Hacker News Board Hacker News, browsed like a classic message board
Live data from Hacker News

Tramadol Is Not a Natural Product After All

pipeline.corante.com

Post reply on HN
Print view View original

61–70 of 121 posts

Re: Tramadol Is Not a Natural Product After All

#61

Post by sillysaurus3 »

throwaway_yy2Di wrote: post #44

[off topic] Wow, his last post created some bizarre drama on Reddit: http://pipeline.corante.com/archives/2014/09/12/thiola_retro... His criticism of a biotech CEO provoked a Reddit thread with two thousand comments, and the CEO showing up to write responses. And controversially the whole thing was removed by moderators, and Dr. Lowe briefly banned from the site.

Would you mind linking to the thread? I know it's been removed, but I'm curious which subreddit that happened in.

Also, did anyone ever explain why he was shadowbanned? Only Reddit admins can shadowban someone, and I thought they only issued bans for vote manipulation, not for causing controversy.

Re: Tramadol Is Not a Natural Product After All

#62

Post by DanBC »

sillysaurus3 wrote: post #61
throwaway_yy2Di wrote: post #44

[off topic] Wow, his last post created some bizarre drama on Reddit: http://pipeline.corante.com/archives/2014/09/12/thiola_retro... His criticism of a biotech CEO provoked a Reddit thread with two thousand comments, and the CEO showing up to write responses. And controversially the whole thing was removed by moderators, and Dr. Lowe briefly banned from the site.

Would you mind linking to the thread? I know it's been removed, but I'm curious which subreddit that happened in. Also, did anyone ever explain why he was shadowbanned? Only Reddit admins can shadowban someone, and I thought they only issued bans for vote manipulation, not for causing controversy.

He used multiple accounts to vote-ring.

Re: Tramadol Is Not a Natural Product After All

#63

Post by tjradcliffe »

pbhjpbhj wrote: post #37
80ProofPudding wrote: post #12

Earlier quoted context omitted.

Agreed. "Organic" is pretty widely abused, too - want to drink some crude oil? It's organic...

Crude oil is [primarily] organic if your context is [petro]chemistry. It's not an organic foodstuff however. Shock, horror, words have contexts which cause them to mean different things. Why is it that you don't wish people to know where their food has come from and how it has been produced. What is the problem with that for you? If you don't care that your children's food is saturated with growth hormones, fungicide…

"Shock, horror, words have contexts which cause them to mean different things."

Dunno what his problem is, but my problem is the context in which "organic" gets used with respect to foods: a massively expensive, misleading, anti-science marketing campaign by huge corporations intent on profiting from people's mistaken belief that "organic" products are--by virtue of being "organic"--healthier or better for the environment.

Since the people behind this huge corporate marketing campaign are also promulgating lies about GMOs in an attempt to force labeling on them and prevent their development, your claim "there's no detriment" to others from those who support them is false.

Re: Tramadol Is Not a Natural Product After All

#64

Post by throwaway_yy2Di »

sillysaurus3 wrote: post #61
throwaway_yy2Di wrote: post #44

[off topic] Wow, his last post created some bizarre drama on Reddit: http://pipeline.corante.com/archives/2014/09/12/thiola_retro... His criticism of a biotech CEO provoked a Reddit thread with two thousand comments, and the CEO showing up to write responses. And controversially the whole thing was removed by moderators, and Dr. Lowe briefly banned from the site.

Would you mind linking to the thread? I know it's been removed, but I'm curious which subreddit that happened in. Also, did anyone ever explain why he was shadowbanned? Only Reddit admins can shadowban someone, and I thought they only issued bans for vote manipulation, not for causing controversy.

It's linked in that blog post:

https://www.reddit.com/r/news/comments/2g43kw/a_generic_drug...

Re: Tramadol Is Not a Natural Product After All

#65

Post by throwaway_yy2Di »

DanBC wrote: post #62
sillysaurus3 wrote: post #61

Earlier quoted context omitted.

Would you mind linking to the thread? I know it's been removed, but I'm curious which subreddit that happened in. Also, did anyone ever explain why he was shadowbanned? Only Reddit admins can shadowban someone, and I thought they only issued bans for vote manipulation, not for causing controversy.

He used multiple accounts to vote-ring.

What's your source?

Re: Tramadol Is Not a Natural Product After All

#66

Post by GigabyteCoin »

DanBC wrote: post #62
sillysaurus3 wrote: post #61

Earlier quoted context omitted.

Would you mind linking to the thread? I know it's been removed, but I'm curious which subreddit that happened in. Also, did anyone ever explain why he was shadowbanned? Only Reddit admins can shadowban someone, and I thought they only issued bans for vote manipulation, not for causing controversy.

He used multiple accounts to vote-ring.

I highly doubt that a doctor who was receiving massive traction on reddit would stoop so low as to fake-upvote his own article.

Re: Tramadol Is Not a Natural Product After All

#68

Post by gone35 »

rjurney wrote: post #14
alexjeffrey wrote: post #9

Earlier quoted context omitted.

more importantly, the use of "natural" to describe a product with the implication that it being synthetic would be a bad thing is a fallacy.

Still, there is something nice about a chemical appearing in nature. Gives evidence that it doesn't do batshit crazy things to life.

If by "batshit crazy" you meant toxicity, then yes that's clearly incorrect, as others have repeatedly pointed out. Perhaps you meant chemical affinity in some general way --eg homochirality, or presence of commonly targeted functional groups?

If so, note this is the exact opposite of 'biocompatible' in the usual sense (as in 'inert'): biosynthesized molecules evolved precisely to be exceedingly good at reacting/interfering with biological processes, not the other way around. So if anything, it would be evidence they could well do batshit crazy, unintended things to life --as they often do.

Re: Tramadol Is Not a Natural Product After All

#70

Post by tedunangst »

dbbolton wrote: post #50

>The farmers apparently take the drug themselves, at pretty high dosages, saying that it allows them to work without getting tiree. That's insane. Tramadol is among the worst painkillers to use recreationally, which is why it's often the next line of analgesic therapy after NSAIDs and before hydrocodone. It is a comparatively weak mu-opioid agonist, so the dose a person would have to take to get a prototypical opioid…

It doesn't sound like they're trying to get high, per se, just work harder without feeling it. A "recreational" dose would probably interfere with getting work done.
Post reply on HN