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Quantification of fibrinaloid clots in plasma from pediatric Long COVID patients

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Re: Quantification of fibrinaloid clots in plasma from pediatric Long COVID patients

#61

Post by itsme0000 »

Tarsul wrote: post #6

This is (probably) not a Long Covid story but I found that bloodletting (for which I even received money!) gave me back the energy that I was missing for the last few years (e.g. it was impossible to build stamina). I also read about a study about the positive effects of bloodletting[1] that somehow is not all the rage in mainstream news, which I find perplexing. If it might be so easy to improve your health (for som…

Yeah sounds like you get your medical advice from the Kremlin. There no conspiracy to hide the medical benefits of leaching, can you imagine if that actually worked? Every doctor in the world would have to be a complete moron not to notice.

Re: Quantification of fibrinaloid clots in plasma from pediatric Long COVID patients

#62

Post by PaulKeeble »

torben-friis wrote: post #2

Can someone knowledgeable explain the current understanding of Covid’s long time effects? I thought it was still a big unknown and long COVID was still debated as to even having a clear definition.

The WHO [1] has a clinical definition of the disease and some basic data on chance of Covid infections turning into Long Covid. Then the meta study by Eric Topol and Zayad Ali-al from last year is probably a good primer into what is known about the disease that is well established science [2].

Its not a big unknown anymore, its very prevalent, it has a lot of symptoms, it has a clinical definition but its problematic and there are many diagnostic tests that can detect parts of the condition but none has yet reached sufficient prominence to be adopted by healthcare. Healthcare is largely ignoring that Long Covid exists so you can't get diagnosed with it but its very much a real thing and a lot of people have it.

[1]https://www.who.int/news-room/fact-sheets/detail/post-covid-...

[2] https://erictopol.substack.com/p/long-covid-at-3-years

Re: Quantification of fibrinaloid clots in plasma from pediatric Long COVID patients

#63

Post by longcovidthrowa »

tgsovlerkhgsel wrote: post #10

The paper claims that 1/5 of people experience Long COVID after an infection. Given that approximately everyone has caught COVID by now, this does not track with how rarely I've heard of people with it. Wikipedia lists much lower numbers on https://en.wikipedia.org/wiki/Long_COVID (6–7% in adults, ~1% in children, less after vaccination.) and seems to use a more liberal definition than this paper, as it mentions "Mos…

I won't make a claim to the accuracy of the numbers, but I can offer an example of how long COVID can be undercounted. My daughter was a competitive long distance runner. Months after recovering from the acute symptoms of COVID, her performance numbers were still about 10% down and no amount of training would allow her to reach her previous level of performance. After many visits to doctors and specialists, she was eventually diagnosed with long COVID due to lung damage. She's still very fast by most measures, but in track, the difference between being in the 99th percentile and the 89th percentile is the difference between a top 3 finish and a bottom 3 finish. This basically ended her track career. In our case, if we didn't have hard data tracking her before and after performance levels, we may not have ever noticed a difference. How many people who aren't competitive athletes are walking around with 10% degraded pulmonary function and just didn't notice?

Re: Quantification of fibrinaloid clots in plasma from pediatric Long COVID patients

#64

Post by [deleted] »

Tarsul wrote: post #6

This is (probably) not a Long Covid story but I found that bloodletting (for which I even received money!) gave me back the energy that I was missing for the last few years (e.g. it was impossible to build stamina). I also read about a study about the positive effects of bloodletting[1] that somehow is not all the rage in mainstream news, which I find perplexing. If it might be so easy to improve your health (for som…

[deleted]

Re: Quantification of fibrinaloid clots in plasma from pediatric Long COVID patients

#65

Post by bryant »

longcovidthrowa wrote: post #63
tgsovlerkhgsel wrote: post #10

The paper claims that 1/5 of people experience Long COVID after an infection. Given that approximately everyone has caught COVID by now, this does not track with how rarely I've heard of people with it. Wikipedia lists much lower numbers on https://en.wikipedia.org/wiki/Long_COVID (6–7% in adults, ~1% in children, less after vaccination.) and seems to use a more liberal definition than this paper, as it mentions "Mos…

I won't make a claim to the accuracy of the numbers, but I can offer an example of how long COVID can be undercounted. My daughter was a competitive long distance runner. Months after recovering from the acute symptoms of COVID, her performance numbers were still about 10% down and no amount of training would allow her to reach her previous level of performance. After many visits to doctors and specialists, she was e…

It's a pretty sad reflection of the times that there's a need to create a throwaway account to talk about long COVID symptoms, but this is a good personal anecdote to draw attention to what's likely happening. In my case, I only caught covid once - somepoint last year just before I would've gotten the updated booster. It took me well over a year to stop having acute pulmonary issues, and my lung performance is down year over year (measured during high intensity training) even though I finally feel no differently at baseline than I did before I caught it.

