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Fecal transplants for autism deliver success in clinical trials (2019)

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Re: Fecal transplants for autism deliver success in clinical trials (2019)

#61
post #4

Earlier quoted context omitted.

You don't eat it, don't be silly.... you stick the poop up your butt

I believe the best procedure is actually sticking it in your nose. (They run a tube through your nose, down your throat, through the stomach to the top of the intestines, and introduce the bacterial slurry there.)

That's a fairly invasive way of doing it. It can be given through pills now. https://www.lhscri.ca/news/innovative-poop-pills-show-promis...

Re: Fecal transplants for autism deliver success in clinical trials (2019)

#62
The number of stories I’ve read in the last 15 years that amount to: “desperate after years of trying everything, we bought a blender and ground up my wife’s shit and put it up my butt, and within a 24 hours I was totally fine”

Is kind of impressive.

Re: Fecal transplants for autism deliver success in clinical trials (2019)

#63
post #36

I got bad chronic constipation after four years as a strict carnivore. I didn't get relief just by adding back fiber, but I did by adding fermented foods like kimchi. I wonder if ferments are a more natural way than fecal transplants to repair the gut microbiome, possibly treating autism. Studies have been non conclusive, but this story makes me think it's worth pursuing.

Why did you follow a strict carnivore diet? Health? Accident? Aside from the constipation did it benefit your health?

Obesity and diabetes. It solved about half of the obesity and all of the diabetes.

Re: Fecal transplants for autism deliver success in clinical trials (2019)

#64

Earlier quoted context omitted.

In some countries the number of kids born through c-section are very high, more than half the kids in Brazil are born that way for example, so definitely people can be healthy without getting it from their mothers.

I read it is a practice these days to do this fecal "rub" for newborns as a way to compensate for the C-section lack of it. I do not know if it happens in Brazil. Another factor to consider.

I've never heard of moms doing fecal rubs, but I've heard of many that do vaginal "transplants". I work in a hospital and we get questions quite a bit, moms will often take moist, sterile gauze and conduct the transplant themselves (staff can't really be involved for liability issues).

Re: Fecal transplants for autism deliver success in clinical trials (2019)

#65
I would still be cautious with such findings. Many autistic people are picky eaters, also some of them have issues with peristalsis. This might affect the microbiome as well. While it's plausible that it might help a subset of people, we should not overgeneralize since autism is a very heterogeneous condition, usually with pronounced genetic predisposition. Overall, it doesn't seem to be a cure.

Re: Fecal transplants for autism deliver success in clinical trials (2019)

#66

The number of stories I’ve read in the last 15 years that amount to: “desperate after years of trying everything, we bought a blender and ground up my wife’s shit and put it up my butt, and within a 24 hours I was totally fine” Is kind of impressive.

my wife is autistic and suffers from many gastro illnesses including MCAS and SIBO. The amount of times i've seriously thought of figuring out the logistics of giving her a fecal transplant from my iron stomach...

Re: Fecal transplants for autism deliver success in clinical trials (2019)

#67

Many autistic children have extremely limited diets. For example, a geneticist friend of mine saw a case where an autistic child had been referred for genetic testing because of horrific, chronic, spontaneous wounds on gums and skin. Turned out to be scurvy, because he had exclusively eaten Wheat Thins for the last 3-4 years, which aren’t fortified with vitamin C. I would fully expect that a monotonous diet leads to…

Imagine the factor overlooked is the nasty but nutritional hospital food they got when receiving the transplant (assuming they got hospitalized).

Re: Fecal transplants for autism deliver success in clinical trials (2019)

#68

I got bad chronic constipation after four years as a strict carnivore. I didn't get relief just by adding back fiber, but I did by adding fermented foods like kimchi. I wonder if ferments are a more natural way than fecal transplants to repair the gut microbiome, possibly treating autism. Studies have been non conclusive, but this story makes me think it's worth pursuing.

>I got bad chronic constipation after four years as a strict carnivore. 2 questions: 1) Did your constipation start right after you did strict carnivore? Or was it after 4 years? 2) List all foods that you ate on strict carnivore. (Include salt, water etc. I presume it won't be a long list)

1) I had constipation on a very high fiber diet before starting carnivore. That was fixed in literally one day. It was the most dramatic change. Then it gradually came back after about 3.5 years.

2) beef, butter, chicken, pork, lamb, eggs, bacon, for > 95%. I do indulge in some processed meats with seasonings. Salt is the only seasoning I add, so I've become a salt snob and get the premium stuff.

After that unspicy diet, full strength kimchi is an experience.

Re: Fecal transplants for autism deliver success in clinical trials (2019)

#69
post #17

Earlier quoted context omitted.

Kids got into tech industry and now it’s their spouses that have to deal with their tism, instead of parents

Self-hatred is not a good look.

Noe you’re making me self-conscious about when I get into a self-hating mood; unfortunately this gives me yet another new reason to hate myself: it’s not a good look.

Re: Fecal transplants for autism deliver success in clinical trials (2019)

#70

Many autistic children have extremely limited diets. For example, a geneticist friend of mine saw a case where an autistic child had been referred for genetic testing because of horrific, chronic, spontaneous wounds on gums and skin. Turned out to be scurvy, because he had exclusively eaten Wheat Thins for the last 3-4 years, which aren’t fortified with vitamin C. I would fully expect that a monotonous diet leads to…

Just to play devil’s advocate, isn’t it also possible that the preference for a monotonous diet is driven by gut makeup?
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