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Ask HN: What's a promising area to work on?

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Re: Ask HN: What's a promising area to work on?

#691
post #114

I see a huge trend coming in “DIY Medicine”. Doctors, insurers, and the FDA are way too expensive for mere gatekeeping, and technology is developing new treatments and dropping equipment costs an order of magnitude faster than they can respond. For example, I can buy all of the equipment necessary for a PRP injection for less than the cost of a single treatment, and the doctor that does it knows no more about how to…

This got me thinking about ideas for a product that would work internationally vs. just in one country and if that signal means much about the viability of a product. In terms of work being "promising", wouldn't I want to takle a global problem, not one unique to a specific country?

I see this trend strongest in Asia right now.

Re: Ask HN: What's a promising area to work on?

#692

Crypto. And no, I don't mean applying blockchain to everything, or internet money that just goes "up and to the right". I mean the new applications of distributed systems research and cryptographic primitives that allow for highly composable, highly trustworthy, permissionless, autonomous machines. MakerDAO, Arweave, the whole field of open finance (aka "DeFi"), and so many others collectively are very likely to chan…

I think the people behind "trustlessness" should have chosen a better word. When people that are not familiar with crypto hear trustless, they can associate the solution with the common definition: "not worthy of trust; faithless; unreliable; false". I.e. the solution isn't reliable. I realize that the people behind it are trying to apply the world trustless to the problem they are solving, but that is definitely not…

Some people are calling it web3.

https://web3.foundation/about/

Re: Ask HN: What's a promising area to work on?

#693

Earlier quoted context omitted.

> The most pressing problem for humanity is global climate disruption. I don't believe most would agree here. There are a lot of problems humanity faces, and humanity is a lot of different people. Those still living in extreme poverty today probably don't care about our worries of climate disruption. > Arguably, working on anything that doesn't help there is not just wasted effort, but actively harmful. Why is this?…

> Those still living in extreme poverty today probably don't care about our worries of climate disruption. Tell that to 100Million people in poverty in Bangladesh that will become climate refugees if the sea level rises in any meaningful way. In the west, sea-side living is a privilege for the richest. And sea level rise is mostly ignorable with the virtue of new seawalls. In the developing world, the most poverty-st…

You're right about those people, but I'm not talking about them. There are people living in extreme poverty today who won't even be alive anymore by the time sea level rise causes a problem.

Who are we to claim that climate change is the most pressing issue facing humanity, when much of humanity faces unrelated life threatening issues?

Re: Ask HN: What's a promising area to work on?

#694
While this thread is still popular, I would like to see some renewed innovation in “management science”, as in, how to set up a large modern organization for sustainable success. Like, install an app and just follow the plan. No more management shakeups and genius dear leaders.

Re: Ask HN: What's a promising area to work on?

#695

Earlier quoted context omitted.

Very common when you do tech work in a non-tech industry. Comes up a lot with coding-inclined mechanical engineers. Zed Shaw's words are really true: > Programming as a profession is only moderately interesting. It can be a good job, but you could make about the same money and be happier running a fast food joint. You're much better off using code as your secret weapon in another profession. People who can code in th…

I don't buy it. There are tons of software "engineers" who try to escape fintech for FAANGs or even startups, coming from top tier firms like Goldman and McKinsey. Likewise, bioinformatics generally pays a lot less than traditional SWE roles. So what I have seen is the exact opposite in practice: people with minimum coding skills in other fields trying to jump into tech firms.

I suppose it's hard to match the salaries at The Big Corps working in other industries. Still, outside of software companies, people think I'm basically a wizard for doing simple things, like automatically generating climographs from JSON files. I just don't get that kind of positive reinforcement from software people. I think it's just more enjoyable to be the hacker rather than a hacker.

Re: Ask HN: What's a promising area to work on?

#696
post #665

Platforms that enable a diaspora of small businesses to operate as effectively as large organizations with minimal startup cost. Why build a massive services organization when you can enable and finance a takeover by a multitude of smaller players?

This is interesting. Do you have any examples in mind that achieve this? Whether in particular niches or solving common problems throughout small business?

Re: Ask HN: What's a promising area to work on?

#697
post #679

I listened to Robert Green's talk at Google recently [0] He proposes the following idea: - Everybody born within 22 years of each other belong to a "generation" - Generations follow a cycle: - There is a rebellious generation - The next generation is trying to keep the ideals of the rebellious generation alive - The third generation is very conservative - The fourth generation is a "crisis" generation that will event…

He was probably drawing from the Strauss-Howe generational theory[1], which is more than 20 years old now. He (or you) should have credited the original thinkers for these ideas. Their 1997 book "The Fourth Turning" is considered pseudoscience but nonetheless great food for thought, imho. Note that the cycle may sometimes be shorter (3 gens) or longer (5). It's not really a theory, more like empirical observation. Un…

The idea of cycles in social history is as old as the hills. It's possible your claim that he drew from Strauss-Howe is correct, but while they may have packaged the idea in a distinctive way, it has a long history.

https://en.m.wikipedia.org/wiki/Social_cycle_theory

Re: Ask HN: What's a promising area to work on?

#698

Earlier quoted context omitted.

> The most pressing problem for humanity is global climate disruption. I don't believe most would agree here. There are a lot of problems humanity faces, and humanity is a lot of different people. Those still living in extreme poverty today probably don't care about our worries of climate disruption. > Arguably, working on anything that doesn't help there is not just wasted effort, but actively harmful. Why is this?…

> Those still living in extreme poverty today probably don't care about our worries of climate disruption. Tell that to 100Million people in poverty in Bangladesh that will become climate refugees if the sea level rises in any meaningful way. In the west, sea-side living is a privilege for the richest. And sea level rise is mostly ignorable with the virtue of new seawalls. In the developing world, the most poverty-st…

[dead]

Re: Ask HN: What's a promising area to work on?

#699
post #542

Earlier quoted context omitted.

The most pressing problem for humanity is global climate disruption. Arguably, working on anything that doesn't help there is not just wasted effort, but actively harmful. Wind, solar power, energy storage still have huge room for improvement. Direct solar or wind -> liquid fuel will be essential to adapting fast. Windmills can drive production of liquid ammonia on farms (needing only air and water inputs), for use d…

> Without massive progress in the next decade, civilization will probably collapse by 2035. This is a joke not backed by any scientific consensus or evidence. Maybe some more instability in some countries, but nothing close to the collapse of civilization.

Who is still waiting for the ice age promised to us in the '70s?

Re: Ask HN: What's a promising area to work on?

#700
post #677
post #268

Earlier quoted context omitted.

"Doctors know that the price of the most effective treatments may not sustain their profession." This is not really a fair assessment. The most cost effective treatments can be self administered. But if you are coming in to see me because of persistent knee pain, more often that not you have already tried tylenol and over the counter nsaids (ibuprofen, etc.), and your pain has been persistent. The next set of treatme…

I was including the price of the ultrasound imaging machine. And I’m not talking about Tylenol either, which is a harmful and oversubscribed drug anyway. Example: I’ve been given a choice: surgery that includes removal of hip cartilage, or nothing. But there are many natural growth factors that have shown excellent cartilage regeneration. PRP wouldn’t be among my first choices, but as an example, it’s better than not…

Maybe see a better doctor. If you’ve self diagnosed and researched a treatment yourself, they should be understanding. However, without high evidence data or guidelines, you could sue them and they woruld have no leg to stand on, so I’m sure there’s a component of defensive medicine.
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