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Melatonin impairs morning cognition in healthy young adults (2023)

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Re: Melatonin impairs morning cognition in healthy young adults (2023)

#61
As with so many experiments, the study itself is clear and testing something valid, but when it gets shared somewhere like reddit/HN/Facebook etc. everyone takes the broadest possible, unintended reading.

- study: we tested specifically healthy young adults and found melatonin may have a negative effect on this cohort. We make zero claims about any other cohort.

- every lay person reading the study, of any age: scientists just proved melatonin makes me dumb in the morning! Oh no!

Re: Melatonin impairs morning cognition in healthy young adults (2023)

#62
post #51

Tangentially: as a 'young adult' I was a typical 'night owl'. Cognitivly I peaked between 10pm and 3am, typically slept from 4am to 11am. When I got kids and a more 'regular' job, I was forced to change to a more normal schedule. The transition from 'owl' to 'lark' was not easy. It took about 7 years. These days, I peak 7am to 1pm.

Interesting. I’m also a night owl who struggled waking up like an early bird. Was the transition and efforts worth it? Recently I tried to find a better schedule other than spending another X years fighting my biological clock

Eliminate all screens after sundown. It's literally the nr 1 reason why people struggle. I used to as well (I could easily work in front of a monitor until 4am without getting tired with no coffee or anything). After that, avoid any bright white lights in the evening (usually kitchen/bathroom). It's not always possible, depending on your work and place of living and especially while travelling. I ended up getting extreme blue light filtering glasses too (make sure they cover your eyes fully so light doesn't leak in from the side). Looks ridiculous, but that helped a lot. Finally, add a wind down routine that does not involve any kind of mental or physical excitement. For me it was as simple as walking around the block for 10-15min. But it can be anything that doesn't stimulate you in any way. You can try to sit in the darkness and meditate.

You will not just sleep better, you will have no issues sleeping at night and getting up in the morning. Downside is that you will definitely be awake once the sun rises (sucks in summer if you live far from the equator) and if you shut the blinds and have no automatic opener you are very likely to oversleep. Tuning your body to the solar day has pros and cons.

Re: Melatonin impairs morning cognition in healthy young adults (2023)

#63

Earlier quoted context omitted.

Coffee isn't mentioned. Morning cognition could be impacted by whether subjects take caffeine before starting tasks.

Good point. For regular coffee drinkers, testing an hour after waking without their usual caffeine could be its own cognitive impairment experiment

It’s hard to do a blind test on yourself.

But I accidentally ran this test on myself recently and didn’t realise until I got home and found my full cup on the bench.

It was disturbing to know how much I need it.

Re: Melatonin impairs morning cognition in healthy young adults (2023)

#64
post #51

Tangentially: as a 'young adult' I was a typical 'night owl'. Cognitivly I peaked between 10pm and 3am, typically slept from 4am to 11am. When I got kids and a more 'regular' job, I was forced to change to a more normal schedule. The transition from 'owl' to 'lark' was not easy. It took about 7 years. These days, I peak 7am to 1pm.

Interesting. I’m also a night owl who struggled waking up like an early bird. Was the transition and efforts worth it? Recently I tried to find a better schedule other than spending another X years fighting my biological clock

You have to completely stop caffeine, best to cut nicotine too. It's worth it. Watch out for caffeine In cola etc.

Re: Melatonin impairs morning cognition in healthy young adults (2023)

#65
post #27

Earlier quoted context omitted.

Long ago when I paid attention to this, the wisdom was to watch out because most melatonin pills are targeted to geriatric patients. Old folks need a significant boost to their melatonin to deal with eroding sleep quality, not a little hit of it. So as a 30 year old or younger you want a fraction of what grandad is taking.

You'd expect the standard OTC dose to be a sensible starting point, not potentially several times more than a younger person needs

You wouldn’t, if you remembered that medically speaking, younger people “needing” melatonin pills has been pretty fringe until very recently, and the number of young people who need it is still comparatively small.

You can find smaller pills. But you might have to try several chains or order online to get them.

Re: Melatonin impairs morning cognition in healthy young adults (2023)

#66
post #27

Earlier quoted context omitted.

