TL;DR: Core ingredient in most anti-bacterial soaps, triclosan, may or may not work. FDA asking manufacturers to prove it works. Scientists say that these chemicals may act as hormone disruptors, pointing to a link between triclosan exposure and allergies.
> may or may not work That's not accurate. It does work, as in, it does kill bacteria. The question is if this killing has any value. i.e. does it actually prevent illness. It's pretty clear that in a hospital or nursing home setting triclosan is worth it. It's not so clear if it's worth it in the home. Then there is a secondary question of does it cause resistance in the bacteria, which then causes it to be less eff…
This has been seen with C. difficile infections that occur after broad-spectrum antibiotic administration. These infections are 50% fatal when treated with more antibiotics. Use of fecal transplants, aka the poop of a healthy person put it into the c. difficile patient's stomach, seems to drop that fatality rate to less than 1%. The impact appears to be from the reestablishment of bacterial homeostasis in the gastrointestinal tract.
Study is still ongoing on the broad efficacy of this method, but regardless there is at the very least a substantial subset of the population who are demonstrably at risk from the loss of native flora due to bactericidal treatment.