Earlier quoted context omitted.
For about a year or so now Ive been wanting to make a game about science. It'd basically be a research and discovery simulator, and there would be a free-play mode. Some of the knobs would be # of required replication, required p-value and how good people are at generating hypothesis. I think it'd be eye opening.
There is a "people will mostly replicate/extend articles about X, and ignore articles about Y" (groupthink) effect that I imagine is also very relevant.
It’s not just p=0.048 vs. p=0.052
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Re: It’s not just p=0.048 vs. p=0.052
#72> To say it again: it is completely consistent with the null hypothesis to see p-values of 0.2 and 0.005 from two replications of the same damn experiment. I don't really follow this. Could someone clarify what is meant here? At what point would this author say something is not consistent with the null hypothesis?
Re: It’s not just p=0.048 vs. p=0.052
#73Related, about p-values: > Here's the problem in a nutshell: If you run 1000 experiments over the course of your career, and you get a significant effect (p > […] However, this is a statement about what happens when the null hypothesis is actually true. In real research, we don't know whether the null hypothesis is actually true. If we knew that, we wouldn't need any statistics! In real research, we have a p value, a…
That's not what the p-value means. It means that if you run 1000 of the experiments in a universe in which the hypothesis is false, around 50 of them will confirm the hypothesis anyway. If the hypothesis is true, then there are no false positives; all positives confirm the hypothesis. In a universe in which the hypothesis is true, there can only be false negatives. "False positive" means that the effect or condition…
Re: It’s not just p=0.048 vs. p=0.052
#74Earlier quoted context omitted.
So by this logic "it is completely consistent with the null hypothesis to see p-values of 0.00000001 and 0.99999999 from two replications of the same damn experiment"? At which point, what is even the point of this statement?
My understanding (Someone please correct me if I'm wrong) is that while the values can range from limx->0 and limx->1 , the actual distribution will be skewed in cases where it is statistically significant. E.g. If you repeat the experiment 100x you could find a p=.999999 but more likely they'll be close to .05 (or whatever alpha you choose)
The distribution will be different when then true hypothesis is not true (but you may also get non-significant results even if the null hypothesis is not true).
I’m not sure if that’s what you mean by “the actual distribution will be skewed in cases where it is statistically significant.”
Re: It’s not just p=0.048 vs. p=0.052
#75> To say it again: it is completely consistent with the null hypothesis to see p-values of 0.2 and 0.005 from two replications of the same damn experiment. I don't really follow this. Could someone clarify what is meant here? At what point would this author say something is not consistent with the null hypothesis?
He is coming at that conclusion from a Bayesian point of view to statistics. He is seeing the p-value as a random variable that can take values from 0 to 1 and follows some distribution. Under these hypotheses, observing a p-value of 0.20 and 0.005 is completely reasonable even if unlikely. Those are just two draws from a random variable. Edit. Under Bayesian statistics testing the null hypothesis is a moot point as…
That is the frequentist point of view!
Re: It’s not just p=0.048 vs. p=0.052
#76Earlier quoted context omitted.
My understanding (Someone please correct me if I'm wrong) is that while the values can range from limx->0 and limx->1 , the actual distribution will be skewed in cases where it is statistically significant. E.g. If you repeat the experiment 100x you could find a p=.999999 but more likely they'll be close to .05 (or whatever alpha you choose)
If the null hypothesis is true the p-value is distributed uniformly in [0 1] (at least ignoring discrete data, composite hypothesis and other cases which are not easy). The distribution will be different when then true hypothesis is not true (but you may also get non-significant results even if the null hypothesis is not true). I’m not sure if that’s what you mean by “the actual distribution will be skewed in cases w…
Re: It’s not just p=0.048 vs. p=0.052
#77Earlier quoted context omitted.
What he says is (I gather) worse: those events are only separated be 1.1std deviations, which is little.
I think that's what he's saying too, but what is that supposed to show? Is he arguing against some claim that every interval of 1 standard deviation is equally significant? Did anybody make this claim? So far as I know, nobody considers (say) a 6-sigma effect to be 6 times stronger than a 1-sigma effect...
Re: It’s not just p=0.048 vs. p=0.052
#78Re: It’s not just p=0.048 vs. p=0.052
#79Re: It’s not just p=0.048 vs. p=0.052
#80Put a Number on It! did a piece a while ago going through some psychology pieces that were part of a replication effort. They found that half failed to replicate but that people in a betting market could often tell which ones were going to replicate or not. The author also did a blind test himself and was also able to guess which ones would replicate. He laid out several rules of thumb, most significantly to the arti…
This is true in more than just psych. A strategy for systems papers is to select the system that is second on the graphs. The author's results are not trustworthy, but the second place system was usable and ran reasonably well in the hands of somebody other than the original author.