Earlier quoted context omitted.
Itanium is yet another example of how difficult it is to fight software ecosystem momentum. It had potential but until you have an easy transition path, few will consider it. Apple figured that out during the 68K > PPC > X86 > ARM transitions.
Itanium 1 had hardware x86 compatibility and Itanium 2 had software x86 emulation just like Apple. It wasn't enough.
Apple succeeds on their hardware transitions exactly because there isn't a clones market.