Live data from Hacker News

Scientists reverse brain aging, with a nasal spray

stories.tamu.edu

61–70 of 93 posts

Re: Scientists reverse brain aging, with a nasal spray

#61

Earlier quoted context omitted.

“The most surprising part? It all happened within weeks and lasted for months.” That’s an AI tell. It may not be entirely LLM-generated, the various direct quotations help a lot, but there are touches that definitely feel like an LLM had a hand here.

That's not an "AI tell". If you read anything in recent decades, this is a turn of speech human writers wrote for ages and still write.

Anybody who still writes using their own mind has stopped using that pattern, along with others. "The thing nobody tells you:" is no longer used by decent writers.

Re: Scientists reverse brain aging, with a nasal spray

#62

That's exactly what I want: immortal mice!

You joke, but rodents make great pets, because they are very social and have a range of personalities, but most only live a few years. I knew someone with a pet retired lab rat, and it lived much longer than the average fancy rat, but even then, it didn't even live half as long as the average cat or dog. If we could breed or treat rodents to live longer, we could keep low-resource pets without as much loss.

There is an excellent "This American Life" episode on rats. The first act is about a guy who keeps rats as pets. It's a sweet story.

https://www.thisamericanlife.org/801/transcript

Re: Scientists reverse brain aging, with a nasal spray

#65

"Reverse brain aging", sure, in the same sense that taking Vitamin C reverses aging. The nasal spray reduced markers of inflammation in hippocampal microglial cells. A lot of things reduce inflammation. That is not "reversing ageing". Of course, "reduces inflammation" doesn't headline very well...

[flagged]

Sure let’s listen to someone with extreme anxiety about the most utterly democratic humane experience

Re: Scientists reverse brain aging, with a nasal spray

#66

"Reverse brain aging", sure, in the same sense that taking Vitamin C reverses aging. The nasal spray reduced markers of inflammation in hippocampal microglial cells. A lot of things reduce inflammation. That is not "reversing ageing". Of course, "reduces inflammation" doesn't headline very well...

This is the current big grift in anti-aging science:

1 - Find a marker correlated with aging across a large sample

2 - Find a medication or supplement that also alters that marker

3 - Do some before and after measurements of the marker with the supplement or medication, and claim that you have reversed aging. Rely on the fact that enough readers won’t look closely enough to wonder if the marker is a true independent variable that represents aging.

Re: Scientists reverse brain aging, with a nasal spray

#67
post #56

Earlier quoted context omitted.

"It's not just x, it's y." Absolutely clear tell, especially at this frequency. Examples from the article below: "Over decades, it doesn’t just wear down, it also starts to run hot." "... the therapy didn’t just clear brain fog, it physically improved the brain’s ability to process and store information." The quotes as well: "'... Not just living longer, but living smarter and healthier,' Shetty said." "'We aren’t ju…

What that is is a tell of bad writing

It's a tell of not writing. It is extremely well-documented as a tell of AI writing.

Re: Scientists reverse brain aging, with a nasal spray

#68
post #18

I take N-acetylcysteine and it helps with brain fog also! Plus it reduces stress and irritability.

And OCD symptoms, and many also benefit from better impulse control. Its more effective than SSRIs for some. NAC is one of the only known treatments for trichotillomania, a under discussed but common condition that causes people to uncontrollably pull their hair out. NAC has also been studied to reduce nicotine and alchohol cravings as well.

Are there any risks associated with NAC supplementation? For example, could long-term usage reduce aptosis and thereby increase risks of developing cancer?

Re: Scientists reverse brain aging, with a nasal spray

#69

Earlier quoted context omitted.

And OCD symptoms, and many also benefit from better impulse control. Its more effective than SSRIs for some. NAC is one of the only known treatments for trichotillomania, a under discussed but common condition that causes people to uncontrollably pull their hair out. NAC has also been studied to reduce nicotine and alchohol cravings as well.

Are there any risks associated with NAC supplementation? For example, could long-term usage reduce aptosis and thereby increase risks of developing cancer?

Some mixed cancer associations in animal models

Re: Scientists reverse brain aging, with a nasal spray

#70
post #34
post #23

Earlier quoted context omitted.

The article is also heavily ai generated, I call bs on every single bit

AI generated? Not demonstrated. Whining by humans claiming AI? Predictable. Probable. Indeed LLM "complete the sentence" predictable.

Sure, a human could be deliberately trying to sound like AI writing, or perhaps they've spent so much time reading it that they think it's normal.
Post reply on HN