Long ago when I paid attention to this, the wisdom was to watch out because most melatonin pills are targeted to geriatric patients. Old folks need a significant boost to their melatonin to deal with eroding sleep quality, not a little hit of it. So as a 30 year old or younger you want a fraction of what grandad is taking.

You'd expect the standard OTC dose to be a sensible starting point, not potentially several times more than a younger person needs

There is a rumour that the high doses are because the correct dose was under patent.

I can only find that in a comment here: https://slatestarcodex.com/2018/07/10/melatonin-much-more-th... but I could have sworn it was in the main article when I first read it. (If so that makes it less likely, because the author revises his articles for correctness)

That (albeit long) article is worth reading. For example, it explains that melatonin is a phase signal, so being saturated with too much melatonin actually makes the signal less clear (as well as potentially causing other issues).

Re: Melatonin impairs morning cognition in healthy young adults (2023)

#67
post #51

Earlier quoted context omitted.

Interesting. I’m also a night owl who struggled waking up like an early bird. Was the transition and efforts worth it? Recently I tried to find a better schedule other than spending another X years fighting my biological clock

You have to completely stop caffeine, best to cut nicotine too. It's worth it. Watch out for caffeine In cola etc.

Why is it worth it? Why are you fighting against your natural circadian rhythm? We still all got 24 hours right?

My background is that as the poster above, I have always been a night owl, with the ability to function and wake up earlier if I need to.

For years I have tried to change it because of beliefs like yours that it was "worth it". Whenever I tried to change it I would feel unergetic, crappy and unmotivated. I would stumble on words and have terrible sleep. Yes, I tried to stop caffeine, use candle light only, ton of supplements. Nothing worked.

Since then I have accepted I'm a night owl, and I should embrace it. I have never felt better since the day I have decided to stop fighting it.

The 6AM hustle seems amazing in theory but at the end of the day we all only got 24 hours.

Re: Melatonin impairs morning cognition in healthy young adults (2023)

#68
post #51

Tangentially: as a 'young adult' I was a typical 'night owl'. Cognitivly I peaked between 10pm and 3am, typically slept from 4am to 11am. When I got kids and a more 'regular' job, I was forced to change to a more normal schedule. The transition from 'owl' to 'lark' was not easy. It took about 7 years. These days, I peak 7am to 1pm.

Interesting. I’m also a night owl who struggled waking up like an early bird. Was the transition and efforts worth it? Recently I tried to find a better schedule other than spending another X years fighting my biological clock

As a night owl who tried to fight it for too long my advice is don't change your natural circadian rythm. For some reason hustle influencer culture made us believe we should wake up at 6AM for a productive day. We all have 24 hours, just do what works for you.

Most of Europe doesn't wake up that early. Only the US is obsessed with 4AM hustle culture. Stop that!

I tried to change my sleep for 10 years and for the last 2 I have been embracing the night owl rhythm. And yes I have kids and an amazing partner.

Re: Melatonin impairs morning cognition in healthy young adults (2023)

#69
Surprisingly, one thing that tremendously helped my sleep quality, and several persons around is wim hof breathing.

I used to do it in the morning, and my brother recommanded I'd switch to just before sleep.

The difference is stark in effects, and you fall asleep like a baby even when stressed, using red light, with heat waves, etc...

Given it's free and don't have the side effects of regular melatonin supplement, I would encourage every one to give it at least a one week trial.

Re: Melatonin impairs morning cognition in healthy young adults (2023)

#70
post #51

Earlier quoted context omitted.

Interesting. I’m also a night owl who struggled waking up like an early bird. Was the transition and efforts worth it? Recently I tried to find a better schedule other than spending another X years fighting my biological clock

It was not an option. Kids need a regular schedule with school and things. It was rough though. I did not ever drink coffee before that time, but starting then I needed several cups just to avoid accidents in the morning.

School starts way too early. That's something we need to change. I grew up in Europe and school started at 9AM. Which allowed for an 8AM wake up.

Unlike here where my kids need to wake up at 6AM. Absolutely ridiculous

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