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Metabolic and cellular differences between sedentary and active individuals

howardluksmd.substack.com

61–70 of 159 posts

Re: Metabolic and cellular differences between sedentary and active individuals

#61

A lot of people in the comments are expressing curiosity about "ideal" amounts of exercise to avoid these sorts of problems. I have a real-life friend whose hobby is studying this stuff. His recommendations boil down to: - 1/week 20 minutes HIIT: 5 minutes warmup, 3x(2 minutes high intensity + 3 minutes low intensity) blocks. - 1/week strength training focused on large muscle groups. - 12,000 steps per day walking (H…

> so its hard to be sure

Who is asking you to be sure in the first place? Why do you need this certainty? Farm animals need the comfort and stability of the farm to survive. They "flourish" within the parameters some one else sets.

In the Elephant-Rider model of how the mind works, people are talking to rider And the elephant.

The elephant just needs some feel good stuff, to momentarily focus shift away from all the unpredictability in the universe, it has no control over - in this case it is being fed - well the story teller who is not sure about anything is atleast "diligent".

When you let go of the story, and realize the elephant is not under your control and can never be, the ride is much smoother. And that's the only story, no SEO game needed to promote the Truth. And truth is - you are just along for the ride. Don't act like a farm animal thinking you are healthy based on how many eggs you have been told to lay. You are a chimp. All animal domestication protocols break down sooner or later when dealing with chimps. Cuz the chimp mind has an elephant in it. Taking it for a wild ride.

Re: Metabolic and cellular differences between sedentary and active individuals

#62

A lot of people in the comments are expressing curiosity about "ideal" amounts of exercise to avoid these sorts of problems. I have a real-life friend whose hobby is studying this stuff. His recommendations boil down to: - 1/week 20 minutes HIIT: 5 minutes warmup, 3x(2 minutes high intensity + 3 minutes low intensity) blocks. - 1/week strength training focused on large muscle groups. - 12,000 steps per day walking (H…

Isn't 12k steps like 6 miles? I could plausibly jog that much, but to walk it every day seems like a huge time commitment.

I get about 6000 daily steps from my commute[0] plus about 2000 from miscellaneous movement around the house and office. The extra 4000 are pretty easy to fill in with a lunchtime walk and some housework.

I don't think most people are going out and just walking for an hour and a half every day. A couple I know like to go for a walk with their morning coffees, for example. They've added walking into something they'd be doing anyway. Other people own a dog, or take their kid to the park each day, or do some other regular activity which integrates walking.

[0] 3000 each way, which is 2km and takes me about 20 minutes at a moderate-to-fast walking pace.

Re: Metabolic and cellular differences between sedentary and active individuals

#63

A lot of people in the comments are expressing curiosity about "ideal" amounts of exercise to avoid these sorts of problems. I have a real-life friend whose hobby is studying this stuff. His recommendations boil down to: - 1/week 20 minutes HIIT: 5 minutes warmup, 3x(2 minutes high intensity + 3 minutes low intensity) blocks. - 1/week strength training focused on large muscle groups. - 12,000 steps per day walking (H…

I love when exercise is hyper-optimized as possible so I can back to what's most important: working at a job I actually hate to make as much money as possible -- the real source of my happiness.

Re: Metabolic and cellular differences between sedentary and active individuals

#64

A lot of people in the comments are expressing curiosity about "ideal" amounts of exercise to avoid these sorts of problems. I have a real-life friend whose hobby is studying this stuff. His recommendations boil down to: - 1/week 20 minutes HIIT: 5 minutes warmup, 3x(2 minutes high intensity + 3 minutes low intensity) blocks. - 1/week strength training focused on large muscle groups. - 12,000 steps per day walking (H…

Isn't 12k steps like 6 miles? I could plausibly jog that much, but to walk it every day seems like a huge time commitment.

12k steps is about 2 hours. It helps a lot to have a walking pad (basically a mini-treadmill), and possibly standing desk.

I do 45 minutes of Anki per day on the walking pad, and then if walking around the city hasn't gotten the other 1.25 hours, I can fill the rest with watching TV on the walking pad.

Re: Metabolic and cellular differences between sedentary and active individuals

#65

A lot of people in the comments are expressing curiosity about "ideal" amounts of exercise to avoid these sorts of problems. I have a real-life friend whose hobby is studying this stuff. His recommendations boil down to: - 1/week 20 minutes HIIT: 5 minutes warmup, 3x(2 minutes high intensity + 3 minutes low intensity) blocks. - 1/week strength training focused on large muscle groups. - 12,000 steps per day walking (H…

Isn't 12k steps like 6 miles? I could plausibly jog that much, but to walk it every day seems like a huge time commitment.

You'll miss walking when your older and your bones turn to dust.

I'd honestly walk as much as you can.

Rust never sleeps.

Re: Metabolic and cellular differences between sedentary and active individuals

#66

A lot of people in the comments are expressing curiosity about "ideal" amounts of exercise to avoid these sorts of problems. I have a real-life friend whose hobby is studying this stuff. His recommendations boil down to: - 1/week 20 minutes HIIT: 5 minutes warmup, 3x(2 minutes high intensity + 3 minutes low intensity) blocks. - 1/week strength training focused on large muscle groups. - 12,000 steps per day walking (H…

People must have very different definitions of HIIT because there's no way someone is sustaining a 2 minute absolute max-effort sprint.

I just aim for zone 5. Usually it takes 45-60 seconds to get into zone 5, then I spend the remaining 60-75 seconds there.

Re: Metabolic and cellular differences between sedentary and active individuals

#67

Earlier quoted context omitted.

Then jog it? That's not a negative.

There's a difference between aerobic and anaerobic exercise. For many people, that manifests as walking being different from running. Which "zone" your heart rate is in (as compared to your maximum heart rate for your age group) tends to be a good indicator of which kind of exercise you're doing. It's important to do both kinds of exercise, with an 80/20 rule being pretty commonly followed.

They wrote "jog" not, "better Kipchoge's marathon record"

Re: Metabolic and cellular differences between sedentary and active individuals

#69
post #3

But how do you know if you exercise enough?

+1. I surf occasionally, and go rock climbing a couple times a week. Compared to the "average American" I suspect I'm pretty active. Compared to other rock climbers and surfers, I'm probably relatively inactive. If I'm not concerned about improving at these hobbies, and just want 80% of the health benefit of being active, am I achieving it? Or am I still below? Edit: From the linked paper: ''' 2.1 Subject Recruitment…

Health is not the same as performance. You can have the former (sounds like you do to me), without the latter (but you're working on it -- what's the rush, going to the Olympics any time soon?).

The extreme of "performance" is rarely healthy.

Re: Metabolic and cellular differences between sedentary and active individuals

#70
post #26

How about boosting mitochondria via supplements? Would that be something to look at? I climbed out of ME/CFS-like neurocovid mainly thanks to boosting mitochondria as much as I could and am wondering if the same lesson could be applied here?

How about just moving around for 30 minutes most days?

Supplements aren't going to help you mentally as a nice walk in the park.

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