (blood-based), can detect cured patients, and can scale to the population of a country. Serology tests are already used in several countries in Asia, I have little doubt they will arrive in Europe and the US soon-ish.

In Italy they claim to have developed such a test which is based on blood and takes only 15 minutes.

https://www.vivachek.com/vivachek/English/prods/prod-covid19...

Re: Bosch develops rapid test for Covid-19

#79

Earlier quoted context omitted.

So would sensitivity be the percentage of infected people who test positive and specificity be the percentage of non-infected who test negative (i.e. sensitivity = (1 - false negative probability) and specificity = (1 - false positive probability))?

Yes. The intuitive way I try to remember it is to think that, in just plain English, "How sensitive is this thing?" means "How likely is it to detect whatever it's supposed to detect?" (e.g.: How likely is this security camera to detect movement?)

"Sensitivity" is an inaccurate term, since for non-native English speakers, it could be misinterpreted as a term to mean some kind of emotional response.

"Accuracy" is a bit more scientific- leaning and therefore easier to translate.

Remember, COVID-19 is a global phenomenon, its not just relegated to the Anglo-sphere. Bosch, being a German company, is probably a bit sensitive to the accuracy of translations that will be needed to market this thing effectively around the world .. ;)

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