Hacker News Board Hacker News, browsed like a classic message board
Live data from Hacker News

It took my savings and 14 years but I’m about to beat arthritis

thetimes.com

Post reply on HN
Print view View original

61–70 of 185 posts

Re: It took my savings and 14 years but I’m about to beat arthritis

#61

Post by harshreality »

ramraj07 wrote: post #40
Buttons840 wrote: post #33

> The drug is based on a molecule he discovered while working at Pfizer, and can be delivered via a once-a-month EpiPen-style injection, where it restores protective processes to diseased joints and enables the regeneration of affected tissues. It works by blocking a compound that supports the nerve cells involved in transmitting pain signals to the brain. So, it restores lost tissue by numbing nerves? This makes no…

It just takes away the pain, it’s clearly written in the article.

"...it restores protective processes to diseased joints and enables the regeneration of affected tissues..."

"It is hoped the drug — which is not a cure but will make the condition much less painful for sufferers — ..."

Re: It took my savings and 14 years but I’m about to beat arthritis

#62

Post by zeofig »

Buttons840 wrote: post #33

> The drug is based on a molecule he discovered while working at Pfizer, and can be delivered via a once-a-month EpiPen-style injection, where it restores protective processes to diseased joints and enables the regeneration of affected tissues. It works by blocking a compound that supports the nerve cells involved in transmitting pain signals to the brain. So, it restores lost tissue by numbing nerves? This makes no…

The reporting is functioning as intended, don't worry.

Re: It took my savings and 14 years but I’m about to beat arthritis

#64

Post by ekianjo »

zeofig wrote: post #63
purple-leafy wrote: post #21

Paywalled. How legitimate is this? As a young sufferer

It's (presumably) legitimate research, but it's a long way from market. It's basically a hype article.

makes you wonder if it was commissioned...

Re: It took my savings and 14 years but I’m about to beat arthritis

#65

Post by ekianjo »

danpalmer wrote: post #8
thomassmith65 wrote: post #7

The title is misleading. It's not a "cure for Arthritis"; it's a pain killer.

This is true, although it looks like in this case it may be more useful than just another pain killer, in that if you can reduce the joint pain, people might be more active, which may help them lose weight, which may reduce joint pain. If it's safe to take long term (reading between the lines, sounds like it might be compared to other pain killers), then it could have lasting impact on patients beyond them taking it,…

this is for OA, which means people dont have much joint left in the first place. That is what causes pain. not feeling pain will not turn them into marathon runners

Re: It took my savings and 14 years but I’m about to beat arthritis

#66

Post by nwienert »

aszantu wrote: post #47
purple-leafy wrote: post #21

Paywalled. How legitimate is this? As a young sufferer

been on an elimination diet for a while, because if I'm not, I get depression and suicidal ideation. I don't have a diagnosis for arthritis, but I'm testing around a lot and maybe this info helps you in your journey: I make gelatine from pig's feet occasionally, when I make it with just salt and some lemon or vinegar, I don't have problems. Last time I thought, maybe try bell pepper, haven't tried for a while and I s…

I found some relief in the GLP-1 agonists, a surprising amount actually, and that was not due to any weight loss.

Re: It took my savings and 14 years but I’m about to beat arthritis

#67

Post by nwienert »

robbiep wrote: post #55
skybrian wrote: post #36

Earlier quoted context omitted.

I don’t know about this case, but in general, the body’s reaction to pain sometimes makes things worse, so relieving pain can be part of encouraging recovery.

Degenerative diseases don’t de-pathologise when you remove their pain

Pathways that remove pain can be due to healing though, it's a mildly positive indicator.

Re: It took my savings and 14 years but I’m about to beat arthritis

#68

Post by Renaud »

Tangential question: as I now start suffering from arthritis in my hands, I was wondering if there is anything linked to diet that could help reduce it?

I had read that fatty fishes were a good source to reduce pain but in your experience, is there any other food/lifestyle changes that can help alleviate it before resorting to medication?

Re: It took my savings and 14 years but I’m about to beat arthritis

#70

Post by gglanzani »

Renaud wrote: post #68

Tangential question: as I now start suffering from arthritis in my hands, I was wondering if there is anything linked to diet that could help reduce it? I had read that fatty fishes were a good source to reduce pain but in your experience, is there any other food/lifestyle changes that can help alleviate it before resorting to medication?

Avoid carbs
Post reply on HN