Everyone has their own unique heartbeat signature. What we need is a way to hear that heartbeat, and if its not the right signature: erase/destroy/etc.
First security in layers is the best option.
1. USB HID watcher that shuts down system when plugged in. If we use a mouse, we can exclude that. But any other HID, shutdown -r now.
2. Fingerprint scanner. It's not foolproof, but does make duplicating fingerprints a pain if you dont cooperate. And jailcells usually have concrete. No more fingerprints :)
3. Most laptops have webcams built in. I'm looking in OpenCV FaceRecognizer class to see how it works, and if it's viable for fingerprinting a user. We could also do other checks, like 3d facial recognition over multiple video frames.
4. We could also potentially use the accelerometer built in laptops. When others have made a sshd knock script, we could provide a knock script to the physical device.
5. Lock on ac power removal. Simple and effective, unless the enemy has AC separation tools.
There's a few ideas. And of course, mix in live filesystems in ram, or virtualbox funniness, and you're in business.