I think if you need something more reliable than us-east-1 that you should be hosting on prem in facilities you own and operate. There aren't that many businesses that truly can't handle the worst case (so far) AWS outage. Payment processing is the strongest example I can come up with that is incompatible with the SLA that a typical cloud provider can offer. Visa going down globally for even a few minutes might be wo…
It’s kind of amazing that after nearly 20 years of “cloud”, the worst case so far still hasn’t been all that bad. Outages are the mildest type of incident. A true cloud disaster would be something like a major S3 data loss event, or a compromise of the IAM control plane. That’s what it would take for people to take multi-region/multi-cloud seriously.