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Ozempic linked to lower Alzheimer's risk in people with Type 2 diabetes

nbcnews.com

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Re: Ozempic linked to lower Alzheimer's risk in people with Type 2 diabetes

#61

Post by adventured »

loeg wrote: post #30
thepasswordis wrote: post #18

Of all things my taxes go to, I would love it the United States Government would buy the patent for this drug and make it freely available to anybody who wants it. The number of things it apparently just cures is staggering.

Novo Nordisk's market cap is $500 B, mostly on the basis of GLP-1 drug profits, and the US' entire discretionary budget is $1,700 B. Even if Denmark would allow the sale, and even if somehow the US did not need to pay a premium to shareholders (typical in acquisitions), that would still be a very substantial expenditure.

That's not the way to go about it at all.

The EU loves to ransom US tech companies for budget money. It's very clear that this is an opportunity for the US to similarly damage a big EU company by threatening its patents in the US, or otherwise hitting Novo for tens of billions of dollars in ransom money. The US market is by a huge margin the most important drug market in the world, and especially for Novo.

Find an abusive excuse to invalidate their patents if all else fails. Let Europe learn a valuable lesson in trade wars.

Re: Ozempic linked to lower Alzheimer's risk in people with Type 2 diabetes

#62

Post by ikanreed »

Someone1234 wrote: post #20
AStonesThrow wrote: post #10

Earlier quoted context omitted.

My PCP agrees that the great results I'm getting on Fen-Phen mean I won't need to switch!

GLP-1 have already been on the mass market longer than Fen-Phen (7-years for Fen-Phen Vs. 15+ years, even just Semaglutide has been available longer than Fen-Phen now, and Semaglutide is a third-gen GLP-1). Honestly, this retort can be made about any/all new drugs entering the market. If you had a legitimate retort/critique I'm sure you would have presented it, but this is all we get. This is what happens when you st…

Ultimately the main reason it's bad right now is it's expensive. Far beyond the amount needed to recoup research investment and far far far far far far far far far beyond what it takes to synthesize.

Low-end cost of $1000 a month is a lot. That's an expensive car lease, or half a cheap mortgage.

Re: Ozempic linked to lower Alzheimer's risk in people with Type 2 diabetes

#63

Post by cynicalpeace »

According to this article, it's been (sorta) reproduced once, which is better than most studies. About 40-60% of scientific studies are not reproducible.

Given that, I'd want to see more reproductions.

Also, I'm very annoyed by our American culture which tries to fix problems with drugs, rather than preventing them from happening in the first place with good diet, exercise, sleep and stress management.

Re: Ozempic linked to lower Alzheimer's risk in people with Type 2 diabetes

#64

Post by lazyasciiart »

lawrenceyan wrote: post #57

Why not just lose weight by eating less? I know that sounds like a dumb question. But genuinely, aren’t you just paying money to… not spend the money on food instead?

This is like asking why ADHD patients don’t just get over it by focusing more.

Re: Ozempic linked to lower Alzheimer's risk in people with Type 2 diabetes

#65

Post by [deleted] »

voidfunc wrote: post #19
thepasswordis wrote: post #18

Of all things my taxes go to, I would love it the United States Government would buy the patent for this drug and make it freely available to anybody who wants it. The number of things it apparently just cures is staggering.

Gonna be fun discovering what side effects it causes in 20 years tho.

[deleted]

Re: Ozempic linked to lower Alzheimer's risk in people with Type 2 diabetes

#66

Post by nemomarx »

cynicalpeace wrote: post #63

According to this article, it's been (sorta) reproduced once, which is better than most studies. About 40-60% of scientific studies are not reproducible. Given that, I'd want to see more reproductions. Also, I'm very annoyed by our American culture which tries to fix problems with drugs, rather than preventing them from happening in the first place with good diet, exercise, sleep and stress management.

A drug that reduces appetite is kinda tackling good diet, at least.

Re: Ozempic linked to lower Alzheimer's risk in people with Type 2 diabetes

#67

Post by throwup238 »

tombert wrote: post #59
sandworm101 wrote: post #54

Earlier quoted context omitted.

>> The number of things it apparently just cures is staggering. It cures behavior, not directly disease. I see red flags. Firefly did a movie about a drug that interfered with people's motivations to do things.

Are you seriously suggesting that Ozempic might lead to the Reavers from Firefly?

I don't remember seeing any overweight or obese people on Miranda.

Re: Ozempic linked to lower Alzheimer's risk in people with Type 2 diabetes

#69

Post by zpeti »

cynicalpeace wrote: post #63

According to this article, it's been (sorta) reproduced once, which is better than most studies. About 40-60% of scientific studies are not reproducible. Given that, I'd want to see more reproductions. Also, I'm very annoyed by our American culture which tries to fix problems with drugs, rather than preventing them from happening in the first place with good diet, exercise, sleep and stress management.

I agree with your sentiment, but frankly human nature just doesn’t work that way. We don’t have self control. We weren’t evolved for a world of abundance. This is no one’s fault, and it’s everywhere, china is getting fatter than most countries now.

Realistically, ozempic is a miracle and it seems to be a solution to numerous issues of our world.

It would be nice if it wasn’t so, but apart from the 10% of people who can control themselves (which also causes psychological issues btw), most people just can’t.

Re: Ozempic linked to lower Alzheimer's risk in people with Type 2 diabetes

#70

Post by Tokkemon »

irrational wrote: post #68

How long has Ozempic been around? I've never heard of it until very recently (maybe the last month or two) and suddenly I'm seeing it all the time. Maybe this is an instance of Baader-Meinhof phenomenon, but it doesn't feel like it.

Ozempic has been around about 10 years used mostly for diabetes, but it's use for weight loss management has exploded with the release similar drugs using the same core principles such as Wegovy and Mounjaro. There's also definitely a compounding effect of it being successful for people and them telling their friends.
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