Most people don't exploit the full capacity of their bodies and so would never notice, which is essentially the point OP is making. This disease very likely ravaged the 20% claimed, but the vast majority may never know because they're just never pushing their bodies hard enough.

Re: Quantification of fibrinaloid clots in plasma from pediatric Long COVID patients

#66

Post by soks86 »

MontyCarloHall wrote: post #60
cheschire wrote: post #23

Earlier quoted context omitted.

A lot of symptoms of long covid mirror the symptoms of unhealthy living, which may make it so people either dismiss their own symptoms and don't seek diagnosis, or their complaints are dismissed by others for needing to simply improve externalities.

Couldn’t it be the other way round, that changes in health caused by other external factors erroneously get blamed on COVID? For instance, a disproportionate amount of long COVID cases are reported by women between the ages of 40 and 60, the exact age range when most women experience menopause [0]. Menopause can cause brain fog, fatigue, and other symptoms that mirror those of long COVID. Since pretty much everyone h…

Ah yes, you trust

https://www.newsonhealth.co.uk/

over research from Harvard.

One, maybe two non-research docs or... a team of research docs.

Re: Quantification of fibrinaloid clots in plasma from pediatric Long COVID patients

#67

Post by raddan »

itsme0000 wrote: post #57
tgsovlerkhgsel wrote: post #10

The paper claims that 1/5 of people experience Long COVID after an infection. Given that approximately everyone has caught COVID by now, this does not track with how rarely I've heard of people with it. Wikipedia lists much lower numbers on https://en.wikipedia.org/wiki/Long_COVID (6–7% in adults, ~1% in children, less after vaccination.) and seems to use a more liberal definition than this paper, as it mentions "Mos…

Yeah the paper is just lying. “Long Covid” is just a typical response to a severe flu. Many people are just ignorant of the fact that flus can weaken the immune system past the initial infection. It’s well meaning attempt to understand common flu symptoms but they are just relating to COVID to get more clicks and funding.

Did you actually look at any part of the paper? Their approach is not some hand-wavy qualitative measure. They are measuring an actual phenomenon in people with known COVID infections. If you have a methodological problem with the paper, try using facts next time.

Re: Quantification of fibrinaloid clots in plasma from pediatric Long COVID patients

#68

Post by longcovidthrowa »

bryant wrote: post #65
longcovidthrowa wrote: post #63

Earlier quoted context omitted.

I won't make a claim to the accuracy of the numbers, but I can offer an example of how long COVID can be undercounted. My daughter was a competitive long distance runner. Months after recovering from the acute symptoms of COVID, her performance numbers were still about 10% down and no amount of training would allow her to reach her previous level of performance. After many visits to doctors and specialists, she was e…

It's a pretty sad reflection of the times that there's a need to create a throwaway account to talk about long COVID symptoms, but this is a good personal anecdote to draw attention to what's likely happening. In my case, I only caught covid once - somepoint last year just before I would've gotten the updated booster. It took me well over a year to stop having acute pulmonary issues, and my lung performance is down y…

I mainly created the throwaway because I'm sharing personal medical information and I'd rather not do that with my main account where people know me IRL.

Re: Quantification of fibrinaloid clots in plasma from pediatric Long COVID patients

#69

Post by heavyset_go »

tgsovlerkhgsel wrote: post #10

The paper claims that 1/5 of people experience Long COVID after an infection. Given that approximately everyone has caught COVID by now, this does not track with how rarely I've heard of people with it. Wikipedia lists much lower numbers on https://en.wikipedia.org/wiki/Long_COVID (6–7% in adults, ~1% in children, less after vaccination.) and seems to use a more liberal definition than this paper, as it mentions "Mos…

If you get a diagnosis at all, it's going to be a catchall for "idk" like fibromyalgia, CFS, allergies or it's filed away as psychosomatic.

There are probably a lot of syndromes caused by latent infections from virii like EBV, various herpes, HPV, etc that don't go properly diagnosed or treated if they can be treated at all.

Also, it's been found that some viral infections retreat to tissues where their detection might be difficult/impossible without biopsy. You saw this with, for example, Ebola, where survivors could test negative for the virus, but it would still survive and replicate in different isolated tissues like those in the eye.

Re: Quantification of fibrinaloid clots in plasma from pediatric Long COVID patients

#70

Post by bryant »

longcovidthrowa wrote: post #68
bryant wrote: post #65

Earlier quoted context omitted.

It's a pretty sad reflection of the times that there's a need to create a throwaway account to talk about long COVID symptoms, but this is a good personal anecdote to draw attention to what's likely happening. In my case, I only caught covid once - somepoint last year just before I would've gotten the updated booster. It took me well over a year to stop having acute pulmonary issues, and my lung performance is down y…

I mainly created the throwaway because I'm sharing personal medical information and I'd rather not do that with my main account where people know me IRL.

Yeah fair enough. lol
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