i recently went on a little exploratory mission to see what the working explanation is for how the pores actually get blocked, and then swell. it sounds like the process, in super detail, is not well understood. from what i could gather, sebaceous glands get blocked, and the sebum they secrete starts to pool in the duct around the follicle, under the skin. the sebum creates an ideal environment for a bacteria called…
I also learned recently that sebum production -- and inflammation -- are both complex mechanisms. As with most regulatory systems I wouldn't be surprised if they were linked in some way. But obviously I don't want to claim this in some hand-wavy way. Can you share any reading material you found when exploring the topic?
I have recently started Spironolactone for various PCOS symptoms, including acne vulgaris, so it's of interest to me