TL;DR: For those asking, "WHY?" : It's about control. Background: Every time there's a new forum site, people often ask, "why not just create a subreddit or facebook group, etc". That would save much code, debugging, & traffic/marketing. However, the reason people still create 3rd party forum sites is not out of foolishness. Rather, they are trying to control the community, & harvest the benefits of the community ove…
We Built a Hacker News for Biotech
61–70 of 86 posts
Re: We Built a Hacker News for Biotech
#62We see 1 or 2 of these "Hacker News for X" sites a month. Have any of you succeeded and developed a community beyond the spike of interest you received making the HN frontpage?
https://cryptanalys.is is my recently launched HN clone dedicated to cryptocurrencies, cryptography, privacy and security. My original submission was a complete dud without a single upvote ~23 days ago: https://news.ycombinator.com/item?id=7339368 I went to sleep feeling defeated after 2 months of work and went back to the drawing board in the morning. I've been experimenting with various forms of advertising over th…
"Soylent is a food substitute intended to supply all of a human body's daily nutritional needs, made from maltodextrin, rice protein, oat flour, canola oil, fish oil, and raw chemical powders." -Wikipedia
Re: We Built a Hacker News for Biotech
#63Any more science related news aggregates like this? F*ck it - list all the great aggregates like Hacker News.
Re: We Built a Hacker News for Biotech
#64Re: We Built a Hacker News for Biotech
#65I think the biggest problem with the homebrew biotech world right now is that even with the labs opening up, there's still such a barrier to entry. There's a "hello world" to biotech, no doubt; extract some DNA from strawberries or explore the tiny world with a consumer microscope. But then what? There doesn't seem to be much potential mid-tier work to be done in biotech. In contrast with software where there is a ve…
For thousands of years, humankind has used biotechnology in agriculture, food production, and medicine.
http://en.wikipedia.org/wiki/Biotechnology
It seems to me any farmer or homemaker can do "biotech." The question I have is not how can it be done but how do you market it? It seems to me the issue is one of getting taken seriously. The barrier to "entry" is not that high. You can do "biotech" in your kitchen or backyard. But finding a way to reach consumers, finding a way to monetize it, finding a way to convince people you aren't one of those folks wearing a tinfoil hat with a diagnosis of "batshit insane" -- those are challenges.
Re: We Built a Hacker News for Biotech
#66I really want this to work well.
I need an HN for biotech.
Re: We Built a Hacker News for Biotech
#67Earlier quoted context omitted.
Remember when it used to be "Digg for X"? I kinda thought subreddits took a lot of the wind out of those sails.
I think there is something about the HN layout that makes it feel more "homegrown", which has no ads or images at all. Kind of reminds me of an old-timey newspaper, or the WSJ "What's News." Not saying it can't be improved.
A lot about hacker news could be improved, I think, like adding a JSON api by default and being able to control the depth level of comments. More importantly though, I think the simple format facilitates discussion a lot better than the noisy, avatar-riddled nightmares like phpbb, etc.
Re: We Built a Hacker News for Biotech
#68Earlier quoted context omitted.
zerops comment has a list.
That comment seems to be dead.
Edit: Apparently not. If anyone wants to see his post, they need to turn on show dead.
Re: We Built a Hacker News for Biotech
#69Cool, I was thinking about one for a while, but I see one problem. Harlem Biospace doesn't really scream "Hacker News for Biotech". Not intended to offend the Manhattan based incubator that charges $1k for a desk/month.
Pricing aside, I disagree: YC is in part a startup incubator, no? Those driven to work in an incubator space are precisely the kinds of people who can benefit from a "Hacker News for..." site. That said, there are many biotech incubators across the country, so perhaps this isn't my/your favorite. But even so, I commend them for getting the site off the ground.
[Update: Before you read this wall 'o text, please consider the comment in the context of the update at the bottom.]
I disagree, YC is not an incubator. Well, to be fair, incubator is kind of a nebulous term.
I define incubator as: "entity that charges entrepreneurs for privileged access to ostensibly valuable [x y z]" or "entity that hires so called 'entrepreneurs in residence' to build companies under its roof in exchange for exorbitant equity."
YC is only superficially similar to whatever you would describe Harlem Biospace as.
The essential difference is in how the two types of entities derive value from their offering.
The distinction is that [YC, 500S, TechStars] invest in the upside of companies. Harlem [and its ilk] make money per unit of offering sold [units of monthly [x y z] access].
The reason "incubators" (the ones that charge entrepreneurs) are usually worse than the YC's of the world is because they adversely select for all the wrong things, as a side effect of their design.
Since an incubator ostensibly helps startups win big, why charge per unit [startup]? Why not invest in portfolio upside?
Per unit charges seem to be a good way of making money in the near term, at a constant rate (might not be sustainable if companies don't succeed in the long run.)
Upside investment seems like a good way to make money in the long run (assuming you are sufficiently able to (a) pick the right startups and/or (b) influence them to succeed.)
So investment seems to signal that you believe that you can do (a) and/or (b).
Sure, an investment portfolio may lose money on most of the companies. However, if it has a group of companies of sufficient expected success, one will likely reap massive returns.
If the value investors provide is worth enough to attract the right kinds of founders, the expected value of investing in entrepreneurs should exceed the expected value of charging entrepreneurs.
In the long run, charging per unit of offering, may signal that the long-term value of the seller's [x y z] offering is relatively low when compared to entities that are willing to invest in entrepreneurs.
Basically, if you value the unit cost higher than the investment return you are signaling that you (a) can't pick good startups and/or (b) you can't help a sufficient number succeed.
What kind of entrepreneur would want to go to that entity?
Since portfolio companies tend to return value later in their timeline, long-term value of offering is what matters. The YC's of the world are willing to eat the short-term costs and bet that they will influence some startups to return big.
The Harlem's of the world are making a constant per unit income, but are unwilling to bet on the long tail equity upside.
These incubators are not equivalent to [YC, 500S, TechStars], they are glorified co-working spaces.
[Update: If you've read this far, please see the discussion further on the thread. I unfairly characterized Harlem as an "incubator". Harlem Biospace certainly offers value. I do stand by my comment on "incubation" in the context of consumer internet companies. It's a different ball game for capital intensive industries. One aspect of Harlem is that it is affordable lab space that is group funded. Undeniably important.]
Re: We Built a Hacker News for Biotech
#70Earlier quoted context omitted.
Pricing aside, I disagree: YC is in part a startup incubator, no? Those driven to work in an incubator space are precisely the kinds of people who can benefit from a "Hacker News for..." site. That said, there are many biotech incubators across the country, so perhaps this isn't my/your favorite. But even so, I commend them for getting the site off the ground.
> Pricing aside, I disagree: YC is in part a startup incubator, no? [Update: Before you read this wall 'o text, please consider the comment in the context of the update at the bottom.] I disagree, YC is not an incubator. Well, to be fair, incubator is kind of a nebulous term. I define incubator as: "entity that charges entrepreneurs for privileged access to ostensibly valuable [x y z]" or "entity that hires so called…
I'd like to point out, however, that there several thriving biotech incubators around the country. Surely the demand must be coming from somewhere when tenants must be found to pay the bills. Indeed, I think the startups that enter an incubator space are well aware of the rent prices, and do so to to take advantage of the certified lab space provided which is impractical to build on one's own.
A takeway from all this, for me, is that I'm wondering what one could do to make a biotech-focused YC a workable model. Unfortunately, the (comparatively) glacial pace of biotech startups dampens a lot of enthusiasm.