61–70 of 120 posts
Is there any good consensus on what the deal is with this drug yet? I don't know how to think about GLP-1. In the headlines it seems like every month it's a miracle cure for something new, yet we don't really understand it? But it seems like just generally...everyone, including me, would benefit from being on it...? The whole thing makes me uneasy but I'm not exactly sure why outside of it seems weird to have one dru…
Earlier quoted context omitted.
It’s miracle drug, I’ve been on it for a few years now, it would have been sooner but usage data wasn’t available at the scale I needed before the ozempic craze. I have hEDS and part of that is ME/CFS and uncontrollable weight gain, so naturally I was looking for help with weight loss with the understanding that drugs that help with weight loss could be treating an underlying mechanisms that was causing the weight ga…
Does having uncontrollable weight gain help you get jacked? Being jacked and fat is tons of fun, better than being skinny.
Is there any good consensus on what the deal is with this drug yet? I don't know how to think about GLP-1. In the headlines it seems like every month it's a miracle cure for something new, yet we don't really understand it? But it seems like just generally...everyone, including me, would benefit from being on it...? The whole thing makes me uneasy but I'm not exactly sure why outside of it seems weird to have one dru…
I wonder when the first person understood how it worked. (if anyone understands it now?)
Is there any good consensus on what the deal is with this drug yet? I don't know how to think about GLP-1. In the headlines it seems like every month it's a miracle cure for something new, yet we don't really understand it? But it seems like just generally...everyone, including me, would benefit from being on it...? The whole thing makes me uneasy but I'm not exactly sure why outside of it seems weird to have one dru…
The Alzheimer """cure""" claim was already disproven by another study. Aside from that, the people who stop taking GLP, 75% gain 50-75% of their bodyweight back and lose all concomitant cardiovascular, cancer etc. risk benefits. No research out on, say, alcoholism yet, but I'd hazard a guess the results are the same. This is not a cravings loss drug but largely a cravings management drug. Which is still pretty great…
Obesity is associated with increased rate of migraine, so their symptoms could have gone away by virtue of losing weight. Let's see what it does for non obese.
However, not an expert on headaches and can't say if it has anything to do with the migraines in the article. But the point that reducing sugar helps in a myriad of ways, stands and is worth repeating.
Is there any good consensus on what the deal is with this drug yet? I don't know how to think about GLP-1. In the headlines it seems like every month it's a miracle cure for something new, yet we don't really understand it? But it seems like just generally...everyone, including me, would benefit from being on it...? The whole thing makes me uneasy but I'm not exactly sure why outside of it seems weird to have one dru…
There is large-enough consensus on this drug for its main use cases (treating diabetes and obesity), but more importantly for this conversation: it's actually quite common for drugs to get new indications after their initial one --- at which point, there might be a new, broader consensus on what the drug is good for. Clinical trials are designed to treat a very specific subclass of individuals; pharmaceutical compani…
Is there any good consensus on what the deal is with this drug yet? I don't know how to think about GLP-1. In the headlines it seems like every month it's a miracle cure for something new, yet we don't really understand it? But it seems like just generally...everyone, including me, would benefit from being on it...? The whole thing makes me uneasy but I'm not exactly sure why outside of it seems weird to have one dru…
The Alzheimer """cure""" claim was already disproven by another study. Aside from that, the people who stop taking GLP, 75% gain 50-75% of their bodyweight back and lose all concomitant cardiovascular, cancer etc. risk benefits. No research out on, say, alcoholism yet, but I'd hazard a guess the results are the same. This is not a cravings loss drug but largely a cravings management drug. Which is still pretty great…
Is there any good consensus on what the deal is with this drug yet? I don't know how to think about GLP-1. In the headlines it seems like every month it's a miracle cure for something new, yet we don't really understand it? But it seems like just generally...everyone, including me, would benefit from being on it...? The whole thing makes me uneasy but I'm not exactly sure why outside of it seems weird to have one dru…
The Alzheimer """cure""" claim was already disproven by another study. Aside from that, the people who stop taking GLP, 75% gain 50-75% of their bodyweight back and lose all concomitant cardiovascular, cancer etc. risk benefits. No research out on, say, alcoholism yet, but I'd hazard a guess the results are the same. This is not a cravings loss drug but largely a cravings management drug. Which is still pretty great…
Semaglutide goes off-patent in 2032 in the US, and in 2026 in Canada and China:
https://journals.library.columbia.edu/index.php/stlr/blog/vi...
Is there any good consensus on what the deal is with this drug yet? I don't know how to think about GLP-1. In the headlines it seems like every month it's a miracle cure for something new, yet we don't really understand it? But it seems like just generally...everyone, including me, would benefit from being on it...? The whole thing makes me uneasy but I'm not exactly sure why outside of it seems weird to have one dru…
Nobody understands why it all helps, they just noticed it does work for something, quickly pushed it to the market first to get patents and get all the profits from it before generics + derivatives hit their pockets. Now, everyone is studying it because there's all new funding coming in for it and finding other versions of it that they can profit off it. Nobody knows what migraine really is, so this isn't a surprise…
Diet and exercise.
Is there any good consensus on what the deal is with this drug yet? I don't know how to think about GLP-1. In the headlines it seems like every month it's a miracle cure for something new, yet we don't really understand it? But it seems like just generally...everyone, including me, would benefit from being on it...? The whole thing makes me uneasy but I'm not exactly sure why outside of it seems weird to have one dru…
Nobody understands why it all helps, they just noticed it does work for something, quickly pushed it to the market first to get patents and get all the profits from it before generics + derivatives hit their pockets. Now, everyone is studying it because there's all new funding coming in for it and finding other versions of it that they can profit off it. Nobody knows what migraine really is, so this isn't a surprise…
Biology rarely awards something "forever". Maybe one day we can "fix" obese metabolisms permanently by killing off some receptors etc., but in that case, I would be afraid of intractable long-term effects even more.